Influence of prestroke glycemic status on outcomes by age in patients with acute ischemic stroke and diabetes mellitus
Background This study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM). Methods This study analyzed prospective multicenter data from patients with AIS and...
Saved in:
| Published in | European journal of neurology Vol. 32; no. 1; pp. e70004 - n/a |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
John Wiley & Sons, Inc
01.01.2025
John Wiley and Sons Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1351-5101 1468-1331 1468-1331 |
| DOI | 10.1111/ene.70004 |
Cover
| Abstract | Background
This study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM).
Methods
This study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%–7.0%, 7.1%–8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56–65 years, 66–75 years, 76–85 years, and >85 years. The primary outcome was 1‐year composite of stroke, MI, and all‐cause mortality. The modifying effect of age on the relationships between HbA1c and 1‐year primary outcome was explored by Cox proportional hazards model.
Results
A total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1‐year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13–1.70]). For patients aged 56–65 and 66–75, the highest HRs were observed for an HbA1c of 7.1–8.0% (aHRs; 1.21 [1.01–1.46] and 1.22 [1.05–1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98–2.19]). The HbA1c 8.0% showed evident age‐dependent heterogeneity in the post hoc HR plots.
Conclusion
Our study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1‐year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age‐stratified, heterogeneous associations between admission HbA1c and 1‐year vascular outcomes in patients with AIS and diabetes. |
|---|---|
| AbstractList | BackgroundThis study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM).MethodsThis study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%–7.0%, 7.1%–8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56–65 years, 66–75 years, 76–85 years, and >85 years. The primary outcome was 1‐year composite of stroke, MI, and all‐cause mortality. The modifying effect of age on the relationships between HbA1c and 1‐year primary outcome was explored by Cox proportional hazards model.ResultsA total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1‐year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13–1.70]). For patients aged 56–65 and 66–75, the highest HRs were observed for an HbA1c of 7.1–8.0% (aHRs; 1.21 [1.01–1.46] and 1.22 [1.05–1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98–2.19]). The HbA1c 8.0% showed evident age‐dependent heterogeneity in the post hoc HR plots.ConclusionOur study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1‐year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age‐stratified, heterogeneous associations between admission HbA1c and 1‐year vascular outcomes in patients with AIS and diabetes. Background This study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM). Methods This study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%–7.0%, 7.1%–8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56–65 years, 66–75 years, 76–85 years, and >85 years. The primary outcome was 1‐year composite of stroke, MI, and all‐cause mortality. The modifying effect of age on the relationships between HbA1c and 1‐year primary outcome was explored by Cox proportional hazards model. Results A total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1‐year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13–1.70]). For patients aged 56–65 and 66–75, the highest HRs were observed for an HbA1c of 7.1–8.0% (aHRs; 1.21 [1.01–1.46] and 1.22 [1.05–1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98–2.19]). The HbA1c 8.0% showed evident age‐dependent heterogeneity in the post hoc HR plots. Conclusion Our study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1‐year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age‐stratified, heterogeneous associations between admission HbA1c and 1‐year vascular outcomes in patients with AIS and diabetes. This study aimed to explore the association between admission HbA1c and the risk of 1-year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM). This study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%-7.0%, 7.1%-8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56-65 years, 66-75 years, 76-85 years, and >85 years. The primary outcome was 1-year composite of stroke, MI, and all-cause mortality. The modifying effect of age on the relationships between HbA1c and 1-year primary outcome was explored by Cox proportional hazards model. A total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1-year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13-1.70]). For patients aged 56-65 and 66-75, the highest HRs were observed for an HbA1c of 7.1-8.0% (aHRs; 1.21 [1.01-1.46] and 1.22 [1.05-1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98-2.19]). The HbA1c 8.0% showed evident age-dependent heterogeneity in the post hoc HR plots. Our study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1-year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age-stratified, heterogeneous associations between admission HbA1c and 1-year vascular outcomes in patients with AIS and diabetes. This study aimed to explore the association between admission HbA1c and the risk of 1-year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM).BACKGROUNDThis study aimed to explore the association between admission HbA1c and the risk of 1-year vascular outcomes stratified by age group in patients with acute ischemic stroke (AIS) and diabetes mellitus (DM).This study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%-7.0%, 7.1%-8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56-65 years, 66-75 years, 76-85 years, and >85 years. The primary outcome was 1-year composite of stroke, MI, and all-cause mortality. The modifying effect of age on the relationships between HbA1c and 1-year primary outcome was explored by Cox proportional hazards model.METHODSThis study analyzed prospective multicenter data from patients with AIS and DM. Admission HbA1C were categorized as:≤6.0%, 6.1%-7.0%, 7.1%-8.0%, and >8.0%. Age was analyzed in categories:≤55 years, 56-65 years, 66-75 years, 76-85 years, and >85 years. The primary outcome was 1-year composite of stroke, MI, and all-cause mortality. The modifying effect of age on the relationships between HbA1c and 1-year primary outcome was explored by Cox proportional hazards model.A total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1-year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13-1.70]). For patients aged 56-65 and 66-75, the highest HRs were observed for an HbA1c of 7.1-8.0% (aHRs; 1.21 [1.01-1.46] and 1.22 [1.05-1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98-2.19]). The HbA1c 8.0% showed evident age-dependent heterogeneity in the post hoc HR plots.RESULTSA total of 16,077 patients (age 69.0 ± 12.4 years; 59.4% males) were analyzed in this study. Among patients ≤55 years, the hazard ratio (HR) of the 1-year primary outcomes increased with an HbA1C > 8.0% (adjusted HR 1.39[1.13-1.70]). For patients aged 56-65 and 66-75, the highest HRs were observed for an HbA1c of 7.1-8.0% (aHRs; 1.21 [1.01-1.46] and 1.22 [1.05-1.41], respectively). In the 85+ age group, the highest HR occurred for HbA1c ≤ 6.0% (aHR 1.47 [0.98-2.19]). The HbA1c 8.0% showed evident age-dependent heterogeneity in the post hoc HR plots.Our study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1-year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age-stratified, heterogeneous associations between admission HbA1c and 1-year vascular outcomes in patients with AIS and diabetes.CONCLUSIONOur study revealed that in patients with AIS and diabetes under 55, higher admission hbA1c was associated with an increased risk of the 1-year primary outcome, while in patients aged over 85, lower HbA1c value (≤6.0%) may be associated with an increased risk of vascular events. The results of our study suggest the age-stratified, heterogeneous associations between admission HbA1c and 1-year vascular outcomes in patients with AIS and diabetes. |
| Author | Lee, Jun Hong, Keun‐Sik Lee, Ji Sung Kim, Chulho Lee, Soo Joo Park, Jong‐Moo Yum, Kyu Sun Kim, Joon‐Tae Kim, Beom Joon Kang, Kyusik Kim, Jae Guk Saver, Jeffrey L. Cho, Yong‐Jin Lee, Byung‐Chul Kim, Wook‐Joo Shin, Dong‐Ick Oh, Mi Sun Kwon, Jee‐Hyun Park, Man‐Seok Yu, Kyung‐Ho Lee, Sang‐Hwa Kim, Hyunsoo Park, Hong‐Kyun Lee, Juneyoung Cha, Jae‐Kwan Choi, Jay Chol Kang, Jihoon Lee, Kyungbok Lee, Keon‐Joo Kim, Dong‐Eog Bae, Hee‐Joon Kim, Dae‐Hyun Sohn, Sung Il Park, Kwang‐Yeol Park, Tai Hwan Ryu, Wi‐Sun Hong, Jeong‐Ho |
| AuthorAffiliation | 10 Department of Neurology Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine Seoul Korea 9 Department of Neurology Seoul Medical Center Seoul Korea 14 Department of Neurology Dongguk University Ilsan Hospital Goyang Korea 23 Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine University of California Los Angeles California USA 16 Department of Neurology Ulsan University College of Medicine Ulsan Korea 12 Department of Neurology Ilsan Paik Hospital, Inje University Goyang Korea 5 Department of Neurology Uijeongbu Eulji Medical Center, Eulji University School of Medicine Uijeongbu‐si Korea 15 Department of Neurology Jeju National University Hospital, Jeju National University School of Medicine Jeju Korea 13 Department of Neurology Hallym University Sacred Heart Hospital Anyang Korea 17 Department of Neurology Chungbuk National University Hospital Cheongju Korea 18 Department of Neurology Keimyung University Dongsan Medical Ce |
| AuthorAffiliation_xml | – name: 7 Department of Neurology, Daejeon Eulji Medical Center Eulji University School of Medicine Daejeon Korea – name: 12 Department of Neurology Ilsan Paik Hospital, Inje University Goyang Korea – name: 15 Department of Neurology Jeju National University Hospital, Jeju National University School of Medicine Jeju Korea – name: 4 Department of Neurology Korea University Guro Hospital Seoul Korea – name: 3 Department of Neurology Seoul National University College of Medicine, Seoul National University Bundang Hospital Seongnam Korea – name: 20 Artificial Intelligence Research Center, JLK Inc. Seoul Korea – name: 13 Department of Neurology Hallym University Sacred Heart Hospital Anyang Korea – name: 1 Department of Neurology Chonnam National University Hospital, Chonnam National University Medical School Gwangju Korea – name: 14 Department of Neurology Dongguk University Ilsan Hospital Goyang Korea – name: 5 Department of Neurology Uijeongbu Eulji Medical Center, Eulji University School of Medicine Uijeongbu‐si Korea – name: 17 Department of Neurology Chungbuk National University Hospital Cheongju Korea – name: 21 Department of Neurology Chung‐Ang University College of Medicine, Chung‐Ang University Hospital Seoul Korea – name: 11 Department of Neurology Yeungnam University Hospital Daegu Korea – name: 18 Department of Neurology Keimyung University Dongsan Medical Center Daegu Korea – name: 16 Department of Neurology Ulsan University College of Medicine Ulsan Korea – name: 19 Department of Neurology Hallym University Chuncheon Sacred Heart Hospital Chuncheon‐si Gangwon‐do Korea – name: 22 Department of Biostatistics Korea University College of Medicine Seoul Korea – name: 10 Department of Neurology Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine Seoul Korea – name: 2 Clinical Research Center Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine Seoul Korea – name: 23 Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine University of California Los Angeles California USA – name: 6 Department of Neurology Nowon Eulji Medical Center, Eulji University School of Medicine Seoul Korea – name: 8 Department of Neurology Dong‐A University Hospital Busan Korea – name: 9 Department of Neurology Seoul Medical Center Seoul Korea |
| Author_xml | – sequence: 1 givenname: Joon‐Tae orcidid: 0000-0003-4028-8339 surname: Kim fullname: Kim, Joon‐Tae email: alldelight2@jnu.ac.kr organization: Chonnam National University Hospital, Chonnam National University Medical School – sequence: 2 givenname: Ji Sung surname: Lee fullname: Lee, Ji Sung organization: Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine – sequence: 3 givenname: Hyunsoo surname: Kim fullname: Kim, Hyunsoo organization: Chonnam National University Hospital, Chonnam National University Medical School – sequence: 4 givenname: Beom Joon orcidid: 0000-0002-2719-3012 surname: Kim fullname: Kim, Beom Joon organization: Seoul National University College of Medicine, Seoul National University Bundang Hospital – sequence: 5 givenname: Jihoon surname: Kang fullname: Kang, Jihoon organization: Seoul National University College of Medicine, Seoul National University Bundang Hospital – sequence: 6 givenname: Keon‐Joo surname: Lee fullname: Lee, Keon‐Joo organization: Korea University Guro Hospital – sequence: 7 givenname: Jong‐Moo surname: Park fullname: Park, Jong‐Moo organization: Uijeongbu Eulji Medical Center, Eulji University School of Medicine – sequence: 8 givenname: Kyusik surname: Kang fullname: Kang, Kyusik organization: Nowon Eulji Medical Center, Eulji University School of Medicine – sequence: 9 givenname: Soo Joo surname: Lee fullname: Lee, Soo Joo organization: Eulji University School of Medicine – sequence: 10 givenname: Jae Guk surname: Kim fullname: Kim, Jae Guk organization: Eulji University School of Medicine – sequence: 11 givenname: Jae‐Kwan surname: Cha fullname: Cha, Jae‐Kwan organization: Dong‐A University Hospital – sequence: 12 givenname: Dae‐Hyun surname: Kim fullname: Kim, Dae‐Hyun organization: Dong‐A University Hospital – sequence: 13 givenname: Tai Hwan surname: Park fullname: Park, Tai Hwan organization: Seoul Medical Center – sequence: 14 givenname: Kyungbok surname: Lee fullname: Lee, Kyungbok organization: Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine – sequence: 15 givenname: Jun surname: Lee fullname: Lee, Jun organization: Yeungnam University Hospital – sequence: 16 givenname: Keun‐Sik surname: Hong fullname: Hong, Keun‐Sik organization: Ilsan Paik Hospital, Inje University – sequence: 17 givenname: Yong‐Jin surname: Cho fullname: Cho, Yong‐Jin organization: Ilsan Paik Hospital, Inje University – sequence: 18 givenname: Hong‐Kyun orcidid: 0000-0002-8120-2469 surname: Park fullname: Park, Hong‐Kyun organization: Ilsan Paik Hospital, Inje University – sequence: 19 givenname: Byung‐Chul surname: Lee fullname: Lee, Byung‐Chul organization: Hallym University Sacred Heart Hospital – sequence: 20 givenname: Kyung‐Ho surname: Yu fullname: Yu, Kyung‐Ho organization: Hallym University Sacred Heart Hospital – sequence: 21 givenname: Mi Sun surname: Oh fullname: Oh, Mi Sun organization: Hallym University Sacred Heart Hospital – sequence: 22 givenname: Dong‐Eog surname: Kim fullname: Kim, Dong‐Eog organization: Dongguk University Ilsan Hospital – sequence: 23 givenname: Jay Chol surname: Choi fullname: Choi, Jay Chol organization: Jeju National University Hospital, Jeju National University School of Medicine – sequence: 24 givenname: Jee‐Hyun surname: Kwon fullname: Kwon, Jee‐Hyun organization: Ulsan University College of Medicine – sequence: 25 givenname: Wook‐Joo surname: Kim fullname: Kim, Wook‐Joo organization: Ulsan University College of Medicine – sequence: 26 givenname: Dong‐Ick surname: Shin fullname: Shin, Dong‐Ick organization: Chungbuk National University Hospital – sequence: 27 givenname: Kyu Sun surname: Yum fullname: Yum, Kyu Sun organization: Chungbuk National University Hospital – sequence: 28 givenname: Sung Il surname: Sohn fullname: Sohn, Sung Il organization: Keimyung University Dongsan Medical Center – sequence: 29 givenname: Jeong‐Ho surname: Hong fullname: Hong, Jeong‐Ho organization: Keimyung University Dongsan Medical Center – sequence: 30 givenname: Sang‐Hwa orcidid: 0000-0002-0609-1551 surname: Lee fullname: Lee, Sang‐Hwa organization: Hallym University Chuncheon Sacred Heart Hospital – sequence: 31 givenname: Chulho surname: Kim fullname: Kim, Chulho organization: Hallym University Chuncheon Sacred Heart Hospital – sequence: 32 givenname: Man‐Seok surname: Park fullname: Park, Man‐Seok organization: Chonnam National University Hospital, Chonnam National University Medical School – sequence: 33 givenname: Wi‐Sun orcidid: 0000-0002-2823-5253 surname: Ryu fullname: Ryu, Wi‐Sun organization: Artificial Intelligence Research Center, JLK Inc – sequence: 34 givenname: Kwang‐Yeol surname: Park fullname: Park, Kwang‐Yeol organization: Chung‐Ang University College of Medicine, Chung‐Ang University Hospital – sequence: 35 givenname: Juneyoung surname: Lee fullname: Lee, Juneyoung organization: Korea University College of Medicine – sequence: 36 givenname: Jeffrey L. surname: Saver fullname: Saver, Jeffrey L. organization: University of California – sequence: 37 givenname: Hee‐Joon orcidid: 0000-0003-0051-1997 surname: Bae fullname: Bae, Hee‐Joon email: braindoc@snu.ac.kr organization: Seoul National University College of Medicine, Seoul National University Bundang Hospital |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39714194$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kV9vFCEUxYmpsX_0wS9gSHzRh2lhYGaYJ9M0qzZp9EWfCTCXXeoMrAPTZr-9t921URNJCDfwuyfnck7JUUwRCHnN2TnHdQERzjvGmHxGTrhsVcWF4EdYi4ZXDWf8mJzmfItE3dXsBTkWfccl7-UJubuOflwgOqDJ0-0MuczpB9D1uHMwBUdzMWXJNEWaluLSBJnaHTVroCHSrSkBYsn0PpQNNW4peJ3d5tD5qGTiQIdgLBRsnWAcA-q9JM-9GTO8Opxn5PvH1berz9XN10_XV5c3lZNMysrC0EvGTc3ZoGxtLQPvBtsZ64xlombN0KneKuOtl0p44drWetc3uGtlvTgjH_a628VOMDg0O5tRb-cwmXmnkwn675cYNnqd7jTnbSu7WqHCu4PCnH4u-D16wglxDBMhLVkLLlXDWKskom__QW_TMkecD6kGjXZ19yD45k9LT15-Z4LA-z3g5pTzDP4J4Uw_5K0xb_2YN7IXe_Y-jLD7P6hXX1b7jl9Xzq7Z |
| Cites_doi | 10.5853/jos.2014.16.3.161 10.1161/STROKEAHA.113.001318 10.1161/STROKEAHA.111.621649 10.7326/M16-2607 10.1161/JAHA.116.005446 10.1097/01.EDE.0000042804.12056.6C 10.1111/ijs.12199 10.1016/j.wneu.2020.01.042 10.1186/s12933-019-0909-y 10.3389/fendo.2021.571568 10.2337/dc22-S013 10.14336/AD.2014.0330 10.1161/01.STR.24.1.35 10.2337/dc11-s216 10.1161/JAHA.122.027684 10.1001/jama.2019.9346 10.1212/WNL.0000000000012729 10.1016/j.diabres.2023.110257 10.1161/STR.0000000000000375 10.1001/archinte.163.15.1825 10.2337/dc19-0442 10.5853/jos.2015.17.1.38 10.1056/NEJMoa0802743 10.1016/j.jstrokecerebrovasdis.2018.10.026 10.1177/23969873221100032 10.1016/S1474-4422(12)70005-4 10.2337/dc22-S002 10.2337/dci18-0052 10.2337/ds18-0033 |
| ContentType | Journal Article |
| Copyright | 2024 The Author(s). published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. 2024 The Author(s). European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. 2024. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2024 The Author(s). published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. – notice: 2024 The Author(s). European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. – notice: 2024. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | 24P AAYXX CITATION CGR CUY CVF ECM EIF NPM 7TK 7U7 C1K K9. 7X8 5PM |
| DOI | 10.1111/ene.70004 |
| DatabaseName | Wiley Online Library Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Neurosciences Abstracts Toxicology Abstracts Environmental Sciences and Pollution Management ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Toxicology Abstracts Neurosciences Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | ProQuest Health & Medical Complete (Alumni) MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitleAlternate | HbA1c and age in patients with acute ischemic stroke and diabetes mellitus |
| EISSN | 1468-1331 |
| EndPage | n/a |
| ExternalDocumentID | PMC11664728 39714194 10_1111_ene_70004 ENE70004 |
| Genre | researchArticle Multicenter Study Journal Article |
| GrantInformation_xml | – fundername: the Korea National Institute of Health (KNIH) research project funderid: 2023‐ER‐1006‐01 – fundername: the Chonnam National University Hospital Biomedical Research Institute funderid: BCRI24042 – fundername: the Korea National Institute of Health (KNIH) research project grantid: 2023-ER-1006-01 – fundername: the Chonnam National University Hospital Biomedical Research Institute grantid: BCRI24042 |
| GroupedDBID | --- .3N .GA .Y3 05W 0R~ 10A 169 1OB 1OC 24P 29G 31~ 33P 36B 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5VS 66C 702 7PT 7X7 8-0 8-1 8-3 8-4 8-5 8FI 8FJ 8UM 930 A01 A03 AAESR AAEVG AAHHS AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABEML ABIVO ABJNI ABPVW ABUWG ABXGK ACAHQ ACBWZ ACCFJ ACCMX ACCZN ACGFS ACGOF ACMXC ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADPDF ADXAS ADZMN ADZOD AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFEBI AFGKR AFKRA AFPWT AFRAH AFWVQ AFZJQ AHMBA AIACR AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BENPR BFHJK BHBCM BMXJE BROTX BRXPI BY8 C45 CAG CCPQU COF CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DU5 EBS EJD EMOBN ESX EX3 F00 F5P FEDTE FUBAC FYBCS FYUFA G-S G.N GODZA H.X HF~ HMCUK HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OVD OVEED P2P P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 R.K RIG RIWAO RJQFR ROL RPM RX1 SAMSI SUPJJ TEORI UB1 UKHRP W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WVDHM WXI WXSBR XG1 YFH ZZTAW ~IA ~WT AAYXX AGQPQ CITATION CGR CUY CVF ECM EIF NPM 7TK 7U7 AAMMB AEFGJ AGXDD AIDQK AIDYY C1K K9. WIN 7X8 GROUPED_DOAJ PHGZM 5PM |
| ID | FETCH-LOGICAL-c4044-bed9401a210d8b2bb0efcdb7abcab03205d789b8afbf483f3c66bfc95fc928bf3 |
| IEDL.DBID | 24P |
| ISSN | 1351-5101 1468-1331 |
| IngestDate | Thu Aug 21 18:30:14 EDT 2025 Sun Sep 28 11:02:21 EDT 2025 Wed Aug 13 10:32:07 EDT 2025 Wed Feb 19 01:59:10 EST 2025 Tue Jul 01 03:16:04 EDT 2025 Wed Jan 22 09:30:26 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | glycated hemoglobin (hbA1c) prestroke glycemic status diabetes acute ischemic stroke age |
| Language | English |
| License | Attribution-NonCommercial-NoDerivs 2024 The Author(s). European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c4044-bed9401a210d8b2bb0efcdb7abcab03205d789b8afbf483f3c66bfc95fc928bf3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-8120-2469 0000-0002-2719-3012 0000-0003-0051-1997 0000-0002-0609-1551 0000-0002-2823-5253 0000-0003-4028-8339 |
| OpenAccessLink | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fene.70004 |
| PMID | 39714194 |
| PQID | 3157897278 |
| PQPubID | 1066358 |
| PageCount | 11 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_11664728 proquest_miscellaneous_3148500684 proquest_journals_3157897278 pubmed_primary_39714194 crossref_primary_10_1111_ene_70004 wiley_primary_10_1111_ene_70004_ENE70004 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | January 2025 |
| PublicationDateYYYYMMDD | 2025-01-01 |
| PublicationDate_xml | – month: 01 year: 2025 text: January 2025 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: Oxford – name: Hoboken |
| PublicationTitle | European journal of neurology |
| PublicationTitleAlternate | Eur J Neurol |
| PublicationYear | 2025 |
| Publisher | John Wiley & Sons, Inc John Wiley and Sons Inc |
| Publisher_xml | – name: John Wiley & Sons, Inc – name: John Wiley and Sons Inc |
| References | 2017; 6 1993; 24 2015; 17 2015; 6 2023; 12 2013; 44 2022; 45 2003; 14 2019; 322 2019; 18 2018; 41 2011; 34 2021; 52 2012; 11 2021; 97 2021; 12 2019; 42 2023; 196 2022; 7 2011; 42 2019; 28 2014; 16 2008; 358 2020; 136 2014; 9 2017; 167 2018; 31 2003; 163 e_1_2_12_4_1 e_1_2_12_3_1 e_1_2_12_6_1 e_1_2_12_5_1 e_1_2_12_19_1 e_1_2_12_18_1 e_1_2_12_2_1 e_1_2_12_17_1 e_1_2_12_16_1 e_1_2_12_20_1 e_1_2_12_21_1 e_1_2_12_22_1 e_1_2_12_23_1 e_1_2_12_24_1 e_1_2_12_25_1 e_1_2_12_26_1 e_1_2_12_27_1 e_1_2_12_28_1 e_1_2_12_29_1 e_1_2_12_30_1 e_1_2_12_15_1 e_1_2_12_14_1 e_1_2_12_13_1 e_1_2_12_12_1 e_1_2_12_8_1 e_1_2_12_11_1 e_1_2_12_7_1 e_1_2_12_10_1 e_1_2_12_9_1 |
| References_xml | – volume: 14 start-page: 300 year: 2003 end-page: 306 article-title: Quantifying biases in causal models: classical confounding vs collider‐stratification bias publication-title: Epidemiology – volume: 9 start-page: 514 year: 2014 end-page: 518 article-title: Current status of acute stroke management in Korea: a report on a multicenter, comprehensive acute stroke registry publication-title: Int J Stroke – volume: 322 start-page: 326 year: 2019 end-page: 335 article-title: Intensive vs standard treatment of hyperglycemia and functional outcome in patients with acute ischemic stroke: the SHINE randomized clinical trial publication-title: JAMA – volume: 34 start-page: S184 issue: Suppl 2 year: 2011 end-page: S190 article-title: The pros and cons of diagnosing diabetes with A1C publication-title: Diabetes Care – volume: 12 year: 2021 article-title: Meta‐analysis: association between hypoglycemia and serious adverse events in older patients treated with glucose‐lowering agents publication-title: Front Endocrinol (Lausanne) – volume: 97 start-page: e1717 year: 2021 end-page: e1726 article-title: Association of Prestroke Glycemic Control with Vascular Events during 1‐year follow‐up publication-title: Neurology – volume: 28 start-page: 470 year: 2019 end-page: 476 article-title: Impact of elevated hemoglobin A1c levels on functional outcome in patients with acute ischemic stroke publication-title: J Stroke Cerebrovasc Dis – volume: 41 start-page: 2648 year: 2018 end-page: 2668 article-title: Evaluation and Management of Youth‐Onset Type 2 diabetes: a position statement by the American Diabetes Association publication-title: Diabetes Care – volume: 45 start-page: S195 year: 2022 end-page: S207 article-title: 13. Older adults: standards of medical Care in Diabetes‐2022 publication-title: Diabetes Care – volume: 6 start-page: 156 year: 2015 end-page: 167 article-title: Hypoglycemia in older people—a less well recognized risk factor for frailty publication-title: Aging Dis – volume: 45 start-page: S17 year: 2022 end-page: S38 article-title: 2. Classification and diagnosis of diabetes: standards of medical Care in Diabetes‐2022 publication-title: Diabetes Care – volume: 24 start-page: 35 year: 1993 end-page: 41 article-title: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of org 10172 in acute stroke treatment publication-title: Stroke – volume: 358 start-page: 2545 year: 2008 end-page: 2559 article-title: Effects of intensive glucose lowering in type 2 diabetes publication-title: N Engl J Med – volume: 52 start-page: e364 year: 2021 end-page: e467 article-title: 2021 guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association publication-title: Stroke – volume: 31 start-page: 245 year: 2018 end-page: 253 article-title: Diabetes Management in the Elderly publication-title: Diabetes Spectr – volume: 16 start-page: 161 year: 2014 end-page: 172 article-title: MRI‐based algorithm for acute ischemic stroke subtype classification publication-title: J Stroke – volume: 136 start-page: e487 year: 2020 end-page: e495 article-title: Intensive versus standard glucose control in patients with ischemic stroke: a meta‐analysis of randomized controlled trials publication-title: World Neurosurg – volume: 11 start-page: 261 year: 2012 end-page: 271 article-title: Diabetes, hyperglycaemia, and acute ischaemic stroke publication-title: Lancet Neurol – volume: 44 start-page: 1500 year: 2013 end-page: 1504 article-title: Diabetes mellitus: a risk factor for ischemic stroke in a large biracial population publication-title: Stroke – volume: 167 start-page: 268 year: 2017 end-page: 274 article-title: Sensitivity analysis in observational research: introducing the E‐value publication-title: Ann Intern Med – volume: 163 start-page: 1825 year: 2003 end-page: 1829 article-title: Hypoglycemia as a predictor of mortality in hospitalized elderly patients publication-title: Arch Intern Med – volume: 17 start-page: 38 year: 2015 end-page: 53 article-title: Case characteristics, hyperacute treatment, and outcome information from the clinical research center for stroke‐fifth division registry in South Korea publication-title: J Stroke – volume: 12 year: 2023 article-title: Age‐dependent association between modifiable risk factors and incident cardiovascular disease publication-title: J Am Heart Assoc – volume: 42 start-page: 1966 year: 2019 end-page: 1972 article-title: Does the Association of Diabetes with Stroke Risk Differ by age, race, and sex? Results from the REasons for geographic and racial differences in stroke (REGARDS) study publication-title: Diabetes Care – volume: 196 year: 2023 article-title: Admission hyperglycemia, stroke subtypes, outcomes in acute ischemic stroke publication-title: Diabetes Res Clin Pract – volume: 18 start-page: 103 year: 2019 article-title: Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population‐based cohort study publication-title: Cardiovasc Diabetol – volume: 42 start-page: 2758 year: 2011 end-page: 2762 article-title: Diabetes and poor outcomes within 6 months after acute ischemic stroke: the China National Stroke Registry publication-title: Stroke – volume: 7 start-page: I‐II year: 2022 article-title: European stroke organisation (ESO) guideline on pharmacological interventions for long‐term secondary prevention after ischaemic stroke or transient ischaemic attack publication-title: Eur Stroke J – volume: 6 year: 2017 article-title: Recurrent stroke in minor ischemic stroke or transient ischemic attack with metabolic syndrome and/or diabetes mellitus publication-title: J Am Heart Assoc – ident: e_1_2_12_18_1 doi: 10.5853/jos.2014.16.3.161 – ident: e_1_2_12_22_1 doi: 10.1161/STROKEAHA.113.001318 – ident: e_1_2_12_3_1 doi: 10.1161/STROKEAHA.111.621649 – ident: e_1_2_12_19_1 doi: 10.7326/M16-2607 – ident: e_1_2_12_2_1 doi: 10.1161/JAHA.116.005446 – ident: e_1_2_12_30_1 doi: 10.1097/01.EDE.0000042804.12056.6C – ident: e_1_2_12_14_1 doi: 10.1111/ijs.12199 – ident: e_1_2_12_7_1 doi: 10.1016/j.wneu.2020.01.042 – ident: e_1_2_12_28_1 doi: 10.1186/s12933-019-0909-y – ident: e_1_2_12_25_1 doi: 10.3389/fendo.2021.571568 – ident: e_1_2_12_10_1 doi: 10.2337/dc22-S013 – ident: e_1_2_12_26_1 doi: 10.14336/AD.2014.0330 – ident: e_1_2_12_17_1 doi: 10.1161/01.STR.24.1.35 – ident: e_1_2_12_23_1 doi: 10.2337/dc11-s216 – ident: e_1_2_12_13_1 doi: 10.1161/JAHA.122.027684 – ident: e_1_2_12_6_1 doi: 10.1001/jama.2019.9346 – ident: e_1_2_12_5_1 doi: 10.1212/WNL.0000000000012729 – ident: e_1_2_12_21_1 doi: 10.1016/j.diabres.2023.110257 – ident: e_1_2_12_8_1 doi: 10.1161/STR.0000000000000375 – ident: e_1_2_12_27_1 doi: 10.1001/archinte.163.15.1825 – ident: e_1_2_12_12_1 doi: 10.2337/dc19-0442 – ident: e_1_2_12_15_1 doi: 10.5853/jos.2015.17.1.38 – ident: e_1_2_12_29_1 doi: 10.1056/NEJMoa0802743 – ident: e_1_2_12_4_1 doi: 10.1016/j.jstrokecerebrovasdis.2018.10.026 – ident: e_1_2_12_9_1 doi: 10.1177/23969873221100032 – ident: e_1_2_12_20_1 doi: 10.1016/S1474-4422(12)70005-4 – ident: e_1_2_12_16_1 doi: 10.2337/dc22-S002 – ident: e_1_2_12_24_1 doi: 10.2337/dci18-0052 – ident: e_1_2_12_11_1 doi: 10.2337/ds18-0033 |
| SSID | ssj0002720 |
| Score | 2.447921 |
| Snippet | Background
This study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients... This study aimed to explore the association between admission HbA1c and the risk of 1-year vascular outcomes stratified by age group in patients with acute... BackgroundThis study aimed to explore the association between admission HbA1c and the risk of 1‐year vascular outcomes stratified by age group in patients with... |
| SourceID | pubmedcentral proquest pubmed crossref wiley |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | e70004 |
| SubjectTerms | acute ischemic stroke Age Age Factors Age groups Aged Aged, 80 and over Blood Glucose - metabolism Diabetes Diabetes mellitus Diabetes Mellitus - blood Diabetes Mellitus - epidemiology Female glycated hemoglobin (hbA1c) Glycated Hemoglobin - analysis Glycated Hemoglobin - metabolism Heterogeneity Humans Ischemia Ischemic Stroke - blood Ischemic Stroke - epidemiology Male Middle Aged Original prestroke glycemic status Prospective Studies Risk Statistical models Stroke |
| Title | Influence of prestroke glycemic status on outcomes by age in patients with acute ischemic stroke and diabetes mellitus |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fene.70004 https://www.ncbi.nlm.nih.gov/pubmed/39714194 https://www.proquest.com/docview/3157897278 https://www.proquest.com/docview/3148500684 https://pubmed.ncbi.nlm.nih.gov/PMC11664728 |
| Volume | 32 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3dS8MwEA9DQXwRv50fI4oPvlTWNmlTfFKZTGFjiMLeStKkOtRWbCv433uXtcUhgg8tpUnTNr_kcndJfkfIqUqTgPsycKRKtMO0ZI4yOF1ohAajBcZEG2NpNA6Gj-xuyqcdctHshZnzQ7QON-wZVl5jB5eq-NHJQRSch33LBboMSr2Pzdtjk1YM4wSjtba462DDq2mFcBlP--jiYPRLw_y9UPKnAmtHoJt1slarjvRyjvUG6Zhsk6yM6snxLfJ52wQcoXlKcYFr-ZG_GPr0-pXgEniKm4eqguYZzasSftcUVH1RECh0ltGaYLWg6JmlMqlKuA2mb_2kLUlmmjbOWvqGVJ5Q3jZ5vBk8XA-dOqyCk7A-Qyx0BFaVBGNPC-Up1TdpolUIaEmF8dS5DkWkhExVyoSf-kkQAKQRh8MTKvV3yFKWZ2aPUC40M2COSwWjHNe-gKrSnCNtmgxDobvkpKnf-H3OnhE3VgeAEFsQuuSwqfm47kBF7LsgSiJQrkSXHLfJ0PRxPkNmJq8wDxMc97hAEbtzoNq3gJrlMjeCFLEAYZsBabUXU7LZs6XXdt0AOfXhxWcW7b-_PB6MB_Zi__9ZD8iqhyGErRfnkCyVH5U5Ar2mVD3bfuEcTsMeWb4ajCf3PesjwPO917OuqG8zh_y1 |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwEB6tQGq5AG15LCytW_XQS1abjZ04Ui8VWrS07B4qkLhUkR07gGiTik0qwa9nxnnAFlVCPUSKYsd24hl7Xv4G4KPO0lAEKvSUTo3HjeKetuQutNKg0oJ7osuxNJuH0zP-9Vyc9-BzexamxofoDG7EGW69JgYng_QjLse1YBiNHBjoqvPPkUj0_QE8ijyMTt0SvkeU1-AKURxP9-rybvRExHwaKflYgnVb0NEG_GgHX0eeXA-rUg_Tu79wHf_36zZhvZFN2ZeamF5Bz-av4cWs8b6_gT_HbUYTVmSMImjLm-LasouftynF2DM6nVQtWJGzoiqxR7tg-pbhisWuctYguC4YmX6ZSqsSH6Nu3bzpWlK5Ya01mP0irFBsbwvOjianh1OvydvgpXzEabJNjGqbQm3SSD3WemSz1OgIyUFpStguTCRjLVWmMy6DLEjDEGkmFniNpc6CbVjJi9zuAhPScIv6vtK4jQoTSJwKIwThsqkokqYPH9r5S37X8BxJq9bgH0zcH-zDoJ3ZpOHQRRL4uFbFKL3JPrzvipG3yGGicltUVIdLQYdosImdmhC6XlCO87kfY4lcIpGuAuF2L5fkV5cOv9v3QwLtx44_ORL498iTyXzibvaeX_UdvJyezk6Sk-P5t31YG1O-YmcyGsBKeVPZAxSiSv3W8co9xMkbbA |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3NS8MwFA9DQbyI306nRvHgpbKuSZviSXRjfmzsoOCtJE2qQ22HawX_e9_L2uIYgodCadKkze8l7718_B4hZyqJfe5J35Eq1g7TkjnK4HKhERqcFtCJNsbSYOj3n9jdM39ukMvqLMyMH6KecMOeYcdr7OATnfzq5DAUXARtywW6zEDuULw7bFQPw7jAaL0t7jooeCWtEG7jqV-dV0YLFubiRsnfBqzVQL11slaajvRqhvUGaZh0k6wMysXxLfJ1WwUcoVlCcYNr_pm9Gfry_h3jFniKh4eKKc1SmhU5_K6ZUvVNYUCh45SWBKtTijOzVMZFDo_B9S3ftCXJVNNqspZ-IJUnlLdNnnrdx-u-U4ZVcGLWZoiFDsGrkuDsaaE6SrVNEmsVAFpSYTx1rgMRKiETlTDhJV7s-wBpyOHqCJV4O2QpzVKzRygXmhlwx6UCLce1J6CpNOdImyaDQOgmOa3aN5rM2DOiyusAECILQpO0qpaPyg40jTwXIA3BuBJNclIng-jjeoZMTVZgHiY4nnGBInZnQNW1gJnlMjeEFDEHYZ0BabXnU9Lxq6XXdl0fOfWh4nOL9t9fHnWHXXuz__-sx2RldNOLHm6H9wdktYPRhO2EToss5Z-FOQQTJ1dHVpR_AOXd-ec |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Influence+of+prestroke+glycemic+status+on+outcomes+by+age+in+patients+with+acute+ischemic+stroke+and+diabetes+mellitus&rft.jtitle=European+journal+of+neurology&rft.au=Kim%2C+Joon%E2%80%90Tae&rft.au=Lee%2C+Ji+Sung&rft.au=Kim%2C+Hyunsoo&rft.au=Kim%2C+Beom+Joon&rft.date=2025-01-01&rft.issn=1351-5101&rft.eissn=1468-1331&rft.volume=32&rft.issue=1&rft.epage=n%2Fa&rft_id=info:doi/10.1111%2Fene.70004&rft.externalDBID=10.1111%252Fene.70004&rft.externalDocID=ENE70004 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1351-5101&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1351-5101&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1351-5101&client=summon |