Histological assessment of the effects of teriparatide therapy on mandibular fracture healing: A preclinical study
This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model. A unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg...
Saved in:
| Published in | Journal of cranio-maxillo-facial surgery Vol. 48; no. 3; pp. 211 - 216 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Scotland
Elsevier Ltd
01.03.2020
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1010-5182 1878-4119 1878-4119 |
| DOI | 10.1016/j.jcms.2020.01.006 |
Cover
| Abstract | This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.
A unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg teriparatide while the control rats received normal saline, starting from the day of surgery until sacrifice. Twenty rats from each group were sacrificed on postoperative days 10, 20, and 30. The healing process was evaluated histologically and scored using a grading system (ranging from 1 to 10).
On day 10 the fracture gaps of the control and teriparatide groups were mainly filled with fibrous tissue and new trabecular bone, respectively. On day 20 a large amount of new trabecular bone and some areas of fibrocartilaginous tissue were seen in the fracture gaps of the control rats. In the teriparatide group the fracture area was entirely filled with trabecular bone, which in some areas had been replaced by mature bone. On day 30 the fracture gaps of the control group were entirely bridged by new trabecular bone, while in the teriparatide group they was predominantly filled with mature bone. At all three time-points the mean healing scores for the teriparatide group (6.20 ± 0.70, 8.50 ± 0.69, and 9.85 ± 0.37, respectively) were significantly higher (p < 0.001) than for the control group (4.90 ± 0.55, 7.15 ± 0.59, and 8.90 ± 0.64, respectively).
Based on the results of this study, teriparatide should be tested in humans in order to establish whether comparable results can be achieved.
•Subcutaneous injection of 2 μg/kg/day teriparatide enhances and accelerates mandibular fracture healing in rats.•Teriparatide administration results in early and more new trabecular bone formation at the fracture site.•Teriparatide administration promotes remodeling of newly formed trabecular to mature bone at the fracture site. |
|---|---|
| AbstractList | This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.
A unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg teriparatide while the control rats received normal saline, starting from the day of surgery until sacrifice. Twenty rats from each group were sacrificed on postoperative days 10, 20, and 30. The healing process was evaluated histologically and scored using a grading system (ranging from 1 to 10).
On day 10 the fracture gaps of the control and teriparatide groups were mainly filled with fibrous tissue and new trabecular bone, respectively. On day 20 a large amount of new trabecular bone and some areas of fibrocartilaginous tissue were seen in the fracture gaps of the control rats. In the teriparatide group the fracture area was entirely filled with trabecular bone, which in some areas had been replaced by mature bone. On day 30 the fracture gaps of the control group were entirely bridged by new trabecular bone, while in the teriparatide group they was predominantly filled with mature bone. At all three time-points the mean healing scores for the teriparatide group (6.20 ± 0.70, 8.50 ± 0.69, and 9.85 ± 0.37, respectively) were significantly higher (p < 0.001) than for the control group (4.90 ± 0.55, 7.15 ± 0.59, and 8.90 ± 0.64, respectively).
Based on the results of this study, teriparatide should be tested in humans in order to establish whether comparable results can be achieved. This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model. A unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg teriparatide while the control rats received normal saline, starting from the day of surgery until sacrifice. Twenty rats from each group were sacrificed on postoperative days 10, 20, and 30. The healing process was evaluated histologically and scored using a grading system (ranging from 1 to 10). On day 10 the fracture gaps of the control and teriparatide groups were mainly filled with fibrous tissue and new trabecular bone, respectively. On day 20 a large amount of new trabecular bone and some areas of fibrocartilaginous tissue were seen in the fracture gaps of the control rats. In the teriparatide group the fracture area was entirely filled with trabecular bone, which in some areas had been replaced by mature bone. On day 30 the fracture gaps of the control group were entirely bridged by new trabecular bone, while in the teriparatide group they was predominantly filled with mature bone. At all three time-points the mean healing scores for the teriparatide group (6.20 ± 0.70, 8.50 ± 0.69, and 9.85 ± 0.37, respectively) were significantly higher (p < 0.001) than for the control group (4.90 ± 0.55, 7.15 ± 0.59, and 8.90 ± 0.64, respectively). Based on the results of this study, teriparatide should be tested in humans in order to establish whether comparable results can be achieved. •Subcutaneous injection of 2 μg/kg/day teriparatide enhances and accelerates mandibular fracture healing in rats.•Teriparatide administration results in early and more new trabecular bone formation at the fracture site.•Teriparatide administration promotes remodeling of newly formed trabecular to mature bone at the fracture site. This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.OBJECTIVEThis study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.A unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg teriparatide while the control rats received normal saline, starting from the day of surgery until sacrifice. Twenty rats from each group were sacrificed on postoperative days 10, 20, and 30. The healing process was evaluated histologically and scored using a grading system (ranging from 1 to 10).SUBJECTS AND METHODSA unilateral mandibular fracture, 5 mm posterior to the last molar tooth, was surgically created in 120 rats. Half of the animals received a daily subcutaneous injection of 2 μg/kg teriparatide while the control rats received normal saline, starting from the day of surgery until sacrifice. Twenty rats from each group were sacrificed on postoperative days 10, 20, and 30. The healing process was evaluated histologically and scored using a grading system (ranging from 1 to 10).On day 10 the fracture gaps of the control and teriparatide groups were mainly filled with fibrous tissue and new trabecular bone, respectively. On day 20 a large amount of new trabecular bone and some areas of fibrocartilaginous tissue were seen in the fracture gaps of the control rats. In the teriparatide group the fracture area was entirely filled with trabecular bone, which in some areas had been replaced by mature bone. On day 30 the fracture gaps of the control group were entirely bridged by new trabecular bone, while in the teriparatide group they was predominantly filled with mature bone. At all three time-points the mean healing scores for the teriparatide group (6.20 ± 0.70, 8.50 ± 0.69, and 9.85 ± 0.37, respectively) were significantly higher (p < 0.001) than for the control group (4.90 ± 0.55, 7.15 ± 0.59, and 8.90 ± 0.64, respectively).RESULTSOn day 10 the fracture gaps of the control and teriparatide groups were mainly filled with fibrous tissue and new trabecular bone, respectively. On day 20 a large amount of new trabecular bone and some areas of fibrocartilaginous tissue were seen in the fracture gaps of the control rats. In the teriparatide group the fracture area was entirely filled with trabecular bone, which in some areas had been replaced by mature bone. On day 30 the fracture gaps of the control group were entirely bridged by new trabecular bone, while in the teriparatide group they was predominantly filled with mature bone. At all three time-points the mean healing scores for the teriparatide group (6.20 ± 0.70, 8.50 ± 0.69, and 9.85 ± 0.37, respectively) were significantly higher (p < 0.001) than for the control group (4.90 ± 0.55, 7.15 ± 0.59, and 8.90 ± 0.64, respectively).Based on the results of this study, teriparatide should be tested in humans in order to establish whether comparable results can be achieved.CONCLUSIONBased on the results of this study, teriparatide should be tested in humans in order to establish whether comparable results can be achieved. |
| Author | Bigonah, Nemat Dehghan, Arash Doulati, Shideh Mohammad Gholi Mezerji, Naser Zandi, Mohammad |
| Author_xml | – sequence: 1 givenname: Mohammad surname: Zandi fullname: Zandi, Mohammad organization: Department of Oral and Maxillofacial Surgery, Hamadan University of Medical Sciences, Hamadan, Iran – sequence: 2 givenname: Arash surname: Dehghan fullname: Dehghan, Arash organization: Department of Pathology, Hamadan University of Medical Sciences, Hamadan, Iran – sequence: 3 givenname: Nemat surname: Bigonah fullname: Bigonah, Nemat email: dr.bigonah59@yahoo.com organization: Department of Oral and Maxillofacial Surgery, Hamadan University of Medical Sciences, Hamadan, Iran – sequence: 4 givenname: Shideh surname: Doulati fullname: Doulati, Shideh organization: Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran – sequence: 5 givenname: Naser surname: Mohammad Gholi Mezerji fullname: Mohammad Gholi Mezerji, Naser organization: Department of Biostatistics and Epidemiology, Hamadan University of Medical Sciences, Hamadan, Iran |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32014386$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkcFu3CAURVGUqEmm_YEsKpbd2H2Ax4OjbqKobSpF6iZdI8DPCVMbXMCV5u_LZDKbLNIVD3HPkzj3kpz64JGQKwY1A9Z-3tZbO6WaA4caWA3QnpALJjeyahjrTssMDKo1k_ycXKa0hZIA2b0j54IDa4RsL0i8cymHMTw6q0eqU8KUJvSZhoHmJ6Q4DGhzer5idLOOOrse929RzzsaPJ20751ZRh3pELXNS0T6hHp0_vGa3tA5oi3z8_6Ul373npwNekz44eVckV_fvj7c3lX3P7__uL25r2wDm1xpY_RaCM5ML5jtmrWQTAoLG9t1pnxAd-2wYdY0shNmwAY70zSCm2bomQDBxYp8OuydY_izYMpqcsniOGqPYUmKizV0DNpiYkU-vkQXM2Gv5ugmHXfq6KkE5CFgY0gp4qCsy8VE8DlqNyoGal-J2qp9JWpfiQKmivCC8lfocfub0JcDhEXQX4dRJevQW-xd0ZlVH9zb-PUr_FjBb9z9D_4H1xa5bg |
| CitedBy_id | crossref_primary_10_5371_hp_2020_32_4_182 crossref_primary_10_1016_j_bioadv_2022_213249 crossref_primary_10_1007_s12011_024_04462_4 crossref_primary_10_1016_j_jcms_2021_02_017 |
| Cites_doi | 10.1016/j.jcot.2016.01.003 10.1016/j.joms.2009.09.045 10.1016/j.jcms.2018.11.023 10.1016/S0266-4356(03)00075-5 10.1016/j.bone.2005.02.002 10.1016/j.joms.2010.10.013 10.1371/journal.pone.0031771 10.1016/j.ijom.2015.11.022 10.1016/j.jcms.2018.12.010 10.1007/s00223-011-9503-3 10.1016/j.ijscr.2016.02.028 10.1016/j.bjoms.2004.02.020 10.1007/s00198-009-1061-4 10.1055/s-0030-1262443 10.1016/j.injury.2017.05.016 10.1016/j.jcms.2019.04.011 10.1097/01.blo.0000087322.60612.14 10.1016/j.injury.2017.10.026 10.1016/j.jcms.2018.11.015 10.1359/jbmr.1999.14.6.960 10.1016/S0020-1383(13)70013-5 10.1016/j.injury.2008.06.025 10.1016/j.joms.2005.10.027 10.1359/jbmr.2002.17.11.2038 10.1016/S1079-2104(96)80431-8 10.1016/j.jcms.2019.01.023 10.1016/j.jocn.2011.04.048 10.1016/j.jot.2015.08.001 10.1016/j.jcms.2018.05.012 10.1016/j.ydbio.2014.08.007 10.1016/j.jcms.2017.05.011 10.1016/S0020-1383(16)30009-2 10.1016/j.jcms.2017.12.027 10.1016/j.jphotobiol.2016.03.041 10.1359/jbmr.060802 |
| ContentType | Journal Article |
| Copyright | 2020 European Association for Cranio-Maxillo-Facial Surgery Copyright © 2020 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. |
| Copyright_xml | – notice: 2020 European Association for Cranio-Maxillo-Facial Surgery – notice: Copyright © 2020 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. |
| DBID | AAYXX CITATION NPM 7X8 |
| DOI | 10.1016/j.jcms.2020.01.006 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Dentistry |
| EISSN | 1878-4119 |
| EndPage | 216 |
| ExternalDocumentID | 32014386 10_1016_j_jcms_2020_01_006 S1010518220300147 |
| Genre | Journal Article |
| GroupedDBID | --- --K --M .1- .55 .FO .GJ .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 3O- 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM AAEDT AAEDW AAGKA AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAXKI AAXUO AAYWO ABBQC ABFNM ABJNI ABMAC ABMZM ABWVN ABXDB ACDAQ ACGFS ACIEU ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADMUD ADNMO AEBSH AEIPS AEKER AENEX AEUPX AEVXI AFFNX AFJKZ AFPUW AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CAG COF CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HDX HEK HMK HMO HVGLF HZ~ IHE J1W KOM M27 M41 MO0 N9A O-L O9- OAUVE OF. OQ0 OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SAE SDF SDG SEL SES SEW SPCBC SSH SSZ T5K UHS WUQ X7M Z5R ZGI ~G- AACTN AAIAV ABLVK ABYKQ AFCTW AFKWA AHPSJ AJBFU AJOXV AMFUW EFLBG LCYCR RIG AAYXX ACLOT CITATION ~HD NPM 7X8 |
| ID | FETCH-LOGICAL-c407t-abba53321bd31c94538183c07c99b320a96f71cb4893bfe4e9b4432b4fd130323 |
| IEDL.DBID | .~1 |
| ISSN | 1010-5182 1878-4119 |
| IngestDate | Fri Sep 05 02:40:48 EDT 2025 Wed Feb 19 02:30:59 EST 2025 Wed Oct 01 01:59:59 EDT 2025 Thu Apr 24 23:08:06 EDT 2025 Fri Feb 23 02:49:12 EST 2024 Tue Aug 26 16:34:28 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | Healing Mandible Fracture Teriparatide Animal study |
| Language | English |
| License | Copyright © 2020 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c407t-abba53321bd31c94538183c07c99b320a96f71cb4893bfe4e9b4432b4fd130323 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 32014386 |
| PQID | 2350910614 |
| PQPubID | 23479 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_2350910614 pubmed_primary_32014386 crossref_citationtrail_10_1016_j_jcms_2020_01_006 crossref_primary_10_1016_j_jcms_2020_01_006 elsevier_sciencedirect_doi_10_1016_j_jcms_2020_01_006 elsevier_clinicalkey_doi_10_1016_j_jcms_2020_01_006 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | March 2020 2020-03-00 2020-Mar 20200301 |
| PublicationDateYYYYMMDD | 2020-03-01 |
| PublicationDate_xml | – month: 03 year: 2020 text: March 2020 |
| PublicationDecade | 2020 |
| PublicationPlace | Scotland |
| PublicationPlace_xml | – name: Scotland |
| PublicationTitle | Journal of cranio-maxillo-facial surgery |
| PublicationTitleAlternate | J Craniomaxillofac Surg |
| PublicationYear | 2020 |
| Publisher | Elsevier Ltd |
| Publisher_xml | – name: Elsevier Ltd |
| References | Griffin, Smith, Costa (bib17) 2009; 40 Collinge, Favela (bib12) 2016; 47 Li, Liu, Ni, Liu, Sun, Lin (bib23) 2019; 47 Zandi, Dehghan, Zandipoor, Amini, Doulati (bib38) 2018; 46 Pietrogrande, Raimondo (bib28) 2013; 44 Rasubala, Yoshikawa, Islam, Nagata, Iijima, Ohishi (bib29) 2004; 42 Aydoğan, Özel, İltar, Kara, Özmeriç, Alemdaroğlu (bib5) 2016; 7 Karayürek, Kadiroğlu, Nergiz, Coşkun Akçay, Tunik (bib19) 2019; 47 Abdelrahim, Hassanein, Dahaba (bib1) 2011; 69 Bonavolontà, Dell'aversana Orabona, Abbate, Vaira, Lo Faro, Petrocelli (bib6) 2017; 45 Rowshan, Parham, Baur, McEntee, Cauley, Carriere (bib31) 2010; 68 Cecchi, Bennet, Arora (bib8) 2015; 4 Afat, Akdoğan, Gönül (bib2) 2019; 47 Chintamaneni, Finzel, Gruber (bib10) 2010; 21 Coppola, Del Buono, Maffulli (bib14) 2014; 12 Komatsubara, Mori, Mashiba, Nonaka, Seki, Akiyama (bib21) 2005; 36 Medalha, Santos, Veronez Sde, Fernandes, Magri, Renno (bib24) 2016; 159 Alkhiary, Gerstenfeld, Krall, Westmore, Sato, Mitlak (bib3) 2005; 87 Yao, Shimo, Ono, Obata, Yoshioka, Sasaki (bib34) 2016; 21 Rasubala, Yoshikawa, Nagata, Iijima, Ohishi (bib30) 2003; 41 Çırak, Özyurt, Peker, Ömeroğlu, Güngör (bib11) 2018; 46 Eli Lilly and Co (bib15) 2002 Erdogan, Esen, Ustün, Kürkçü, Akova, Gönlüşen (bib16) 2006; 64 Hollinger, Wong Mark (bib18) 1996; 82 Zandi, Dehghan, Amini, Rezaeian, Doulati (bib36) 2017; 48 Mognetti, Marino, Barberis, Martin, Bala, Di Carlo (bib25) 2011; 89 Yu, Lieu, Hu, Miclau, Colnot (bib35) 2012; 7 Conforte, Alves, Sánchez Mdel, Ponzoni (bib13) 2016; 45 Perry, Prpa, Rouse, Piper, Hanssen, Steckelberg (bib27) 2003; 414 Leighton, Watson, Giannoudis, Papakostidis, Harrison, Steen (bib22) 2017; 48 Andreassen, Ejersted, Oxlund (bib4) 1999; 14 Brunnemann, Reisinger, Ganzer, Schober (bib7) 2010; 135 Tu, Liu, Lee, Chen (bib33) 2012; 19 Nakajima, Shimoji, Shiomi, Shimizu, Moriya, Einhorn (bib26) 2002; 17 Zandi, Dehghan, Gheysari, Rezaeian, Mohammad Gholi Mezerji (bib37) 2019; 47 Kenan, Onur, Solakoğlu, Kotil, Ramazanoğlu, Çelik (bib20) 2019; 47 Chen, Miller, Delmas, Misurski, Krege (bib9) 2006; 21 Takeyama, Chatani, Takano, Kudo (bib32) 2014; 394 Zandi (10.1016/j.jcms.2020.01.006_bib37) 2019; 47 Perry (10.1016/j.jcms.2020.01.006_bib27) 2003; 414 Zandi (10.1016/j.jcms.2020.01.006_bib36) 2017; 48 Leighton (10.1016/j.jcms.2020.01.006_bib22) 2017; 48 Griffin (10.1016/j.jcms.2020.01.006_bib17) 2009; 40 Cecchi (10.1016/j.jcms.2020.01.006_bib8) 2015; 4 Erdogan (10.1016/j.jcms.2020.01.006_bib16) 2006; 64 Tu (10.1016/j.jcms.2020.01.006_bib33) 2012; 19 Afat (10.1016/j.jcms.2020.01.006_bib2) 2019; 47 Eli Lilly and Co (10.1016/j.jcms.2020.01.006_bib15) 2002 Mognetti (10.1016/j.jcms.2020.01.006_bib25) 2011; 89 Aydoğan (10.1016/j.jcms.2020.01.006_bib5) 2016; 7 Yao (10.1016/j.jcms.2020.01.006_bib34) 2016; 21 Hollinger (10.1016/j.jcms.2020.01.006_bib18) 1996; 82 Abdelrahim (10.1016/j.jcms.2020.01.006_bib1) 2011; 69 Kenan (10.1016/j.jcms.2020.01.006_bib20) 2019; 47 Li (10.1016/j.jcms.2020.01.006_bib23) 2019; 47 Rasubala (10.1016/j.jcms.2020.01.006_bib29) 2004; 42 Zandi (10.1016/j.jcms.2020.01.006_bib38) 2018; 46 Takeyama (10.1016/j.jcms.2020.01.006_bib32) 2014; 394 Yu (10.1016/j.jcms.2020.01.006_bib35) 2012; 7 Coppola (10.1016/j.jcms.2020.01.006_bib14) 2014; 12 Karayürek (10.1016/j.jcms.2020.01.006_bib19) 2019; 47 Pietrogrande (10.1016/j.jcms.2020.01.006_bib28) 2013; 44 Rowshan (10.1016/j.jcms.2020.01.006_bib31) 2010; 68 Chintamaneni (10.1016/j.jcms.2020.01.006_bib10) 2010; 21 Komatsubara (10.1016/j.jcms.2020.01.006_bib21) 2005; 36 Brunnemann (10.1016/j.jcms.2020.01.006_bib7) 2010; 135 Medalha (10.1016/j.jcms.2020.01.006_bib24) 2016; 159 Çırak (10.1016/j.jcms.2020.01.006_bib11) 2018; 46 Andreassen (10.1016/j.jcms.2020.01.006_bib4) 1999; 14 Bonavolontà (10.1016/j.jcms.2020.01.006_bib6) 2017; 45 Nakajima (10.1016/j.jcms.2020.01.006_bib26) 2002; 17 Rasubala (10.1016/j.jcms.2020.01.006_bib30) 2003; 41 Chen (10.1016/j.jcms.2020.01.006_bib9) 2006; 21 Alkhiary (10.1016/j.jcms.2020.01.006_bib3) 2005; 87 Collinge (10.1016/j.jcms.2020.01.006_bib12) 2016; 47 Conforte (10.1016/j.jcms.2020.01.006_bib13) 2016; 45 |
| References_xml | – volume: 19 start-page: 532 year: 2012 end-page: 535 ident: bib33 article-title: Treatment of repeated and multiple new-onset osteoporotic vertebral compression fractures with teriparatide publication-title: J Clin Neurosci – volume: 17 start-page: 2038 year: 2002 end-page: 2047 ident: bib26 article-title: Mechanisms for the enhancement of fracture healing in rats treated with intermittent low-dose human parathyroid hormone (1-34) publication-title: J Bone Miner Res – volume: 7 start-page: 90 year: 2016 end-page: 94 ident: bib5 article-title: The effect of vitamin D and bisphosphonate on fracture healing: an experimental study publication-title: J Clin Orthop Trauma – volume: 394 start-page: 292 year: 2014 end-page: 304 ident: bib32 article-title: In-vivo imaging of the fracture healing in medaka revealed two types of osteoclasts before and after the callus formation by osteoblasts publication-title: Dev Biol – volume: 21 start-page: 1059 year: 2010 end-page: 1063 ident: bib10 article-title: Successful treatment of sternal fracture nonunion with teriparatide publication-title: Osteoporos Int – volume: 4 start-page: 28 year: 2015 end-page: 34 ident: bib8 article-title: Bone morphogenetic protein-7: review of signalling and efficacy in fracture healing publication-title: J Orthop Translat – volume: 68 start-page: 260 year: 2010 end-page: 267 ident: bib31 article-title: Effect of intermittent systemic administration of recombinant parathyroid hormone (1-34) on mandibular fracture healing in rats publication-title: J Oral Maxillofac Surg – volume: 47 start-page: 120 year: 2019 end-page: 126 ident: bib37 article-title: Evaluation of teriparatide effect on healing of autografted mandibular defects in rats publication-title: J Craniomaxillofac Surg – volume: 21 start-page: 1785 year: 2006 end-page: 1790 ident: bib9 article-title: Change in lumbar spine BMD and vertebral fracture risk reduction in teriparatide-treated postmenopausal women with osteoporosis publication-title: J Bone Miner Res – volume: 46 start-page: 466 year: 2018 end-page: 472 ident: bib38 article-title: Effect of different doses and durations of teriparatide therapy on resolution of medication-related osteonecrosis of the jaw: a randomized, controlled preclinical study in rats publication-title: J Craniomaxillofac Surg – volume: 36 start-page: 678 year: 2005 end-page: 687 ident: bib21 article-title: Human parathyroid hormone (1-34) accelerates the fracture healing process of woven to lamellar bone replacement and new cortical shell formation in rat femora publication-title: Bone – volume: 46 start-page: 1147 year: 2018 end-page: 1152 ident: bib11 article-title: Comparative evaluation of various low-level laser therapies on bone healing following tooth extraction: an experimental animal study publication-title: J Craniomaxillofac Surg – volume: 414 start-page: 95 year: 2003 end-page: 100 ident: bib27 article-title: Levofloxacin and trovafloxacin inhibition of experimental fracture-healing publication-title: Clin Orthop Relat Res – volume: 40 start-page: 158 year: 2009 end-page: 162 ident: bib17 article-title: The clinical use of platelet-rich plasma in the promotion of bone healing: a systematic review publication-title: Injury – volume: 21 start-page: 151 year: 2016 end-page: 153 ident: bib34 article-title: Successful treatment of osteonecrosis-induced fractured mandible with teriparatide therapy: a case report publication-title: Int J Surg Case Rep – volume: 7 start-page: 31771 year: 2012 ident: bib35 article-title: Site specific effects of zoledronic acid during tibial and mandibular fracture repair publication-title: PLoS One – volume: 135 start-page: 1538 year: 2010 end-page: 1541 ident: bib7 article-title: Parathyroid hormone injection to counteract delayed bone fractures publication-title: Dtsch Med Wochenschr – volume: 41 start-page: 173 year: 2003 end-page: 178 ident: bib30 article-title: Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats publication-title: Br J Oral Maxillofac Surg – volume: 87 start-page: 731 year: 2005 end-page: 741 ident: bib3 article-title: Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34) publication-title: J Bone Jt Surg Am – volume: 14 start-page: 960 year: 1999 end-page: 968 ident: bib4 article-title: Intermittent parathyroid hormone (1-34) treatment increases callus formation and mechanical strength of healing rat fractures publication-title: J Bone Miner Res – volume: 44 start-page: S54 year: 2013 end-page: S57 ident: bib28 article-title: Teriparatide in the treatment of non-unions: scientific and clinical evidences publication-title: Injury – year: 2002 ident: bib15 article-title: United States package insert: forteo [teriparatide (rDNA origin) injection]. Indianapolis, IN – volume: 89 start-page: 163 year: 2011 end-page: 171 ident: bib25 article-title: Experimental stimulation of bone healing with teriparatide: histomorphometric and microhardness analysis in a mouse model of closed fracture publication-title: Calcif Tissue Int – volume: 42 start-page: 315 year: 2004 end-page: 322 ident: bib29 article-title: Comparison of the healing process in plated and non-plated fractures of the mandible in rats publication-title: Br J Oral Maxillofac Surg – volume: 159 start-page: 179 year: 2016 end-page: 185 ident: bib24 article-title: Low level laser therapy accelerates bone healing in spinal cord injured rats publication-title: J Photochem Photobiol – volume: 48 start-page: 2683 year: 2017 end-page: 2687 ident: bib36 article-title: Evaluation of mandibular fracture healing in rats under zoledronate therapy: a histologic study publication-title: Injury – volume: 64 start-page: 180 year: 2006 end-page: 188 ident: bib16 article-title: Effects of low-intensity pulsed ultrasound on healing of mandibular fractures: an experimental study in rabbits publication-title: J Oral Maxillofac Surg – volume: 45 start-page: 1319 year: 2017 end-page: 1326 ident: bib6 article-title: The epidemiological analysis of maxillofacial fractures in Italy: the experience of a single tertiary center with 1720 patients publication-title: J Craniomaxillofac Surg – volume: 48 start-page: 133947 year: 2017 ident: bib22 article-title: Healing of fracture nonunions treated with low-intensity pulsed ultrasound (LIPUS): a systematic review and meta-analysis publication-title: Injury – volume: 82 start-page: 594 year: 1996 end-page: 606 ident: bib18 article-title: The integrated processes of hard tissue regeneration with special emphasis on fracture healing publication-title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod – volume: 47 start-page: 473 year: 2019 end-page: 483 ident: bib20 article-title: Investigation of the effects of semaphorin 3A on new bone formation in a rat calvarial defect model publication-title: J Craniomaxillofac Surg – volume: 69 start-page: 1708 year: 2011 end-page: 1717 ident: bib1 article-title: Effect of pulsed electromagnetic field on healing of mandibular fracture: a preliminary clinical study publication-title: J Oral Maxillofac Surg – volume: 47 start-page: 815 year: 2019 end-page: 825 ident: bib19 article-title: Combining platelet rich fibrin with different bone graft materials: an experimental study on the histopathological and immunohistochemical aspects of bone healing publication-title: J Craniomaxillofac Surg – volume: 47 start-page: S36 year: 2016 end-page: S38 ident: bib12 article-title: Use of teriparatide in osteoporotic fracture patients publication-title: Injury – volume: 45 start-page: 575 year: 2016 end-page: 581 ident: bib13 article-title: Clinical paper trauma impact of trauma and surgical treatment on the quality of life of patients with facial fractures publication-title: Int J Oral Maxillofac Surg – volume: 47 start-page: 1147 year: 2019 end-page: 1154 ident: bib23 article-title: Enhanced osteogenic healing process of rat tooth sockets using a novel simvastatin-loaded injectable microsphere-hydrogel system publication-title: J Craniomaxillofac Surg – volume: 47 start-page: 280 year: 2019 end-page: 286 ident: bib2 article-title: Effects of leukocyte- and platelet-rich fibrin alone and combined with hyaluronic acid on early soft tissue healing after surgical extraction of impacted mandibular third molars: a prospective clinical study publication-title: J Craniomaxillofac Surg – volume: 12 start-page: 47 year: 2014 end-page: 53 ident: bib14 article-title: Teriparatide in fracture non-unions publication-title: Transl Med UniSa – volume: 7 start-page: 90 year: 2016 ident: 10.1016/j.jcms.2020.01.006_bib5 article-title: The effect of vitamin D and bisphosphonate on fracture healing: an experimental study publication-title: J Clin Orthop Trauma doi: 10.1016/j.jcot.2016.01.003 – volume: 68 start-page: 260 year: 2010 ident: 10.1016/j.jcms.2020.01.006_bib31 article-title: Effect of intermittent systemic administration of recombinant parathyroid hormone (1-34) on mandibular fracture healing in rats publication-title: J Oral Maxillofac Surg doi: 10.1016/j.joms.2009.09.045 – volume: 47 start-page: 280 year: 2019 ident: 10.1016/j.jcms.2020.01.006_bib2 article-title: Effects of leukocyte- and platelet-rich fibrin alone and combined with hyaluronic acid on early soft tissue healing after surgical extraction of impacted mandibular third molars: a prospective clinical study publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2018.11.023 – volume: 41 start-page: 173 year: 2003 ident: 10.1016/j.jcms.2020.01.006_bib30 article-title: Platelet-derived growth factor and bone morphogenetic protein in the healing of mandibular fractures in rats publication-title: Br J Oral Maxillofac Surg doi: 10.1016/S0266-4356(03)00075-5 – volume: 36 start-page: 678 year: 2005 ident: 10.1016/j.jcms.2020.01.006_bib21 article-title: Human parathyroid hormone (1-34) accelerates the fracture healing process of woven to lamellar bone replacement and new cortical shell formation in rat femora publication-title: Bone doi: 10.1016/j.bone.2005.02.002 – volume: 69 start-page: 1708 year: 2011 ident: 10.1016/j.jcms.2020.01.006_bib1 article-title: Effect of pulsed electromagnetic field on healing of mandibular fracture: a preliminary clinical study publication-title: J Oral Maxillofac Surg doi: 10.1016/j.joms.2010.10.013 – volume: 87 start-page: 731 year: 2005 ident: 10.1016/j.jcms.2020.01.006_bib3 article-title: Enhancement of experimental fracture-healing by systemic administration of recombinant human parathyroid hormone (PTH 1-34) publication-title: J Bone Jt Surg Am – volume: 7 start-page: 31771 year: 2012 ident: 10.1016/j.jcms.2020.01.006_bib35 article-title: Site specific effects of zoledronic acid during tibial and mandibular fracture repair publication-title: PLoS One doi: 10.1371/journal.pone.0031771 – volume: 45 start-page: 575 year: 2016 ident: 10.1016/j.jcms.2020.01.006_bib13 article-title: Clinical paper trauma impact of trauma and surgical treatment on the quality of life of patients with facial fractures publication-title: Int J Oral Maxillofac Surg doi: 10.1016/j.ijom.2015.11.022 – volume: 47 start-page: 473 year: 2019 ident: 10.1016/j.jcms.2020.01.006_bib20 article-title: Investigation of the effects of semaphorin 3A on new bone formation in a rat calvarial defect model publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2018.12.010 – volume: 89 start-page: 163 year: 2011 ident: 10.1016/j.jcms.2020.01.006_bib25 article-title: Experimental stimulation of bone healing with teriparatide: histomorphometric and microhardness analysis in a mouse model of closed fracture publication-title: Calcif Tissue Int doi: 10.1007/s00223-011-9503-3 – volume: 21 start-page: 151 year: 2016 ident: 10.1016/j.jcms.2020.01.006_bib34 article-title: Successful treatment of osteonecrosis-induced fractured mandible with teriparatide therapy: a case report publication-title: Int J Surg Case Rep doi: 10.1016/j.ijscr.2016.02.028 – volume: 42 start-page: 315 year: 2004 ident: 10.1016/j.jcms.2020.01.006_bib29 article-title: Comparison of the healing process in plated and non-plated fractures of the mandible in rats publication-title: Br J Oral Maxillofac Surg doi: 10.1016/j.bjoms.2004.02.020 – volume: 21 start-page: 1059 year: 2010 ident: 10.1016/j.jcms.2020.01.006_bib10 article-title: Successful treatment of sternal fracture nonunion with teriparatide publication-title: Osteoporos Int doi: 10.1007/s00198-009-1061-4 – volume: 135 start-page: 1538 year: 2010 ident: 10.1016/j.jcms.2020.01.006_bib7 article-title: Parathyroid hormone injection to counteract delayed bone fractures publication-title: Dtsch Med Wochenschr doi: 10.1055/s-0030-1262443 – year: 2002 ident: 10.1016/j.jcms.2020.01.006_bib15 – volume: 48 start-page: 133947 year: 2017 ident: 10.1016/j.jcms.2020.01.006_bib22 article-title: Healing of fracture nonunions treated with low-intensity pulsed ultrasound (LIPUS): a systematic review and meta-analysis publication-title: Injury doi: 10.1016/j.injury.2017.05.016 – volume: 47 start-page: 1147 year: 2019 ident: 10.1016/j.jcms.2020.01.006_bib23 article-title: Enhanced osteogenic healing process of rat tooth sockets using a novel simvastatin-loaded injectable microsphere-hydrogel system publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2019.04.011 – volume: 414 start-page: 95 year: 2003 ident: 10.1016/j.jcms.2020.01.006_bib27 article-title: Levofloxacin and trovafloxacin inhibition of experimental fracture-healing publication-title: Clin Orthop Relat Res doi: 10.1097/01.blo.0000087322.60612.14 – volume: 48 start-page: 2683 year: 2017 ident: 10.1016/j.jcms.2020.01.006_bib36 article-title: Evaluation of mandibular fracture healing in rats under zoledronate therapy: a histologic study publication-title: Injury doi: 10.1016/j.injury.2017.10.026 – volume: 47 start-page: 120 year: 2019 ident: 10.1016/j.jcms.2020.01.006_bib37 article-title: Evaluation of teriparatide effect on healing of autografted mandibular defects in rats publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2018.11.015 – volume: 14 start-page: 960 year: 1999 ident: 10.1016/j.jcms.2020.01.006_bib4 article-title: Intermittent parathyroid hormone (1-34) treatment increases callus formation and mechanical strength of healing rat fractures publication-title: J Bone Miner Res doi: 10.1359/jbmr.1999.14.6.960 – volume: 44 start-page: S54 issue: Suppl 1 year: 2013 ident: 10.1016/j.jcms.2020.01.006_bib28 article-title: Teriparatide in the treatment of non-unions: scientific and clinical evidences publication-title: Injury doi: 10.1016/S0020-1383(13)70013-5 – volume: 40 start-page: 158 year: 2009 ident: 10.1016/j.jcms.2020.01.006_bib17 article-title: The clinical use of platelet-rich plasma in the promotion of bone healing: a systematic review publication-title: Injury doi: 10.1016/j.injury.2008.06.025 – volume: 64 start-page: 180 year: 2006 ident: 10.1016/j.jcms.2020.01.006_bib16 article-title: Effects of low-intensity pulsed ultrasound on healing of mandibular fractures: an experimental study in rabbits publication-title: J Oral Maxillofac Surg doi: 10.1016/j.joms.2005.10.027 – volume: 17 start-page: 2038 year: 2002 ident: 10.1016/j.jcms.2020.01.006_bib26 article-title: Mechanisms for the enhancement of fracture healing in rats treated with intermittent low-dose human parathyroid hormone (1-34) publication-title: J Bone Miner Res doi: 10.1359/jbmr.2002.17.11.2038 – volume: 82 start-page: 594 year: 1996 ident: 10.1016/j.jcms.2020.01.006_bib18 article-title: The integrated processes of hard tissue regeneration with special emphasis on fracture healing publication-title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod doi: 10.1016/S1079-2104(96)80431-8 – volume: 47 start-page: 815 year: 2019 ident: 10.1016/j.jcms.2020.01.006_bib19 article-title: Combining platelet rich fibrin with different bone graft materials: an experimental study on the histopathological and immunohistochemical aspects of bone healing publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2019.01.023 – volume: 12 start-page: 47 year: 2014 ident: 10.1016/j.jcms.2020.01.006_bib14 article-title: Teriparatide in fracture non-unions publication-title: Transl Med UniSa – volume: 19 start-page: 532 year: 2012 ident: 10.1016/j.jcms.2020.01.006_bib33 article-title: Treatment of repeated and multiple new-onset osteoporotic vertebral compression fractures with teriparatide publication-title: J Clin Neurosci doi: 10.1016/j.jocn.2011.04.048 – volume: 4 start-page: 28 year: 2015 ident: 10.1016/j.jcms.2020.01.006_bib8 article-title: Bone morphogenetic protein-7: review of signalling and efficacy in fracture healing publication-title: J Orthop Translat doi: 10.1016/j.jot.2015.08.001 – volume: 46 start-page: 1147 year: 2018 ident: 10.1016/j.jcms.2020.01.006_bib11 article-title: Comparative evaluation of various low-level laser therapies on bone healing following tooth extraction: an experimental animal study publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2018.05.012 – volume: 394 start-page: 292 year: 2014 ident: 10.1016/j.jcms.2020.01.006_bib32 article-title: In-vivo imaging of the fracture healing in medaka revealed two types of osteoclasts before and after the callus formation by osteoblasts publication-title: Dev Biol doi: 10.1016/j.ydbio.2014.08.007 – volume: 45 start-page: 1319 year: 2017 ident: 10.1016/j.jcms.2020.01.006_bib6 article-title: The epidemiological analysis of maxillofacial fractures in Italy: the experience of a single tertiary center with 1720 patients publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2017.05.011 – volume: 47 start-page: S36 issue: Suppl 1 year: 2016 ident: 10.1016/j.jcms.2020.01.006_bib12 article-title: Use of teriparatide in osteoporotic fracture patients publication-title: Injury doi: 10.1016/S0020-1383(16)30009-2 – volume: 46 start-page: 466 year: 2018 ident: 10.1016/j.jcms.2020.01.006_bib38 article-title: Effect of different doses and durations of teriparatide therapy on resolution of medication-related osteonecrosis of the jaw: a randomized, controlled preclinical study in rats publication-title: J Craniomaxillofac Surg doi: 10.1016/j.jcms.2017.12.027 – volume: 159 start-page: 179 year: 2016 ident: 10.1016/j.jcms.2020.01.006_bib24 article-title: Low level laser therapy accelerates bone healing in spinal cord injured rats publication-title: J Photochem Photobiol doi: 10.1016/j.jphotobiol.2016.03.041 – volume: 21 start-page: 1785 year: 2006 ident: 10.1016/j.jcms.2020.01.006_bib9 article-title: Change in lumbar spine BMD and vertebral fracture risk reduction in teriparatide-treated postmenopausal women with osteoporosis publication-title: J Bone Miner Res doi: 10.1359/jbmr.060802 |
| SSID | ssj0006089 |
| Score | 2.256376 |
| Snippet | This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.
A unilateral mandibular fracture, 5 mm... This study was performed to evaluate the effects of teriparatide therapy on mandibular fracture healing in a rat model.OBJECTIVEThis study was performed to... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 211 |
| SubjectTerms | Animal study Fracture Healing Mandible Teriparatide |
| Title | Histological assessment of the effects of teriparatide therapy on mandibular fracture healing: A preclinical study |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S1010518220300147 https://dx.doi.org/10.1016/j.jcms.2020.01.006 https://www.ncbi.nlm.nih.gov/pubmed/32014386 https://www.proquest.com/docview/2350910614 |
| Volume | 48 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Baden-Württemberg Complete Freedom Collection (Elsevier) customDbUrl: eissn: 1878-4119 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0006089 issn: 1010-5182 databaseCode: GBLVA dateStart: 20110101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: Elsevier ScienceDirect customDbUrl: eissn: 1878-4119 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0006089 issn: 1010-5182 databaseCode: .~1 dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: Elsevier ScienceDirect customDbUrl: eissn: 1878-4119 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0006089 issn: 1010-5182 databaseCode: ACRLP dateStart: 19950201 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: ScienceDirect Journal Collection customDbUrl: eissn: 1878-4119 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0006089 issn: 1010-5182 databaseCode: AIKHN dateStart: 19950201 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVLSH databaseName: Elsevier Journals customDbUrl: mediaType: online eissn: 1878-4119 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0006089 issn: 1010-5182 databaseCode: AKRWK dateStart: 19870101 isFulltext: true providerName: Library Specific Holdings |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lj9MwELaq5QAXBMurLFsZiRsKTWznYW5V2aqA6AUq9WbZji212k2qqj3sZX_7zjhO0UpQJI6JPIozM5n5ksx8Q8gHWdSW-SxLqlyaRMi6SCrp88Q7Lp2tdGk8ftD_sSjmS_Ftla8GZNr3wmBZZYz9XUwP0TqeGUdtjrfr9fhnhsMdAR4z8FMA-thRjuxf4NOf7n6XeRRpGIOHixNcHRtnuhqvjb1Bym6WBupOnHr05-T0N_AZktDsGXka0SOddBt8TgauOSePv2DFDw5te0F2gfYjxjOqj7SbtPUUoB6N5RvhEHyvI_6uHe3asG5p29AbbHQxWJ1KPbZQHXaOIpyEHPeZTugW1BW7KWngpn1JlrOrX9N5EscqJBbe3vaJNkYDyGOZqXlmpcgxaXObllZKw1mqZeHLzBqkpTHeCSeNEJwZ4WtMeIy_ImdN27g3hALc5Lk2TNdGC8mdLLWtSpeLWghmeTokWa9PZSPnOI6-uFZ9cdlGoQ0U2kClmQIbDMnHo8y2Y9w4uZr3ZlL93UP0U5AQTkrlR6kH3vZPufe9Jyh4DPHfim5ce4BFPCAvADtD8rpzkePuQac4ZL54-59XvSBP8KirfHtHzva7g7sEKLQ3o-DrI_Jo8vX7fHEPhB8IVw |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1NT9wwEB3BcoAL6geUBdq6EjcUbWI7ybq3FS1aCuylIHGzbMeWQJBdrXYP_HtmEicSUkulHpN4lGRmMvOSzLwBOFFF5XjIsmScK5tIVRXJWIU8CV4o78amtIE-6F_Piumt_HWX323AWdcLQ2WVMfa3Mb2J1nHPKGpztLi_H_3OaLgjwmOOfopAv9yELZljTB7A1uTicjrrA3KRNpPwaH1CArF3pi3zenBPxNrN04a9kwYf_Tk__Q1_Nnno_B3sRgDJJu01vocNX3-A7R9U9ENz2z7CsmH-iCGNmZ55k80DQ7THYgVHs4nu13J_V561nVjPbF6zJ-p1sVSgygJ1Ua2XnhGixDT3nU3YAjUWGypZQ0-7B7fnP2_OpkmcrJA4fIFbJcZagziPZ7YSmVMyp7wtXFo6pazgqVFFKDNniZnGBi-9slIKbmWoKOdxsQ-Del77A2CIOEVuLDeVNVIJr0rjxqXPZSUldyIdQtbpU7tIO07TLx51V1_2oMkGmmyg00yjDYZw2sssWtKNN1eLzky6u3sMgBpzwptSeS_1yuH-Kfet8wSNTyL9XjG1n69xkWjAF-KdIXxqXaS_etQpzZkvDv_zrF9he3pzfaWvLmaXR7BDR9pCuGMYrJZr_xmR0cp-iZ7_AnjvCwI |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Histological+assessment+of+the+effects+of+teriparatide+therapy+on+mandibular+fracture+healing%3A+A+preclinical+study&rft.jtitle=Journal+of+cranio-maxillo-facial+surgery&rft.au=Zandi%2C+Mohammad&rft.au=Dehghan%2C+Arash&rft.au=Bigonah%2C+Nemat&rft.au=Doulati%2C+Shideh&rft.date=2020-03-01&rft.issn=1878-4119&rft.eissn=1878-4119&rft.volume=48&rft.issue=3&rft.spage=211&rft_id=info:doi/10.1016%2Fj.jcms.2020.01.006&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1010-5182&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1010-5182&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1010-5182&client=summon |