A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study - Harrison, Stephen A; Ratziu, Vlad; Boursier, Jérôme; Francque, Sven; Bedossa, Pierre; Majd, Zouher; Cordonnier, Geneviève; Sudrik, Fouad Ben; Darteil, Raphael; Liebe, Roman; Magnanensi, Jérémy; Hajji, Yacine; et al. (The lancet. Gastroenterology & hepatology, 2020)
Keywords: alpha-Macroglobulins - analysis; Area Under Curve; Biomarkers - blood; Biopsy - methods; Chitinase-3-Like Protein 1 - analysis; Clinical Chemistry Tests - methods; Clinical Chemistry Tests - standards; Clinical Decision Rules; Disease Progression; Elasticity Imaging Techniques - methods; Glycated Hemoglobin A - analysis; Humans; Liver - metabolism; Liver - pathology; Liver Cirrhosis - blood; Liver Cirrhosis - diagnosis; MicroRNAs - analysis; Non-alcoholic Fatty Liver Disease - blood; Non-alcoholic Fatty Liver Disease - diagnosis; Patient Acuity; Predictive Value of Tests; Risk Assessment - methods