A novel soluble β-1,3- d -glucan Salecan reduces adiposity and improves glucose tolerance in high-fat diet-fed mice

Salecan is a recently identified water-soluble viscous extracellular β-1,3- d -glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10 6 Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3...

Full description

Saved in:
Bibliographic Details
Published inBritish journal of nutrition Vol. 109; no. 2; pp. 254 - 262
Main Authors Zhang, Ying, Xia, Lin, Pang, Wenqiang, Wang, Tao, Chen, Peng, Zhu, Bin, Zhang, Jianfa
Format Journal Article
LanguageEnglish
Published Cambridge Cambridge University Press 28.01.2013
Subjects
Online AccessGet full text
ISSN0007-1145
1475-2662
1475-2662
DOI10.1017/S0007114512000980

Cover

Abstract Salecan is a recently identified water-soluble viscous extracellular β-1,3- d -glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10 6 Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.
AbstractList Salecan is a recently identified water-soluble viscous extracellular β-1,3-D-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10⁶ Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.
Salecan is a recently identified water-soluble viscous extracellular β-1,3- d -glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10 6 Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.
Salecan is a recently identified water-soluble viscous extracellular β-1,3-d-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10⁶Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.
Salecan is a recently identified water-soluble viscous extracellular β-1,3-D-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10⁶ Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.Salecan is a recently identified water-soluble viscous extracellular β-1,3-D-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass polymer (about 2 × 10⁶ Da) and composed of a linear chain of glucosyl residues linked through a repeat unit of seven β-(1,3) and two α-(1,3) glucosidic bonds. In the present study, we examined the effects of dietary Salecan fed at 2 and 5 % in a high-fat diet (64 % energy) in C57BL/6J mice. After 6 weeks, mice fed 2 and 5 % Salecan had significantly lower body weight, fat mass and percentage of body fat mass compared with those fed a high-fat cellulose (control) diet. Both the Salecan groups significantly and dose-dependently improved glucose tolerance, with a 9 and 26 % reduction of glucose AUC, respectively. Liver and adipose tissue weights were also significantly decreased by the Salecan treatment. Supplementation with 5 % Salecan led to lower serum TAG, total cholesterol (TC) and HDL-cholesterol (52, 18 and 19 %, respectively) and lower hepatic TAG by 56 % and TC by 22 % compared with the high-fat cellulose control group. Dietary Salecan intake caused an obvious elevation of fat in the faeces. Supplementation with Salecan disturbed bile acid-promoted emulsification and reduced the size of emulsion droplets in vitro. These results indicate that Salecan decreases fat absorption, improves glucose tolerance and has biologically important, dose-related effects on reducing high-fat diet-induced obesity.
Author Pang, Wenqiang
Zhang, Jianfa
Chen, Peng
Zhu, Bin
Zhang, Ying
Xia, Lin
Wang, Tao
Author_xml – sequence: 1
  givenname: Ying
  surname: Zhang
  fullname: Zhang, Ying
– sequence: 2
  givenname: Lin
  surname: Xia
  fullname: Xia, Lin
– sequence: 3
  givenname: Wenqiang
  surname: Pang
  fullname: Pang, Wenqiang
– sequence: 4
  givenname: Tao
  surname: Wang
  fullname: Wang, Tao
– sequence: 5
  givenname: Peng
  surname: Chen
  fullname: Chen, Peng
– sequence: 6
  givenname: Bin
  surname: Zhu
  fullname: Zhu, Bin
– sequence: 7
  givenname: Jianfa
  surname: Zhang
  fullname: Zhang, Jianfa
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26898486$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/22716316$$D View this record in MEDLINE/PubMed
BookMark eNqFkU1uFDEQhS2UiEwCB2CDvEHKAgf_tdteRhF_UqQsBtYtj7ucGLntoe0GzbU4SM5Et2YAKUSwKlv1vXK951N0lHIChF4wesEoa9-sKaUtY7JhfD4ZTZ-gFZNtQ7hS_AitljZZ-ifotJQv81Uzap6iE85bpgRTK1QvccrfIOKS47SJgO9_EPZaENxjchsnZxNe2whLHaGfHBRs-7DNJdQdtqnHYdiO84CCFzoXwDVHGG1ygEPCd-H2jnhbcR-gEg89HoKDZ-jY21jg-aGeoc_v3n66-kCub95_vLq8Jk7StpJWUCa99KpXznBoNXWCNpybxjRS8A24eS-ntfZKS6UZl8YIYZW33BjLpDhDfD93Slu7-25j7LZjGOy46xjtlgi78jDCWXS-F82-vk5QajeE4iBGmyBPpWOaL68b1v4f5ZpTKbUQM_rygE6bAfrfe_z6iRl4dQBscTb6JcJQ_nBKGy31wrE958Zcygj-L0vrRyy1DzQuVFtDTnW0If5D-RPPbbT5
CODEN BJNUAV
CitedBy_id crossref_primary_10_1016_j_cej_2020_124189
crossref_primary_10_1016_j_foodchem_2019_125632
crossref_primary_10_1088_1742_6596_1665_1_012035
crossref_primary_10_1016_j_carbpol_2017_08_133
crossref_primary_10_1016_j_foodhyd_2018_03_034
crossref_primary_10_4103_2221_1691_385569
crossref_primary_10_1016_j_aquaculture_2022_738589
crossref_primary_10_1016_j_carbpol_2016_08_077
crossref_primary_10_1016_j_carbpol_2023_121694
crossref_primary_10_2174_1381612823666170216123219
crossref_primary_10_1039_C5TB00264H
crossref_primary_10_3390_fib8010001
crossref_primary_10_1016_j_ijbiomac_2024_135261
crossref_primary_10_1016_j_jfca_2015_01_019
crossref_primary_10_1111_jpn_13163
crossref_primary_10_1016_j_taap_2017_01_007
crossref_primary_10_5762_KAIS_2015_16_6_3973
crossref_primary_10_1016_j_carbpol_2020_115920
crossref_primary_10_3390_ani9090602
crossref_primary_10_1016_j_ijbiomac_2020_07_250
crossref_primary_10_1111_fcp_12871
crossref_primary_10_1016_j_fbio_2024_104857
crossref_primary_10_1039_C6FO00606J
crossref_primary_10_3390_pharmaceutics15020373
crossref_primary_10_1016_j_carbpol_2014_01_051
crossref_primary_10_1002_cmdc_201700428
crossref_primary_10_1016_j_jnutbio_2017_04_015
crossref_primary_10_1016_j_lwt_2023_115238
crossref_primary_10_1016_j_colsurfb_2014_10_057
crossref_primary_10_1016_j_jlr_2023_100390
crossref_primary_10_1039_C9FO00627C
crossref_primary_10_1017_S000711451300442X
crossref_primary_10_1016_j_aninu_2021_04_006
crossref_primary_10_1371_journal_pone_0134799
crossref_primary_10_1016_j_foodchem_2016_12_087
crossref_primary_10_1038_s41598_020_66283_4
Cites_doi 10.1042/bj3140269
10.1016/S0144-8617(98)00099-X
10.1093/ajcn/78.2.221
10.1093/ajcn/76.2.351
10.1093/jn/117.6.1011
10.1016/j.numecd.2006.07.006
10.1016/j.foodhyd.2011.03.013
10.1592/phco.20.4.270.34882
10.1016/S0002-9343(01)00702-1
10.1016/S0092-8674(01)00240-9
10.1016/j.carbpol.2010.05.027
10.1016/0955-2863(92)90024-D
10.1093/jn/130.7.1705
10.1016/S0002-8223(21)03766-4
10.1021/jf703598j
10.1016/j.fct.2007.03.013
10.1093/jn/132.9.2494
10.1016/S0140-6736(83)90183-6
10.1038/ejcn.2010.178
10.1097/01.pap.0000249917.96509.e7
10.1007/s00253-005-1959-5
10.1016/S0022-2275(20)30116-4
10.1172/JCI10842
10.1080/03062686.1973.11904150
10.1007/978-1-4020-9173-5_11
10.1093/jn/133.2.468
10.1001/jama.295.13.1549
10.1016/S0140-6736(63)90210-1
10.1093/ajcn.70.2.208
10.1017/S0029665108006976
10.1002/mnfr.200900127
10.1093/ajcn/79.4.529
10.1093/ajcn/48.3.749
10.1016/S0008-6215(01)00023-4
10.1016/j.jhep.2009.05.017
10.1016/S0140-6736(04)16895-5
10.1016/S0278-6915(03)00046-2
10.2337/diacare.20.11.1774
10.1016/S0021-9258(18)64849-5
10.1016/j.foodhyd.2009.03.016
10.1093/jn/137.3.583
10.1016/j.fct.2011.06.050
10.1002/hep.1840200612
10.1016/0955-2863(94)90083-3
10.1002/1097-0142(197107)28:1<3::AID-CNCR2820280104>3.0.CO;2-N
10.1093/ajcn/80.5.1185
10.1093/jn/126.5.1463
10.1155/2007/95974
10.1016/0955-2863(96)00030-7
ContentType Journal Article
Copyright 2014 INIST-CNRS
Copyright_xml – notice: 2014 INIST-CNRS
DBID AAYXX
CITATION
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
ADTOC
UNPAY
DOI 10.1017/S0007114512000980
DatabaseName CrossRef
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
Unpaywall for CDI: Periodical Content
Unpaywall
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList MEDLINE
CrossRef
AGRICOLA
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: UNPAY
  name: Unpaywall
  url: https://proxy.k.utb.cz/login?url=https://unpaywall.org/
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Diet & Clinical Nutrition
EISSN 1475-2662
EndPage 262
ExternalDocumentID 10.1017/s0007114512000980
22716316
26898486
10_1017_S0007114512000980
Genre Research Support, Non-U.S. Gov't
Journal Article
GroupedDBID ---
-1D
-2P
-E.
-~6
-~X
.FH
09C
09E
0E1
0R~
23N
2WC
4.4
5GY
5RE
5VS
6J9
6PF
74X
74Y
7RV
7X2
7X7
7~V
88E
8C1
8FE
8FH
8FI
8FJ
8G5
8R4
8R5
9M5
AAAZR
AABES
AABWE
AACJH
AAFWJ
AAGFV
AAHBH
AAIKC
AAKTX
AAMNQ
AAMNW
AARAB
AASVR
AATID
AATMM
AAUIS
AAUKB
AAWTL
AAYXX
AAZAQ
ABBXD
ABFBI
ABGDZ
ABJNI
ABKKG
ABKMT
ABMWE
ABQTM
ABROB
ABUWG
ABVKB
ABVZP
ABWCF
ABXAU
ABXHF
ABZCX
ACBEK
ACBMC
ACDLN
ACGFS
ACIMK
ACPRK
ACUIJ
ACYZP
ACZBM
ACZUX
ACZWT
ADAZD
ADBBV
ADDNB
ADFEC
ADFRT
ADKIL
ADVJH
AEBAK
AEHGV
AEMTW
AENEX
AENGE
AEPLO
AEUYN
AEYHU
AFFUJ
AFKQG
AFKRA
AFLOS
AFLVW
AFRAH
AFRIC
AFUTZ
AFZFC
AGABE
AGJUD
AGLWM
AHIPN
AHLTW
AHMBA
AHQXX
AHRGI
AIGNW
AIHIV
AIOIP
AISIE
AJ7
AJCYY
AJPFC
AJQAS
AKMAY
ALMA_UNASSIGNED_HOLDINGS
ALWZO
AN0
ANPSP
AQJOH
ARABE
ATCPS
ATUCA
AUXHV
AYIQA
AZGZS
AZQEC
BAWUL
BBLKV
BENPR
BHPHI
BKEYQ
BLZWO
BMAJL
BNQBC
BPHCQ
BQFHP
BRIRG
BVXVI
C0O
CBIIA
CCPQU
CCQAD
CFAFE
CHEAL
CITATION
CJCSC
CS3
DIK
DOHLZ
DU5
DWQXO
E3Z
EBS
EJD
EX3
F5P
FYUFA
GNUQQ
GUQSH
HCIFZ
HG-
HH5
HMCUK
HST
HZ~
I.6
I.7
IH6
IOEEP
IOO
IS6
I~P
J36
J38
J3A
JHPGK
JKPOH
JQKCU
JVRFK
KCGVB
KFECR
L7B
L98
LHUNA
LW7
M-V
M0K
M1P
M2O
M7~
NAPCQ
NIKVX
O9-
OK1
OVD
P6G
PCD
PHGZM
PHGZT
PJZUB
PPXIY
PQQKQ
PROAC
PSQYO
PUEGO
Q2X
RAMDC
RCA
ROL
RR0
S6-
S6U
SAAAG
SJN
SY4
T9M
TEORI
TR2
UKHRP
UT1
UU6
WFFJZ
WH7
WOW
WQ3
WXU
WYP
Y6R
ZMEZD
ZYDXJ
~KM
-1F
-2V
-~N
.55
.GJ
354
3EH
3O-
53G
6~7
AAKNA
AANRG
AAYJJ
ABBZL
ABVFV
ABZUI
ACEJA
ACETC
ACOZI
ACRPL
ADNMO
ADOVH
ADOVT
AEBPU
AEMFK
AENCP
AFFNX
AFOSN
AGQPQ
AI.
AKZCZ
ALEEW
ANOYL
ARZZG
BCGOX
BESQT
BGHMG
BJBOZ
C1A
CAG
CCUQV
CDIZJ
CFBFF
CGQII
COF
EGQIC
I.9
IQODW
KAFGG
M8.
NMFBF
NZEOI
OHT
RIG
UAP
VH1
X7M
ZCG
ZDLDU
ZGI
ZJOSE
ZXP
~V1
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
ADTOC
UNPAY
ID FETCH-LOGICAL-c407t-73014f4f6d6c92e780c305229595432bececac888f684681249933a6fa299a143
IEDL.DBID UNPAY
ISSN 0007-1145
1475-2662
IngestDate Tue Aug 19 17:37:29 EDT 2025
Fri Sep 05 08:35:05 EDT 2025
Fri Sep 05 03:05:57 EDT 2025
Thu Apr 03 07:02:25 EDT 2025
Mon Jul 21 09:16:26 EDT 2025
Thu Apr 24 23:00:56 EDT 2025
Wed Oct 01 04:28:04 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords Obesity
β-Glucans
Salecan
Rodentia
Nutrition disorder
Tolerance
Glucose
Feeding
Glucan
Glucose tolerance
Vertebrata
Mammalia
Adiposity
Diet
Mouse
Animal
High-fat diet
Fat
Nutritional status
Language English
License https://www.cambridge.org/core/terms
CC BY 4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c407t-73014f4f6d6c92e780c305229595432bececac888f684681249933a6fa299a143
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
OpenAccessLink https://proxy.k.utb.cz/login?url=https://www.cambridge.org/core/services/aop-cambridge-core/content/view/1FE10E22B1A0F62C8FA43BE355789611/S0007114512000980a.pdf/div-class-title-a-novel-soluble-1-3-span-class-sc-d-span-glucan-salecan-reduces-adiposity-and-improves-glucose-tolerance-in-high-fat-diet-fed-mice-div.pdf
PMID 22716316
PQID 1282044833
PQPubID 23479
PageCount 9
ParticipantIDs unpaywall_primary_10_1017_s0007114512000980
proquest_miscellaneous_1825432917
proquest_miscellaneous_1282044833
pubmed_primary_22716316
pascalfrancis_primary_26898486
crossref_primary_10_1017_S0007114512000980
crossref_citationtrail_10_1017_S0007114512000980
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2013-01-28
PublicationDateYYYYMMDD 2013-01-28
PublicationDate_xml – month: 01
  year: 2013
  text: 2013-01-28
  day: 28
PublicationDecade 2010
PublicationPlace Cambridge
PublicationPlace_xml – name: Cambridge
– name: England
PublicationTitle British journal of nutrition
PublicationTitleAlternate Br J Nutr
PublicationYear 2013
Publisher Cambridge University Press
Publisher_xml – name: Cambridge University Press
References Yokoyama (S0007114512000980_ref40) 2006; 51
S0007114512000980_ref31
S0007114512000980_ref30
S0007114512000980_ref35
S0007114512000980_ref34
S0007114512000980_ref33
S0007114512000980_ref32
S0007114512000980_ref39
S0007114512000980_ref37
S0007114512000980_ref36
S0007114512000980_ref42
S0007114512000980_ref41
S0007114512000980_ref46
S0007114512000980_ref45
S0007114512000980_ref44
S0007114512000980_ref43
S0007114512000980_ref49
S0007114512000980_ref48
S0007114512000980_ref47
Asp (S0007114512000980_ref16) 1992; 46
S0007114512000980_ref50
Folch (S0007114512000980_ref24) 1957; 226
S0007114512000980_ref13
S0007114512000980_ref2
S0007114512000980_ref1
S0007114512000980_ref12
S0007114512000980_ref11
S0007114512000980_ref4
S0007114512000980_ref10
S0007114512000980_ref3
S0007114512000980_ref6
S0007114512000980_ref17
S0007114512000980_ref5
S0007114512000980_ref15
S0007114512000980_ref8
S0007114512000980_ref14
S0007114512000980_ref7
S0007114512000980_ref9
S0007114512000980_ref19
S0007114512000980_ref18
S0007114512000980_ref20
Story (S0007114512000980_ref51) 1985; 85
S0007114512000980_ref23
S0007114512000980_ref22
S0007114512000980_ref21
S0007114512000980_ref28
S0007114512000980_ref27
S0007114512000980_ref26
S0007114512000980_ref25
Madsen (S0007114512000980_ref38) 2002; 43
S0007114512000980_ref29
References_xml – ident: S0007114512000980_ref34
  doi: 10.1042/bj3140269
– ident: S0007114512000980_ref28
  doi: 10.1016/S0144-8617(98)00099-X
– ident: S0007114512000980_ref42
  doi: 10.1093/ajcn/78.2.221
– ident: S0007114512000980_ref44
  doi: 10.1093/ajcn/76.2.351
– ident: S0007114512000980_ref25
  doi: 10.1093/jn/117.6.1011
– ident: S0007114512000980_ref29
  doi: 10.1016/j.numecd.2006.07.006
– ident: S0007114512000980_ref22
  doi: 10.1016/j.foodhyd.2011.03.013
– ident: S0007114512000980_ref7
  doi: 10.1592/phco.20.4.270.34882
– ident: S0007114512000980_ref33
  doi: 10.1016/S0002-9343(01)00702-1
– ident: S0007114512000980_ref2
  doi: 10.1016/S0092-8674(01)00240-9
– volume: 46
  start-page: 31
  year: 1992
  ident: S0007114512000980_ref16
  article-title: Variation in dietary fibre, beta-glucan, starch, protein, fat and hull content of oats grown in Sweden 1987–1989
  publication-title: Eur J Clin Nutr
– ident: S0007114512000980_ref20
  doi: 10.1016/j.carbpol.2010.05.027
– ident: S0007114512000980_ref36
  doi: 10.1016/0955-2863(92)90024-D
– ident: S0007114512000980_ref49
  doi: 10.1093/jn/130.7.1705
– volume: 85
  start-page: 1105
  year: 1985
  ident: S0007114512000980_ref51
  article-title: Adherence to high-carbohydrate, high-fiber diets: long-term studies of non-obese diabetic men
  publication-title: J Am Diet Assoc
  doi: 10.1016/S0002-8223(21)03766-4
– ident: S0007114512000980_ref32
  doi: 10.1021/jf703598j
– ident: S0007114512000980_ref10
  doi: 10.1016/j.fct.2007.03.013
– ident: S0007114512000980_ref41
  doi: 10.1093/jn/132.9.2494
– ident: S0007114512000980_ref48
  doi: 10.1016/S0140-6736(83)90183-6
– ident: S0007114512000980_ref13
  doi: 10.1038/ejcn.2010.178
– ident: S0007114512000980_ref12
  doi: 10.1097/01.pap.0000249917.96509.e7
– ident: S0007114512000980_ref11
  doi: 10.1007/s00253-005-1959-5
– volume: 43
  start-page: 742
  year: 2002
  ident: S0007114512000980_ref38
  article-title: Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance
  publication-title: J Lipid Res
  doi: 10.1016/S0022-2275(20)30116-4
– ident: S0007114512000980_ref4
  doi: 10.1172/JCI10842
– ident: S0007114512000980_ref31
  doi: 10.1080/03062686.1973.11904150
– ident: S0007114512000980_ref3
  doi: 10.1007/978-1-4020-9173-5_11
– ident: S0007114512000980_ref9
  doi: 10.1093/jn/133.2.468
– ident: S0007114512000980_ref1
  doi: 10.1001/jama.295.13.1549
– ident: S0007114512000980_ref18
  doi: 10.1016/S0140-6736(63)90210-1
– ident: S0007114512000980_ref14
  doi: 10.1093/ajcn.70.2.208
– volume: 51
  start-page: 16
  year: 2006
  ident: S0007114512000980_ref40
  article-title: Soluble fibers prevent insulin resistance in hamsters fed high saturated fat diets
  publication-title: Cereal Foods World
– ident: S0007114512000980_ref6
  doi: 10.1017/S0029665108006976
– ident: S0007114512000980_ref39
  doi: 10.1002/mnfr.200900127
– ident: S0007114512000980_ref8
  doi: 10.1093/ajcn/79.4.529
– ident: S0007114512000980_ref47
  doi: 10.1093/ajcn/48.3.749
– ident: S0007114512000980_ref27
  doi: 10.1016/S0008-6215(01)00023-4
– ident: S0007114512000980_ref37
  doi: 10.1016/j.jhep.2009.05.017
– ident: S0007114512000980_ref46
  doi: 10.1016/S0140-6736(04)16895-5
– ident: S0007114512000980_ref50
  doi: 10.1016/S0278-6915(03)00046-2
– ident: S0007114512000980_ref17
  doi: 10.2337/diacare.20.11.1774
– volume: 226
  start-page: 497
  year: 1957
  ident: S0007114512000980_ref24
  article-title: A simple method for the isolation and purification of total lipides from animal tissues
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(18)64849-5
– ident: S0007114512000980_ref23
  doi: 10.1016/j.foodhyd.2009.03.016
– ident: S0007114512000980_ref43
  doi: 10.1093/jn/137.3.583
– ident: S0007114512000980_ref21
  doi: 10.1016/j.fct.2011.06.050
– ident: S0007114512000980_ref15
  doi: 10.1002/hep.1840200612
– ident: S0007114512000980_ref35
  doi: 10.1016/0955-2863(94)90083-3
– ident: S0007114512000980_ref30
  doi: 10.1002/1097-0142(197107)28:1<3::AID-CNCR2820280104>3.0.CO;2-N
– ident: S0007114512000980_ref45
  doi: 10.1093/ajcn/80.5.1185
– ident: S0007114512000980_ref19
  doi: 10.1093/jn/126.5.1463
– ident: S0007114512000980_ref5
  doi: 10.1155/2007/95974
– ident: S0007114512000980_ref26
  doi: 10.1016/0955-2863(96)00030-7
SSID ssj0008109
Score 2.2581031
Snippet Salecan is a recently identified water-soluble viscous extracellular β-1,3- d -glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass...
Salecan is a recently identified water-soluble viscous extracellular β-1,3-D-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass...
Salecan is a recently identified water-soluble viscous extracellular β-1,3-d-glucan polysaccharide from an Agrobacterium species. It is a high-molecular-mass...
SourceID unpaywall
proquest
pubmed
pascalfrancis
crossref
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage 254
SubjectTerms absorption
Adiposity
Agrobacterium
Animals
Anti-Obesity Agents - administration & dosage
Anti-Obesity Agents - chemistry
Anti-Obesity Agents - therapeutic use
beta-Glucans - administration & dosage
beta-Glucans - chemistry
beta-Glucans - therapeutic use
bile
Biological and medical sciences
blood serum
Cell Size
cellulose
Diet, High-Fat - adverse effects
Dietary Fats - analysis
Dietary Fats - metabolism
Dietary Supplements
droplets
emulsifying
Emulsifying Agents - administration & dosage
Emulsifying Agents - chemistry
Emulsifying Agents - therapeutic use
emulsions
energy
fat body
feces
Feces - chemistry
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
glucose
Glucose Intolerance - etiology
Glucose Intolerance - prevention & control
glucose tolerance
high density lipoprotein cholesterol
high fat diet
Intestinal Absorption
Intra-Abdominal Fat - pathology
Lipid Metabolism
liver
Liver - metabolism
Liver - pathology
Mice
Mice, Inbred C57BL
obesity
Obesity - etiology
Obesity - metabolism
Obesity - pathology
Obesity - prevention & control
Organ Size
polymers
Solubility
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Weight Gain
Title A novel soluble β-1,3- d -glucan Salecan reduces adiposity and improves glucose tolerance in high-fat diet-fed mice
URI https://www.ncbi.nlm.nih.gov/pubmed/22716316
https://www.proquest.com/docview/1282044833
https://www.proquest.com/docview/1825432917
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/1FE10E22B1A0F62C8FA43BE355789611/S0007114512000980a.pdf/div-class-title-a-novel-soluble-1-3-span-class-sc-d-span-glucan-salecan-reduces-adiposity-and-improves-glucose-tolerance-in-high-fat-diet-fed-mice-div.pdf
UnpaywallVersion publishedVersion
Volume 109
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVFSB
  databaseName: Free Full-Text Journals in Chemistry
  customDbUrl:
  eissn: 1475-2662
  dateEnd: 20241002
  omitProxy: true
  ssIdentifier: ssj0008109
  issn: 1475-2662
  databaseCode: HH5
  dateStart: 19470101
  isFulltext: true
  titleUrlDefault: http://abc-chemistry.org/
  providerName: ABC ChemistRy
– providerCode: PRVBFR
  databaseName: Free Medical Journals
  customDbUrl:
  eissn: 1475-2662
  dateEnd: 20241002
  omitProxy: true
  ssIdentifier: ssj0008109
  issn: 1475-2662
  databaseCode: DIK
  dateStart: 19470101
  isFulltext: true
  titleUrlDefault: http://www.freemedicaljournals.com
  providerName: Flying Publisher
– providerCode: PRVPQU
  databaseName: Health & Medical Collection
  customDbUrl:
  eissn: 1475-2662
  dateEnd: 20241002
  omitProxy: true
  ssIdentifier: ssj0008109
  issn: 1475-2662
  databaseCode: 7X7
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  eissn: 1475-2662
  dateEnd: 20241002
  omitProxy: true
  ssIdentifier: ssj0008109
  issn: 1475-2662
  databaseCode: BENPR
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Public Health Database
  customDbUrl:
  eissn: 1475-2662
  dateEnd: 20241002
  omitProxy: true
  ssIdentifier: ssj0008109
  issn: 1475-2662
  databaseCode: 8C1
  dateStart: 20010101
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/publichealth
  providerName: ProQuest
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw7V3db9MwEPe27gEQ4vujAyojIR6Aa2MncRzx1I1WExLVBEwaT5WT2FJFlVZrOjT-LP4Q_ibu8gVl0yTeeUnkxlF-zeXufrbPd4y9UEhSdRpKkDLTEGQ4YE006qNQSO-dC0M_oY3CHybq8Dh4fxKebG_tNXthKKyyzXFQruSX9dFWteIMzGIJ7XUor1FMNxroAU2lD8R4JLyRlPti6I2VPNDjYeDvj9CrRjpWQtDWYPSqVJ-WNqnE2jP9ZeYG2ewMUuKrUAoJDOSLMzsH-gASbAvwAVU8rzutUsiqNkWW42mF5pzOp5Rw1a7AZLMy6uocTJ7BrJwgwJ_rOHQoFnNLhTMszHKgxMTgTAHZzBbgbAZUiR5bZwRth-0qWjzrsN3jydHwS8Xn8W2KsgKzCCIKU1OyWbIVZYbUzf-44XRvLs0K5e-qwh2XMesb7No6X5rzb2Y-_8Pbjm9vvW3kVAXZfO2vi6Sffv8rheV_QV4myDvsVj3I4MPKKtxl2za_x7rvsDt_yetMsHM-aQox3GenQ17i5zV-_vMHiDc-ZDVe_qnCy2u8vMXLES9v8PIaL2_x8lnOG7y8wcsJ7wN2PB59PjiEuhoHpDjoL4BcQeACpzKVxtJG2kvRV1A1-DgMfIm2AHGkWmunkNMSb0Tq6xvlDDIeg7T8Ievki9w-ZtyXwrkYfbSTSZCaMIl8K4TTYeIHmbNel3nN5zpN61T1VDFlPq1iEqPpBeF32av2lmWVp-Wqzr0NHWjvkErHOtCqy543SjFFc0traCa3i_VqinROekGgff-KPjTr4stYRF32qNKo30-QEY6ABD7hdatiFwBf0N-9f-r9hF2XZdEWAVI_ZZ3idG2fIXUukh7biU4iPOoD0WO7-6PJ0cdebVd-AcaNwbw
linkProvider Unpaywall
linkToUnpaywall http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw7V3db9MwEPdG9wAI8f3RAZOREA-Ma2MncRzx1I1WExIVElQaT5WT2FJFlVZtWjT-LP4Q_ibu8gVj0yTeeYqcOMovudzdz_b5jrGXCkmqTkMJUmYaggwHrIlGfRQK6b1zYegntFH4w1idTIL3p-Hp7s5-sxeGwirbHAflSn5ZH21dK07fLJbQXofyGsV0o4Hu01R6X4yGwhtKeSQG3kjJYz0aBP7REL1qpGMlBG0NRq9K9Wlpk0qsPdNbZq6fzbaQEl-FUkhgIF9s7RzoB0iwLcAHVPG87rROIavaFFmOhzWaczquKOGqXYPJZmXU1RmYPINZOUGAp-s4dCgWc0uFMyzMcqDExOBMAdnMFuBsBlSJHltbgnaN7SlaPOuwvcn44-BLxefxa4qyArMIIgpTU7JZshVlhtTz73jO6d5amjXK31WFOy5j1jfZ9U2-NGffzHz-h7cd3dl528ipCrL52tsUSS_9_lcKy_-CvEyQd9ntepDBB5VVuMd2bX6fdd9hd_6K15lg53zcFGJ4wFYDXuLnNX7-8weINz5kNV7-qcLLa7y8xcsRL2_w8hovb_HyWc4bvLzBywnvQzYZDT8fn0BdjQNSHPQXQK4gcIFTmUpjaSPtpegrqBp8HAa-RFuAOFKttVPIaYk3IvX1jXIGGY9BWv6IdfJFbp8w7kvhXIw-2skkSE2YRL4Vwukw8YPMWa_LvOZ3naZ1qnqqmDKfVjGJ0fSC8LvsdXvLssrTclXng3M60N4hlY51oFWXvWiUYormltbQTG4Xm_UU6Zz0gkD7_hV9aNbFl7GIuuxxpVG_nyAjHAEJfMJhq2IXAF_Q3_1_6v2U3ZBl0RYBUj9jnWK1sc-ROhfJQW1DfgHPp75u
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+novel+soluble+%CE%B2-1%2C3-D-glucan+Salecan+reduces+adiposity+and+improves+glucose+tolerance+in+high-fat+diet-fed+mice&rft.jtitle=British+journal+of+nutrition&rft.au=YING+ZHANG&rft.au=LIN+XIA&rft.au=WENQIANG+PANG&rft.au=TAO+WANG&rft.date=2013-01-28&rft.pub=Cambridge+University+Press&rft.issn=0007-1145&rft.volume=109&rft.issue=2&rft.spage=254&rft.epage=262&rft_id=info:doi/10.1017%2FS0007114512000980&rft.externalDBID=n%2Fa&rft.externalDocID=26898486
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0007-1145&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0007-1145&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0007-1145&client=summon