GLOBAL ASYMPTOTICAL PROPERTIES FOR A DIFFUSED HBV INFECTION MODEL WITH CTL IMMUNE RESPONSE AND NONLINEAR INCIDENCE
This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are...
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Published in | Acta mathematica scientia Vol. 31; no. 5; pp. 1959 - 1967 |
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Format | Journal Article |
Language | English |
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Elsevier Ltd
01.09.2011
College of Mathematics and Systems Science, Xinjiang University, Urumqi 830046, China Faculty of Science, Xi'an Jiaotong University, Xi'an 710049, China%College of Mathematics and Systems Science, Xinjiang University, Urumqi 830046, China%Faculty of Science, Xi'an Jiaotong University, Xi'an 710049, China |
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ISSN | 0252-9602 1572-9087 |
DOI | 10.1016/S0252-9602(11)60374-3 |
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Abstract | This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are obtained. Global stability of the positive equilibrium of the model is also considered. The results show that the free diffusion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions. |
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AbstractList | This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are obtained. Global stability of the positive equilibrium of the model is also considered. The results show that the free diffusion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions. S858.28; This article proposes a diffused hepatitis B virus (HBV) model with CTLimmune response and nonlinear incidence for the control of viral infections.By means of different Lyapunov functions,the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are obtained.Global stability of the positive equilibrium of the model is also considered.The results show that the free diffusion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions. This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are obtained. Global stability of the positive equilibrium of the model is also considered. The results show that the free diffusion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions. |
Author | 王绍利 冯新龙 何银年 |
AuthorAffiliation | Faculty of Science, Xi'an Jiaotong University;College of Mathematics and Systems Science, Xinjiang University |
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Cites_doi | 10.1016/j.jtbi.2007.11.007 10.1126/science.272.5258.74 10.1016/j.mbs.2007.05.004 10.1016/j.amc.2006.12.044 10.1007/s002850100109 10.3934/mbe.2004.1.57 10.1016/0362-546X(84)90011-7 10.7326/0003-4819-101-5-613 10.1016/S0140-6736(81)90585-7 10.1016/S0252-9602(06)60029-5 10.1016/0002-9343(94)90190-2 10.1073/pnas.93.9.4398 10.4049/jimmunol.145.10.3442 10.1128/MMBR.64.1.51-68.2000 10.1016/S1468-1218(03)00018-X 10.1016/j.jtbi.2009.01.001 10.1038/373117a0 |
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DocumentTitleAlternate | GLOBAL ASYMPTOTICAL PROPERTIES FOR A DIFFUSED HBV INFECTION MODEL WITH CTL IMMUNE RESPONSE AND NONLINEAR INCIDENCE |
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Keywords | global asymptotical stability diffusion CTL immune response 34D23 92D25 HBV infection nonlinear incidence |
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Notes | 42-1227/O This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means of different Lyapunov functions, the global asymptotical properties of the viral-free equilibrium and immune-free equilibrium of the model are obtained. Global stability of the positive equilibrium of the model is also considered. The results show that the free diffusion of the virus has no effect on the global stability of such HBV infection problem with Neumann homogeneous boundary conditions. Wang Shaoli 1 Feng Xinlong 2 He Yinnian 1,2 1. Faculty of Science, Xi’an Jiaotong University, Xi’an 710049, China 2. College of Mathematics and Systems Science, Xinjiang University, Urumqi 830046, China HBV infection; diffusion; CTL immune response; nonlinear incidence; global asymptotical stability ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
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Snippet | This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means... This article proposes a diffused hepatitis B virus (HBV) model with CTL immune response and nonlinear incidence for the control of viral infections. By means... S858.28; This article proposes a diffused hepatitis B virus (HBV) model with CTLimmune response and nonlinear incidence for the control of viral infections.By... |
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SubjectTerms | 34D23 92D25 Boundaries CTL CTL immune response diffusion global asymptotical stability HBV HBV infection Hepatitis B virus nonlinear incidence 免疫反应 平衡模型 扩散 渐近性质 病毒感染 非线性 |
Title | GLOBAL ASYMPTOTICAL PROPERTIES FOR A DIFFUSED HBV INFECTION MODEL WITH CTL IMMUNE RESPONSE AND NONLINEAR INCIDENCE |
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