Approach for Phased Sequence-Based Genotyping of the Critical Pharmacogene Dihydropyrimidine Dehydrogenase (DPYD) - Ambrodji, Alisa; Sadlon, Angélique; Amstutz, Ursula; Hoch, Dennis; Berger, Martin D.; Bastian, Sara; Offer, Steven M.; Largiadèr, Carlo R. (International journal of molecular sciences, 2024)
Keywords: Alleles; Dehydrogenases; Dihydrouracil Dehydrogenase (NADP) - genetics; Ethylenediaminetetraacetic acid; Genes; Genetic aspects; Genotype; Genotype & phenotype; Genotyping Techniques - methods; Haplotypes; High-Throughput Nucleotide Sequencing - methods; Humans; Neoplasms - genetics; Polymorphism, Single Nucleotide; Scientific equipment and supplies industry; Sequence Analysis, DNA - methods; Single nucleotide polymorphisms; Toxicity; United Kingdom; United States; Massachusetts; Germany; rare variants; Oxford Nanopore Technologies sequencing; haplotype; long-range amplicon; pharmacogenomics; DPYD; PCR chimera; fluoropyrimidines; compound heterozygous