Effect of glycemic gap on short term outcome in critically ill patient: In zagazig university hospitals

• Published in: Diabetes & metabolic syndrome clinical research & reviews Vol. 13; no. 2; pp. 1325 - 1328
• Main Authors: Fawzy, Farid, Saad, Mohamed S.S., ElShabrawy, Arafa M., Eltohamy, Maisoon M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.03.2019
• Subjects: APACHE; Biomarkers - analysis; Blood Glucose - analysis; Critical Illness - mortality; Critically ill patients; Cross-Sectional Studies; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Female; Follow-Up Studies; Glycated Hemoglobin A - analysis; Glycemic gap; Humans; Hyperglycemia - etiology; Hyperglycemia - mortality; Hyperglycemia - pathology; Intensive Care Units - statistics & numerical data; Male; Middle Aged; Outcome; Outcome Assessment, Health Care; Prognosis; ROC Curve; Severity of Illness Index; Survival Rate; Glycemic gap; Outcome; Critically ill patients
• ISSN: 1871-4021; 1878-0334; 1878-0334
• DOI: 10.1016/j.dsx.2019.01.042

Both admission Blood glucose and previous glycemic state may affect critically ill patients; So Glycemic gap may be a good indicator of ICU outcomes. This study investigated the effect of glycemic gap on short term outcome in critically ill patient and the value of incorporation of the Glycemic Gap into the APACHE-II on its discriminative performance. This cross sectional study was conducted in medical ICU of Zagazig University Hospitals, March 2018 to September 2018; total numbers of 240 critically ill patients admitted to ICU were enrolled in. All of them were subjected to: full history taking, clinical examination, routine investigations, random blood sugar, hemoglobin A1c. ADAG, Glycemic Gap and APACHE II were calculated. Elevated glycemic gap was associated with an increased ICU mortality and APACHE-II score was a good predictor of ICU mortality in critically ill patients. Elevated glycemic gap was significantly associated with an increased ICU mortality that the glycemic gap can be used to assess the severity and prognosis of critically ill patients and their incorporation into the APACHE II score has increased its performance as a predictor of mortality.