IDENTIFYING A SEPSIS SUBPHENOTYPE CHARACTERIZED BY DYSREGULATED LIPOPROTEIN METABOLISM USING A SIMPLIFIED CLINICAL DATA ALGORITHM - Labilloy, Guillaume; Tanaka, Sébastien; Black, Lauren Page; Augustin, Beulah; Hopson, Charlotte; Bethencourt, Joanne; Wu, Dongyuan; Sulaiman, Dawoud; Bertrand, Andrew; Salomão, Reinaldo; Graim, Kiley; Datta, Susmita; et al. (Shock (Augusta, Ga.), 2025)
Keywords: Aged; Algorithms; Cholesterol, HDL - blood; Female; Humans; Lipoproteins - metabolism; Male; Middle Aged; Phenotype; Prospective Studies; Sepsis - blood; Sepsis - metabolism; LDL-C—low-density lipoprotein cholesterol; CI—confidence interval; HDL-C—high-density lipoprotein cholesterol; lipids; NORMO—previously subphenotyped normolipoprotein phenotype; subphenotyping; IQR—interquartile range; LOS—length of stay; SOFA—sequential organ failure assessment; AUC—area under the receiver operating characteristic curve; HYPO—previously subphenotyped hypolipoprotein phenotype; Sepsis; cholesterol; REDCap—Research Electronic Data Capture Database; lipid dysregulation; ICU—intensive care unit; lipoproteins