Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock‐In Mouse Model of Amyloidopathy - Dumont, Julie R.; Sheppard, Paul A. S.; Fodor, Chris; Coto, M. Alexander; Yang, Sabrina; Saito, Takashi; Saido, Takaomi C.; Rylett, R. Jane; Prado, Marco A. M.; Bussey, Timothy J.; Saksida, Lisa M.; Prado, Vania F. (Genes, brain and behavior, 2025)
Keywords: Alzheimer Disease - genetics; Alzheimer's disease; Amyloid beta-Protein Precursor - genetics; Amyloid beta-Protein Precursor - metabolism; Amyloid precursor protein; Animal models; Animals; APP; Cognition - physiology; Cognitive ability; Cognitive Flexibility; Disease Models, Animal; executive dysfunction; extinction; Female; Flexibility; Gene Knock-In Techniques; Interactive computer systems; Learning - physiology; Male; Mice; Mice, Transgenic; Mutation; Neurodegenerative diseases; Neurofibrillary tangles; Original; pairwise visual discrimination; Plaque, Amyloid; Protein structure; reversal learning; Senile plaques; Tau protein; Visual discrimination; Visual stimuli; reversal learning; APP; executive dysfunction; extinction; pairwise visual discrimination