Spectral-Domain Optical Coherence Tomography of Sympathetic Ophthalmia With Dalen–Fuchs Nodules

• Published in: Ophthalmic surgery, lasers & imaging Vol. 45; no. 6; pp. 610 - 612
• Main Authors: Muakkassa, Nora W., Witkin, Andre J.
• Format: Journal Article
• Language: English
• Published: Thorofare, NJ SLACK Incorporated 01.11.2014; SLACK INCORPORATED
• Subjects: Aged, 80 and over; Domains; Eye diseases; Eye Injuries, Penetrating - pathology; Fluorescein Angiography; Glucocorticoids - therapeutic use; Humans; Lesions; Male; Medical imaging; Nodules; Ophthalmia, Sympathetic - diagnosis; Ophthalmia, Sympathetic - drug therapy; Ophthalmology; Optical Coherence Tomography; Prednisone - therapeutic use; Retinal Photoreceptor Cell Inner Segment - pathology; Retinal Photoreceptor Cell Outer Segment - pathology; Retinal Pigment Epithelium - pathology; Segments; Tomography; Tomography, Optical Coherence; Triamcinolone Acetonide - therapeutic use
• ISSN: 2325-8160; 2325-8179; 2325-8179
• DOI: 10.3928/23258160-20141008-01

The authors present a case of sympathetic ophthalmia with Dalen–Fuchs nodules visualized with spectral-domain optical coherence tomography (SD-OCT). An 84-year-old man presented with floaters and decreased vision 25 years after penetrating trauma to the fellow eye. Examination revealed vitritis and subretinal lesions consistent with Dalen–Fuchs nodules. He was diagnosed with sympathetic ophthalmia after a negative systemic work-up. SD-OCT revealed hyper-reflective lesions at the level of the retinal pigment epithelium with disruption of the inner segment/outer segment (IS/OS) junction. Treatment resulted in clinical improvement and disappearance of Dalen–Fuchs nodules on SD-OCT; however, photoreceptor and retinal pigment epithelial disruptions persisted 5 months after treatment was initiated. [Ophthalmic Surg Lasers Imaging Retina. 2014;45:610–612.]