Associations between life's essential 8 and femoral neck bone mineral density among adults: A national population-based study
Osteoporosis represents a significant public health issue, impacting both health outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from the National Health and Nutrition Examination Surve...
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| Published in | Medicine (Baltimore) Vol. 103; no. 36; p. e39540 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Hagerstown, MD
Lippincott Williams & Wilkins
06.09.2024
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0025-7974 1536-5964 1536-5964 |
| DOI | 10.1097/MD.0000000000039540 |
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| Abstract | Osteoporosis represents a significant public health issue, impacting both health outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from the National Health and Nutrition Examination Survey (NHANES) spanning 2011 to 2018 were analyzed in this cross-sectional analysis, including 9018 subjects following the exclusion of individuals lacking BMD or LE8 data. The LE8 score, comprising factors such as diet, physical activity, smoking status, sleep quality, body mass index, lipid profiles, blood glucose, and blood pressure, was used to evaluate cardiovascular health. BMD was determined through dual-energy X-ray absorptiometry (DXA). Relationships between the LE8 scores and BMD at the femoral neck were assessed using linear regression and smooth curve fitting techniques. Enhanced LE8 scores were linked to improved BMD at the femoral neck. Notably, a 10-point increment in the LE8 score was associated with a rise in BMD by 0.04 g/cm² [β = 0.04, 95% CI: 0.03-0.05]. The data indicate a strong positive association between cardiovascular health, as measured by LE8, and BMD. These results support the development of holistic health strategies that promote cardiovascular health to potentially improve bone density. |
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| AbstractList | Osteoporosis represents a significant public health issue, impacting both health outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from the National Health and Nutrition Examination Survey (NHANES) spanning 2011 to 2018 were analyzed in this cross-sectional analysis, including 9018 subjects following the exclusion of individuals lacking BMD or LE8 data. The LE8 score, comprising factors such as diet, physical activity, smoking status, sleep quality, body mass index, lipid profiles, blood glucose, and blood pressure, was used to evaluate cardiovascular health. BMD was determined through dual-energy X-ray absorptiometry (DXA). Relationships between the LE8 scores and BMD at the femoral neck were assessed using linear regression and smooth curve fitting techniques. Enhanced LE8 scores were linked to improved BMD at the femoral neck. Notably, a 10-point increment in the LE8 score was associated with a rise in BMD by 0.04 g/cm² [β = 0.04, 95% CI: 0.03-0.05]. The data indicate a strong positive association between cardiovascular health, as measured by LE8, and BMD. These results support the development of holistic health strategies that promote cardiovascular health to potentially improve bone density. Osteoporosis represents a significant public health issue, impacting both health outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from the National Health and Nutrition Examination Survey (NHANES) spanning 2011 to 2018 were analyzed in this cross-sectional analysis, including 9018 subjects following the exclusion of individuals lacking BMD or LE8 data. The LE8 score, comprising factors such as diet, physical activity, smoking status, sleep quality, body mass index, lipid profiles, blood glucose, and blood pressure, was used to evaluate cardiovascular health. BMD was determined through dual-energy X-ray absorptiometry (DXA). Relationships between the LE8 scores and BMD at the femoral neck were assessed using linear regression and smooth curve fitting techniques. Enhanced LE8 scores were linked to improved BMD at the femoral neck. Notably, a 10-point increment in the LE8 score was associated with a rise in BMD by 0.04 g/cm² [β = 0.04, 95% CI: 0.03-0.05]. The data indicate a strong positive association between cardiovascular health, as measured by LE8, and BMD. These results support the development of holistic health strategies that promote cardiovascular health to potentially improve bone density.Osteoporosis represents a significant public health issue, impacting both health outcomes and economic costs. This research investigates how cardiovascular health, as indicated by the LE8 score, correlates with bone mineral density (BMD). Data from the National Health and Nutrition Examination Survey (NHANES) spanning 2011 to 2018 were analyzed in this cross-sectional analysis, including 9018 subjects following the exclusion of individuals lacking BMD or LE8 data. The LE8 score, comprising factors such as diet, physical activity, smoking status, sleep quality, body mass index, lipid profiles, blood glucose, and blood pressure, was used to evaluate cardiovascular health. BMD was determined through dual-energy X-ray absorptiometry (DXA). Relationships between the LE8 scores and BMD at the femoral neck were assessed using linear regression and smooth curve fitting techniques. Enhanced LE8 scores were linked to improved BMD at the femoral neck. Notably, a 10-point increment in the LE8 score was associated with a rise in BMD by 0.04 g/cm² [β = 0.04, 95% CI: 0.03-0.05]. The data indicate a strong positive association between cardiovascular health, as measured by LE8, and BMD. These results support the development of holistic health strategies that promote cardiovascular health to potentially improve bone density. |
| Author | Xiao, Xiangjun Zhang, An Liu, Linjian |
| Author_xml | – sequence: 1 givenname: Linjian surname: Liu fullname: Liu, Linjian email: LLJ19807340073@Outlook.com organization: Hengyang Medical School, University of South China, Hengyang, China – sequence: 2 givenname: An surname: Zhang fullname: Zhang, An email: 561466114@qq.com organization: Department of Pharmacy, The Xiangxi Autonomous Prefecture Traditional Chinese Medicine Hospital, Jishou, China – sequence: 3 givenname: Xiangjun surname: Xiao fullname: Xiao, Xiangjun email: 3670007@qq.com organization: Hengyang Medical School, University of South China, Hengyang, China |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39252265$$D View this record in MEDLINE/PubMed |
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| Issue | 36 |
| Keywords | bone mineral density life's essential 8 National Health and Nutrition Examination Survey osteoporosis cardiovascular health |
| Language | English |
| License | http://creativecommons.org/licenses/by/4.0 Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| Notes | Received: 8 June 2024 / Received in final form: 16 July 2024 / Accepted: 12 August 2024 This study were funded by Hunan Clinical Research Center of Wound Repair and Functional Reconstruction for Hand and Foot (No. 2021SK4030) and National Key Clinical Specialty Major Scientific Research Project (No. Z2023083). This study's segments involving human subjects, materials, or data complied with the Declaration of Helsinki standards and received approval from the NCHS Ethics Review Board. Written consent was obtained from all patients/participants. The authors affirm that there are no financial conflicts of interest to disclose. The datasets generated during and/or analyzed during the current study are publicly available. Supplemental Digital Content is available for this article. How to cite this article: Liu L, Zhang A, Xiao X. Associations between life's essential 8 and femoral neck bone mineral density among adults: A national population-based study. Medicine 2024;103:36(e39540). *Correspondence: Xiangjun Xiao, Department of Hand and foot surgery, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang 421002, China (e-mail: 3670007@qq.com). ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
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| SubjectTerms | Absorptiometry, Photon Adult Aged Blood Glucose - analysis Blood Pressure - physiology Body Mass Index Bone Density - physiology Cross-Sectional Studies Diet Exercise - physiology Female Femur Neck - diagnostic imaging Humans Male Middle Aged Nutrition Surveys Observational Study Osteoporosis - epidemiology |
| Title | Associations between life's essential 8 and femoral neck bone mineral density among adults: A national population-based study |
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