Cohort differences between preschool development of in vitro fertilization and naturally conceived infants

• Published in: Medicine (Baltimore) Vol. 103; no. 27; p. e38190
• Main Authors: Guo, Chunyan, Wang, Jingcai, Yang, Lixin, Wu, Yanqiu, Liu, Xia, Zhou, Qili
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 05.07.2024
• Subjects: Child Development - physiology; Child, Preschool; Cohort Studies; Educational Status; Female; Fertilization in Vitro - methods; Fertilization in Vitro - statistics & numerical data; Humans; Male; Observational Study; in vitro fertilization; preschool age; assisted reproductive technology; naturally conceived children; psychomotor development
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000038190

To explore the differential cohort situation between preschool development of in vitro fertilization (IVF) and naturally conceived infants. From April 2014 to June 2022, 60 preschool IVFs were selected as the research subjects for follow-up at the pediatric health clinic of hospital's prevention and health department. They were set as the experimental group (Group S), and 60 naturally conceived infants of the same age were selected as the control group (Group Z). Data from both groups were collected through telephone follow-up and other methods. No significant difference showed between the 2 groups in age specific height, age specific weight, Gesell developmental score, Denver developmental screening test screening results, intellectual development index, and motor development index (P > .05). The influence of birth environment factors such as family background and maternal education level on children's height and weight was not significant (P > .05), while maternal education level had a significant impact on children's intellectual development index (P < .05). No significant difference showed in the development of preschool children in IVF compared to naturally conceived children, and the level of parental education has a significant impact on children's mental and motor development.