SARS-CoV-2 pandemic: An overview

By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, let...

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Published inAdvances in biological regulation Vol. 77; p. 100736
Main Authors Acuti Martellucci, Cecilia, Flacco, Maria Elena, Cappadona, Rosaria, Bravi, Francesca, Mantovani, Lorenzo, Manzoli, Lamberto
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2020
Elsevier BV
Subjects
Age Factors
Betacoronavirus - pathogenicity
Communicable Disease Control - methods
Communicable Disease Control - organization & administration
Containment
Containment policies
Coronavirus Infections - epidemiology
Coronavirus Infections - mortality
Coronavirus Infections - prevention & control
Coronavirus Infections - transmission
COVID-19
COVID-19 - epidemiology
COVID-19 - mortality
COVID-19 - prevention & control
COVID-19 - transmission
Diagnostic systems
Diagnostic tests
Epidemiology
Humans
Incidence
Italy - epidemiology
Lethality
Masks
Models, Statistical
Mortality
Pandemics
Pandemics - prevention & control
Patient Isolation - methods
Patient Isolation - organization & administration
Physical Distancing
Pneumonia, Viral - epidemiology
Pneumonia, Viral - mortality
Pneumonia, Viral - prevention & control
Pneumonia, Viral - transmission
Quarantine - ethics
Quarantine - methods
Quarantine - organization & administration
Risk Factors
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Severity of Illness Index
Survival Analysis
Viral diseases
Viruses
Italy
COVID-19
Containment policies
SARS-CoV-2
Epidemiology
Diagnostic tests
Mortality
Online AccessGet full text
ISSN2212-4926
2212-4934
2212-4934
DOI10.1016/j.jbior.2020.100736

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Abstract By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, lethality, and containment policies. We provide an updated summary of the current knowledge on the pandemic, discussing the available evidence on the effectiveness of the adopted mitigation strategies.
AbstractList By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, lethality, and containment policies. We provide an updated summary of the current knowledge on the pandemic, discussing the available evidence on the effectiveness of the adopted mitigation strategies.By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, lethality, and containment policies. We provide an updated summary of the current knowledge on the pandemic, discussing the available evidence on the effectiveness of the adopted mitigation strategies.
By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, lethality, and containment policies. We provide an updated summary of the current knowledge on the pandemic, discussing the available evidence on the effectiveness of the adopted mitigation strategies.
ArticleNumber 100736
Author Flacco, Maria Elena
Mantovani, Lorenzo
Cappadona, Rosaria
Acuti Martellucci, Cecilia
Bravi, Francesca
Manzoli, Lamberto
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  orcidid: 0000-0002-4308-2144
  surname: Acuti Martellucci
  fullname: Acuti Martellucci, Cecilia
  organization: Section of Hygiene and Preventive Medicine, Department of Biomedical Sciences and Public Health, University of the Marche Region, Via Conca, 60126, Ancona, Italy
– sequence: 2
  givenname: Maria Elena
  orcidid: 0000-0003-1404-4314
  surname: Flacco
  fullname: Flacco, Maria Elena
  organization: Department of Medical Sciences, University of Ferrara, Via Fossato di Mortara 64/B, 44121, Ferrara, Italy
– sequence: 3
  givenname: Rosaria
  surname: Cappadona
  fullname: Cappadona, Rosaria
  organization: Department of Medical Sciences, University of Ferrara, Via Fossato di Mortara 64/B, 44121, Ferrara, Italy
– sequence: 4
  givenname: Francesca
  surname: Bravi
  fullname: Bravi, Francesca
  organization: “Sant'Anna” University Hospital of Ferrara, Via Aldo Moro 8, 44124, Cona (Fe), Italy
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  orcidid: 0000-0003-3866-8199
  surname: Mantovani
  fullname: Mantovani, Lorenzo
  organization: University Bicocca, Piazza dell'Ateneo Nuovo, 1, 20126, Milan, Italy
– sequence: 6
  givenname: Lamberto
  orcidid: 0000-0002-8129-9344
  surname: Manzoli
  fullname: Manzoli, Lamberto
  email: lmanzoli@post.harvard.edu
  organization: Department of Medical Sciences, University of Ferrara, Via Fossato di Mortara 64/B, 44121, Ferrara, Italy
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32773099$$D View this record in MEDLINE/PubMed
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Keywords COVID-19
Containment policies
SARS-CoV-2
Epidemiology
Diagnostic tests
Mortality
Language English
License Copyright © 2020. Published by Elsevier Ltd.
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
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Snippet By the end of May 2020, SARS-CoV-2 pandemic caused more than 350,000 deaths worldwide. In the first months, there have been uncertainties on almost any area:...
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SubjectTerms Age Factors
Betacoronavirus - pathogenicity
Communicable Disease Control - methods
Communicable Disease Control - organization & administration
Containment
Containment policies
Coronavirus Infections - epidemiology
Coronavirus Infections - mortality
Coronavirus Infections - prevention & control
Coronavirus Infections - transmission
COVID-19
COVID-19 - epidemiology
COVID-19 - mortality
COVID-19 - prevention & control
COVID-19 - transmission
Diagnostic systems
Diagnostic tests
Epidemiology
Humans
Incidence
Italy - epidemiology
Lethality
Masks
Models, Statistical
Mortality
Pandemics
Pandemics - prevention & control
Patient Isolation - methods
Patient Isolation - organization & administration
Physical Distancing
Pneumonia, Viral - epidemiology
Pneumonia, Viral - mortality
Pneumonia, Viral - prevention & control
Pneumonia, Viral - transmission
Quarantine - ethics
Quarantine - methods
Quarantine - organization & administration
Risk Factors
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Severity of Illness Index
Survival Analysis
Viral diseases
Viruses
Title SARS-CoV-2 pandemic: An overview
URI https://dx.doi.org/10.1016/j.jbior.2020.100736
https://www.ncbi.nlm.nih.gov/pubmed/32773099
https://www.proquest.com/docview/2447303882
https://www.proquest.com/docview/2432861174
https://pubmed.ncbi.nlm.nih.gov/PMC7832554
Volume 77
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