Advancing Ki67 hotspot detection in breast cancer: a comparative analysis of automated digital image analysis algorithms - Zwager, Mieke C; Yu, Shibo; Buikema, Henk J; Bock, Geertruida H; Ramsing, Thomas W; Thagaard, Jeppe; Koopman, Timco; Vegt, Bert (Histopathology, 2025)
Keywords: Algorithms; artificial intelligence (AI); Automation; Biomarkers, Tumor - analysis; breast cancer; Breast carcinoma; Breast Neoplasms - diagnosis; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Comparative analysis; Deep Learning; digital image analysis (DIA); Female; hotspot; Humans; Image processing; Image Processing, Computer-Assisted - methods; Immunohistochemistry - methods; Ki-67 Antigen - analysis; Ki-67 Antigen - metabolism; Ki67 proliferation index; Original; Research hot spots; Ki67 proliferation index; breast cancer; hotspot; artificial intelligence (AI); digital image analysis (DIA)