Glucose Control and the Effect of Empagliflozin on Kidney Outcomes in Type 2 Diabetes: An Analysis From the EMPA-REG OUTCOME Trial
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Published in | American journal of kidney diseases Vol. 74; no. 5; pp. 713 - 715 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.11.2019
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Subjects | |
Online Access | Get full text |
ISSN | 0272-6386 1523-6838 1523-6838 |
DOI | 10.1053/j.ajkd.2019.03.432 |
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Author | Wanner, Christoph Koitka-Weber, Audrey Inzucchi, Silvio E. von Eynatten, Maximilian Cooper, Mark E. Zinman, Bernard Hantel, Stefan |
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Author_xml | – sequence: 1 givenname: Mark E. surname: Cooper fullname: Cooper, Mark E. email: mark.cooper@monash.edu organization: Department of Diabetes, Central Clinical School, Monash University, Melbourne, Australia – sequence: 2 givenname: Silvio E. surname: Inzucchi fullname: Inzucchi, Silvio E. organization: Section of Endocrinology, Yale School of Medicine, New Haven, CT – sequence: 3 givenname: Bernard surname: Zinman fullname: Zinman, Bernard organization: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Canada – sequence: 4 givenname: Stefan surname: Hantel fullname: Hantel, Stefan organization: Boehringer Ingelheim International GmbH, Biberach – sequence: 5 givenname: Maximilian surname: von Eynatten fullname: von Eynatten, Maximilian organization: Boehringer Ingelheim International GmbH, Ingelheim – sequence: 6 givenname: Christoph surname: Wanner fullname: Wanner, Christoph organization: Department of Medicine, Würzburg University Clinic, Würzburg, Germany – sequence: 7 givenname: Audrey surname: Koitka-Weber fullname: Koitka-Weber, Audrey organization: Department of Diabetes, Central Clinical School, Monash University, Melbourne, Australia |
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Cites_doi | 10.1038/nrneph.2013.251 10.1038/ki.2014.128 10.1056/NEJMoa1504720 10.1681/ASN.2012070718 10.1016/S2213-8587(17)30182-1 10.1001/jama.2016.10924 10.1056/NEJMoa1515920 10.1681/ASN.2016030278 |
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References | Cherney, Zinman, Inzucchi (bib8) 2017; 5 Wanner, Inzucchi, Lachin (bib6) 2016; 375 Heerspink, Desai, Jardine, Balis, Meininger, Perkovic (bib7) 2017; 28 Zinman, Wanner, Lachin (bib5) 2015; 373 Molitch, Adler, Flyvbjerg (bib3) 2015; 87 Roscioni, Heerspink, de Zeeuw (bib4) 2014; 10 Afkarian, Zelnick, Hall (bib1) 2016; 316 Afkarian, Sachs, Kestenbaum (bib2) 2013; 24 Molitch (10.1053/j.ajkd.2019.03.432_bib3) 2015; 87 Wanner (10.1053/j.ajkd.2019.03.432_bib6) 2016; 375 Afkarian (10.1053/j.ajkd.2019.03.432_bib1) 2016; 316 Roscioni (10.1053/j.ajkd.2019.03.432_bib4) 2014; 10 Cherney (10.1053/j.ajkd.2019.03.432_bib8) 2017; 5 Heerspink (10.1053/j.ajkd.2019.03.432_bib7) 2017; 28 Afkarian (10.1053/j.ajkd.2019.03.432_bib2) 2013; 24 Zinman (10.1053/j.ajkd.2019.03.432_bib5) 2015; 373 |
References_xml | – volume: 373 start-page: 2117 year: 2015 end-page: 2128 ident: bib5 article-title: Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes publication-title: N Engl J Med – volume: 28 start-page: 368 year: 2017 end-page: 375 ident: bib7 article-title: Canagliflozin slows progression of renal function decline independently of glycemic effects publication-title: J Am Soc Nephrol – volume: 10 start-page: 77 year: 2014 end-page: 87 ident: bib4 article-title: The effect of RAAS blockade on the progression of diabetic nephropathy publication-title: Nat Rev Nephrol – volume: 24 start-page: 302 year: 2013 end-page: 308 ident: bib2 article-title: Kidney disease and increased mortality risk in type 2 diabetes publication-title: J Am Soc Nephrol – volume: 316 start-page: 602 year: 2016 end-page: 610 ident: bib1 article-title: Clinical manifestations of kidney disease among US adults with diabetes, 1988-2014 publication-title: JAMA – volume: 5 start-page: 610 year: 2017 end-page: 621 ident: bib8 article-title: Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial publication-title: Lancet Diabetes Endocrinol – volume: 375 start-page: 323 year: 2016 end-page: 334 ident: bib6 article-title: Empagliflozin and progression of kidney disease in type 2 diabetes publication-title: N Engl J Med – volume: 87 start-page: 20 year: 2015 end-page: 30 ident: bib3 article-title: Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes publication-title: Kidney Int – volume: 10 start-page: 77 issue: 2 year: 2014 ident: 10.1053/j.ajkd.2019.03.432_bib4 article-title: The effect of RAAS blockade on the progression of diabetic nephropathy publication-title: Nat Rev Nephrol doi: 10.1038/nrneph.2013.251 – volume: 87 start-page: 20 issue: 1 year: 2015 ident: 10.1053/j.ajkd.2019.03.432_bib3 article-title: Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes publication-title: Kidney Int doi: 10.1038/ki.2014.128 – volume: 373 start-page: 2117 issue: 22 year: 2015 ident: 10.1053/j.ajkd.2019.03.432_bib5 article-title: Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa1504720 – volume: 24 start-page: 302 issue: 2 year: 2013 ident: 10.1053/j.ajkd.2019.03.432_bib2 article-title: Kidney disease and increased mortality risk in type 2 diabetes publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2012070718 – volume: 5 start-page: 610 issue: 8 year: 2017 ident: 10.1053/j.ajkd.2019.03.432_bib8 article-title: Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial publication-title: Lancet Diabetes Endocrinol doi: 10.1016/S2213-8587(17)30182-1 – volume: 316 start-page: 602 issue: 6 year: 2016 ident: 10.1053/j.ajkd.2019.03.432_bib1 article-title: Clinical manifestations of kidney disease among US adults with diabetes, 1988-2014 publication-title: JAMA doi: 10.1001/jama.2016.10924 – volume: 375 start-page: 323 issue: 4 year: 2016 ident: 10.1053/j.ajkd.2019.03.432_bib6 article-title: Empagliflozin and progression of kidney disease in type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa1515920 – volume: 28 start-page: 368 issue: 1 year: 2017 ident: 10.1053/j.ajkd.2019.03.432_bib7 article-title: Canagliflozin slows progression of renal function decline independently of glycemic effects publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2016030278 |
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SubjectTerms | Benzhydryl Compounds - administration & dosage Blood Glucose - metabolism Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetic Nephropathies - epidemiology Diabetic Nephropathies - etiology Diabetic Nephropathies - prevention & control Dose-Response Relationship, Drug Global Health Glucosides - administration & dosage Humans Prevalence Randomized Controlled Trials as Topic Risk Factors Sodium-Glucose Transporter 2 Inhibitors - administration & dosage Treatment Outcome |
Title | Glucose Control and the Effect of Empagliflozin on Kidney Outcomes in Type 2 Diabetes: An Analysis From the EMPA-REG OUTCOME Trial |
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