Recent Advances in Separation of Bioactive Natural Products

Bioactive natural products are a main source of new drugs, functional foods and food additives. The separation of bioactive natural products plays an important role in transformation and use of biomass. The isolation and purification of bioactive_principle from a complex matrix is often inherent bot...

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Published inChinese journal of chemical engineering Vol. 21; no. 9; pp. 937 - 952
Main Author 任其龙 邢华斌 鲍宗必 苏宝根 杨启炜 杨亦文 张治国
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.09.2013
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ISSN1004-9541
2210-321X
DOI10.1016/S1004-9541(13)60560-1

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Summary:Bioactive natural products are a main source of new drugs, functional foods and food additives. The separation of bioactive natural products plays an important role in transformation and use of biomass. The isolation and purification of bioactive_principle from a complex matrix is often inherent bottleneck for the utilization of natural products, so a series of extraction and separation techniques have been developed. This review covers recent advances in the separation of bioactive natural products with an emphasis on their solubility and diffusion coefficients, recent extraction techniques and isolation techniques. This overview of recent technological advances, dis- cussion of pertinent problems and prospect of current methodologies in the separation of bioactive natural products may provide a driving force for development of novel separation techniques.
Bibliography:biomass, chromatography. extraction, isolation, natural products
11-3270/TQ
Bioactive natural products are a main source of new drugs, functional foods and food additives. The separation of bioactive natural products plays an important role in transformation and use of biomass. The isolation and purification of bioactive_principle from a complex matrix is often inherent bottleneck for the utilization of natural products, so a series of extraction and separation techniques have been developed. This review covers recent advances in the separation of bioactive natural products with an emphasis on their solubility and diffusion coefficients, recent extraction techniques and isolation techniques. This overview of recent technological advances, dis- cussion of pertinent problems and prospect of current methodologies in the separation of bioactive natural products may provide a driving force for development of novel separation techniques.
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ISSN:1004-9541
2210-321X
DOI:10.1016/S1004-9541(13)60560-1