Case report: hibernoma, a rare male breast mass
Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females...
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Published in | Journal of surgical case reports Vol. 2025; no. 1; p. rjae820 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Oxford University Press
01.01.2025
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Subjects | |
Online Access | Get full text |
ISSN | 2042-8812 2042-8812 |
DOI | 10.1093/jscr/rjae820 |
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Abstract | Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females than males. This case report highlights a unique presentation of a 20 cm hibernoma mass found in the right breast of a 31-year-old male. A diagnostic bilateral mammogram, unilateral MRI, and ultrasound were used to evaluate the mass. The patient underwent an intra-operative ultrasound-guided needle biopsy and left total mastectomy, revealing the diagnosis of hibernoma with fat necrosis. This report aims to delineate the pathological, diagnostic, and clinical features associated with breast hibernomas and to offer a comprehensive review of the literature on the subject. This case report also serves to expand the differential for breast mass in male patients, with a focused aim to prevent delayed diagnosis and treatment. |
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AbstractList | Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females than males. This case report highlights a unique presentation of a 20 cm hibernoma mass found in the right breast of a 31-year-old male. A diagnostic bilateral mammogram, unilateral MRI, and ultrasound were used to evaluate the mass. The patient underwent an intra-operative ultrasound-guided needle biopsy and left total mastectomy, revealing the diagnosis of hibernoma with fat necrosis. This report aims to delineate the pathological, diagnostic, and clinical features associated with breast hibernomas and to offer a comprehensive review of the literature on the subject. This case report also serves to expand the differential for breast mass in male patients, with a focused aim to prevent delayed diagnosis and treatment.Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females than males. This case report highlights a unique presentation of a 20 cm hibernoma mass found in the right breast of a 31-year-old male. A diagnostic bilateral mammogram, unilateral MRI, and ultrasound were used to evaluate the mass. The patient underwent an intra-operative ultrasound-guided needle biopsy and left total mastectomy, revealing the diagnosis of hibernoma with fat necrosis. This report aims to delineate the pathological, diagnostic, and clinical features associated with breast hibernomas and to offer a comprehensive review of the literature on the subject. This case report also serves to expand the differential for breast mass in male patients, with a focused aim to prevent delayed diagnosis and treatment. Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females than males. This case report highlights a unique presentation of a 20 cm hibernoma mass found in the right breast of a 31-year-old male. A diagnostic bilateral mammogram, unilateral MRI, and ultrasound were used to evaluate the mass. The patient underwent an intra-operative ultrasound-guided needle biopsy and left total mastectomy, revealing the diagnosis of hibernoma with fat necrosis. This report aims to delineate the pathological, diagnostic, and clinical features associated with breast hibernomas and to offer a comprehensive review of the literature on the subject. This case report also serves to expand the differential for breast mass in male patients, with a focused aim to prevent delayed diagnosis and treatment. Hibernomas are rare, benign neoplasms characterized by the presence of brown adipose tissue. Although these tumors may arise in any region of brown fat, they predominantly occur in the thigh, shoulder, back, and neck. Hibernomas are rarely found in mammary tissue, with a higher prevalence in females than males. This case report highlights a unique presentation of a 20 cm hibernoma mass found in the right breast of a 31-year-old male. A diagnostic bilateral mammogram, unilateral MRI, and ultrasound were used to evaluate the mass. The patient underwent an intra-operative ultrasound-guided needle biopsy and left total mastectomy, revealing the diagnosis of hibernoma with fat necrosis. This report aims to delineate the pathological, diagnostic, and clinical features associated with breast hibernomas and to offer a comprehensive review of the literature on the subject. This case report also serves to expand the differential for breast mass in male patients, with a focused aim to prevent delayed diagnosis and treatment. |
Author | Radwan, Nawras Patel, Anjeli Yang, James Fawole, Funmilayo Christian, Derick Sajdlowska, Joanna |
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Cites_doi | 10.1093/jscr/rjad239 10.1530/JOE-18-0084 10.1097/00000478-200106000-00014 10.5152/tjbh.2015.2711 10.1093/jscr/rjad309 10.1634/theoncologist.10-7-471 10.3928/01477447-20110922-12[7] |
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Copyright | Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024. 2025 Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024. Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
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Keywords | breast mass brown fat tumor male breast mass hibernoma |
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References | Hanna (2024122616543845900_ref2) 2023; 2023 Furlong (2024122616543845900_ref5) 2001; 25 Gabra (2024122616543845900_ref1) 2023; 2023 Symonds (2024122616543845900_ref3) 2018; 238 Mavrogenis (2024122616543845900_ref4) 2011; 34 Giordano (2024122616543845900_ref7) 2005; 10 Yalaza (2024122616543845900_ref6) 2016; 12 |
References_xml | – volume: 2023 start-page: rjad239 year: 2023 ident: 2024122616543845900_ref2 article-title: Breast hibernoma in a male patient: a rare case report and review of the literature publication-title: J Surg Case Rep doi: 10.1093/jscr/rjad239 – volume: 238 start-page: R53 year: 2018 ident: 2024122616543845900_ref3 article-title: Brown adipose tissue development and function and its impact on reproduction publication-title: J Endocrinol doi: 10.1530/JOE-18-0084 – volume: 25 start-page: 809 year: 2001 ident: 2024122616543845900_ref5 article-title: The morphologic spectrum of hibernoma: a clinicopathologic study of 170 cases publication-title: Am J Surg Pathol doi: 10.1097/00000478-200106000-00014 – volume: 12 start-page: 1 year: 2016 ident: 2024122616543845900_ref6 article-title: Male breast cancer publication-title: J Breast Health doi: 10.5152/tjbh.2015.2711 – volume: 2023 start-page: rjad309 year: 2023 ident: 2024122616543845900_ref1 article-title: Lipoma-like hibernoma: a rare soft tissue tumor—a case series and review of the literature publication-title: J Surg Case Rep doi: 10.1093/jscr/rjad309 – volume: 10 start-page: 471 year: 2005 ident: 2024122616543845900_ref7 article-title: A review of the diagnosis and management of male breast cancer publication-title: Oncologist doi: 10.1634/theoncologist.10-7-471 – volume: 34 start-page: e755 year: 2011 ident: 2024122616543845900_ref4 article-title: Hibernomas: clinicopathological features, diagnosis, and treatment of 17 cases publication-title: Orthopedics doi: 10.3928/01477447-20110922-12[7] |
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Title | Case report: hibernoma, a rare male breast mass |
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