Head and neck cancer survivors’ pain in France: the VICAN study

• Published in: Journal of cancer survivorship Vol. 16; no. 1; pp. 119 - 131
• Main Authors: Dugué, Justin, Humbert, Maxime, Bendiane, Marc-Karim, Bouhnik, Anne-Déborah, Babin, Emmanuel, Licaj, Idlir
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2022; Springer Nature B.V; Springer Verlag
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Cancer; Cancer Survivors; Chronic Pain; Chronic Pain - epidemiology; Chronic Pain - etiology; Clinical trials; Complications; Diagnosis; France; France - epidemiology; Head & neck cancer; Head and Neck Neoplasms; Head and Neck Neoplasms - complications; Head and Neck Neoplasms - epidemiology; Health Informatics; Health Promotion and Disease Prevention; Humanities and Social Sciences; Humans; Localization; Medicine; Medicine & Public Health; Middle Aged; Oncology; Oropharynx; Pain; Patients; Physical activity; Primary Care Medicine; Public Health; Quality of Life; Quality of Life Research; Risk factors; Statistics; Surveys and Questionnaires; Survivors; Training; Tumors; Young Adult; France; Head and neck cancer; Pain; VICAN; Chronic pain; Survivors; French cancer survivors
• ISSN: 1932-2259; 1932-2267; 1932-2267
• DOI: 10.1007/s11764-021-01010-0

Purpose Pain is an increasing concern in the growing number of head and neck cancer survivors. This study aimed to analyze the 5-year prevalence of pain in French survivors of head and neck cancer and to identify associated factors. Methods Analyses were performed among 296 5-year cancer survivors diagnosed in 2010. Using multivariable logistic regressions, we studied the associations between pain and factors collected in the French representative national “vie après le cancer” (VICAN) survey. Eligible participants were aged from 18 to 82 years; patients’ living conditions, socioeconomic characteristics, and medical data were collected. Results Pain was reported by 72.6% of the participants. In the multivariable analyses, decreasing level of physical activity was the only determinant of increased overall pain (OR= 2.77, CI= 1.48–5.17). The chronic pain prevalence was 62.3%. The main risk factors found were tumor localization in the oropharynx (OR= 2.49, CI= 1.27–4.88), education (at least a high school’s degree) (OR= 0.33, CI= 0.13–0.9), and decreased physical activity (OR= 2.20, CI= 1.24–3.9). Conclusions Five years after diagnosis, pain is a very frequent sequelae that has a significant impact on quality of life in head and neck cancer survivors. Reduced physical activity, a low level of education, and tumor localization in the oropharynx are factors associated with pain. Implications for Cancer Survivors Pain frequency and its impact on patients’ lives imply that an adaptation must be made in terms of both pain diagnosis and management and the training of healthcare professionals. Clinical trial registration: This is not a clinical trial. ISP number: INSERM C11-63.