Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory - Kasza, Ágnes; Penke, Botond; Frank, Zsuzsanna; Bozsó, Zsolt; Szegedi, Viktor; Hunya, Ákos; Németh, Klaudia; Kozma, Gábor; Fülöp, Lívia (Molecules (Basel, Switzerland), 2017)
Keywords: AD rat model; Alzheimer Disease - drug therapy; Alzheimer Disease - physiopathology; amyloid beta; Amyloid beta-Peptides - administration & dosage; Amyloid beta-Peptides - therapeutic use; Animal memory; Animals; Disease Models, Animal; Golgi staining; hippocampus; icv administration; long-term potentiation; Male; Maze Learning - drug effects; Morris water maze; Rats; Rodents; spatial memory; Spatial Memory - drug effects; Morris water maze; AD rat model; hippocampus; Golgi staining; spatial memory; icv administration; amyloid beta; long-term potentiation