Treatment of High-Risk Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia in Adolescents and Adults According to Early Cytologic Response and Minimal Residual Disease After Consolidation Assessed by Flow Cytometry: Final Results of the PETHEMA ALL-AR-03 Trial - Ribera, Josep-Maria; Oriol, Albert; Morgades, Mireia; Montesinos, Pau; Sarrà, Josep; González-Campos, José; Brunet, Salut; Tormo, Mar; Fernández-Abellán, Pascual; Guàrdia, Ramon; Bernal, María-Teresa; Esteve, Jordi; et al. (Journal of clinical oncology, 2014)
Keywords: Adolescent; Adult; Age Factors; Consolidation Chemotherapy - adverse effects; Consolidation Chemotherapy - mortality; Disease-Free Survival; Female; Flow Cytometry; Genetic Predisposition to Disease; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Logistic Models; Maintenance Chemotherapy; Male; Middle Aged; Multivariate Analysis; Neoplasm, Residual; Patient Selection; Phenotype; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality; Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Spain; Time Factors; Treatment Outcome; Young Adult; Spain