The application of fluid dynamic gauging in characterising cake deposition during the cross-flow microfiltration of a yeast suspension

► Cake thickness was measured in situ and in real time during microfiltration. ► FDG was used to estimate thickness and cohesive strength of yeast cakes. ► Yeast cakes of thickness ca. 255 and 250μm were identified after 30min fouling. ► The cake's resilience to fluid shear was inversely propor...

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Published inJournal of membrane science Vol. 405-406; pp. 113 - 122
Main Authors Lewis, William J.T., Chew, Y.M. John, Bird, Michael R.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.07.2012
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ISSN0376-7388
1873-3123
DOI10.1016/j.memsci.2012.02.065

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Abstract ► Cake thickness was measured in situ and in real time during microfiltration. ► FDG was used to estimate thickness and cohesive strength of yeast cakes. ► Yeast cakes of thickness ca. 255 and 250μm were identified after 30min fouling. ► The cake's resilience to fluid shear was inversely proportional to its thickness. ► After erosion, a persistent cake layer resistant to stresses >30Pa was identified. Fluid dynamic gauging (FDG) has been used to study cake fouling during cross-flow microfiltration of inactive Saccharomyces cerevisiae yeast suspensions through a 5μm nominal pore size mixed cellulose ester membrane. Cake thickness was measured in situ and in real-time during fouling, for which an initial growth rate of ca. 0.81μms−1 was observed at TMP=35mbar and Reduct=1000. The thickness increased asymptotically to a terminal value of 130μm, limited by the FDG process. Although it influences the evolution of the cake thickness, FDG can nevertheless be used to perform strength tests on preformed cakes, by imposing controlled shear stresses to the surface and measuring the thickness following deformation. Cake deformation via incremental increases in shear stress demonstrated that the cake's resilience to tangential fluid shear was inversely proportional to its thickness. It was found that preformed cakes over 250μm thick were deformed by shear stresses <10Nm−2, indicating very loose cohesion between cells on the cake's surface. The range and accuracy of thickness measurements is subject to the strength of fouling layers and the operating conditions of the apparatus. Measures to enhance the technique's efficacy have been identified and are currently underway.
AbstractList Fluid dynamic gauging (FDG) has been used to study cake fouling during cross-flow microfiltration of inactive Saccharomyces cerevisiae yeast suspensions through a 5 mu m nominal pore size mixed cellulose ester membrane. Cake thickness was measured in situ and in real-time during fouling, for which an initial growth rate of ca. 0.81 mu m s-1 was observed at TMP = 35 mbar and Reduct = 1000. The thickness increased asymptotically to a terminal value of 130 mu m, limited by the FDG process. Although it influences the evolution of the cake thickness, FDG can nevertheless be used to perform strength tests on preformed cakes, by imposing controlled shear stresses to the surface and measuring the thickness following deformation. Cake deformation via incremental increases in shear stress demonstrated that the cake's resilience to tangential fluid shear was inversely proportional to its thickness. It was found that preformed cakes over 250 mu m thick were deformed by shear stresses <10 N m-2, indicating very loose cohesion between cells on the cake's surface. The range and accuracy of thickness measurements is subject to the strength of fouling layers and the operating conditions of the apparatus. Measures to enhance the technique's efficacy have been identified and are currently underway.
Fluid dynamic gauging (FDG) has been used to study cake fouling during cross-flow microfiltration of inactive Saccharomyces cerevisiae yeast suspensions through a 5μm nominal pore size mixed cellulose ester membrane. Cake thickness was measured in situ and in real-time during fouling, for which an initial growth rate of ca. 0.81μms⁻¹ was observed at TMP=35mbar and Redᵤcₜ=1000. The thickness increased asymptotically to a terminal value of 130μm, limited by the FDG process. Although it influences the evolution of the cake thickness, FDG can nevertheless be used to perform strength tests on preformed cakes, by imposing controlled shear stresses to the surface and measuring the thickness following deformation. Cake deformation via incremental increases in shear stress demonstrated that the cake's resilience to tangential fluid shear was inversely proportional to its thickness. It was found that preformed cakes over 250μm thick were deformed by shear stresses <10Nm⁻², indicating very loose cohesion between cells on the cake's surface. The range and accuracy of thickness measurements is subject to the strength of fouling layers and the operating conditions of the apparatus. Measures to enhance the technique's efficacy have been identified and are currently underway.
► Cake thickness was measured in situ and in real time during microfiltration. ► FDG was used to estimate thickness and cohesive strength of yeast cakes. ► Yeast cakes of thickness ca. 255 and 250μm were identified after 30min fouling. ► The cake's resilience to fluid shear was inversely proportional to its thickness. ► After erosion, a persistent cake layer resistant to stresses >30Pa was identified. Fluid dynamic gauging (FDG) has been used to study cake fouling during cross-flow microfiltration of inactive Saccharomyces cerevisiae yeast suspensions through a 5μm nominal pore size mixed cellulose ester membrane. Cake thickness was measured in situ and in real-time during fouling, for which an initial growth rate of ca. 0.81μms−1 was observed at TMP=35mbar and Reduct=1000. The thickness increased asymptotically to a terminal value of 130μm, limited by the FDG process. Although it influences the evolution of the cake thickness, FDG can nevertheless be used to perform strength tests on preformed cakes, by imposing controlled shear stresses to the surface and measuring the thickness following deformation. Cake deformation via incremental increases in shear stress demonstrated that the cake's resilience to tangential fluid shear was inversely proportional to its thickness. It was found that preformed cakes over 250μm thick were deformed by shear stresses <10Nm−2, indicating very loose cohesion between cells on the cake's surface. The range and accuracy of thickness measurements is subject to the strength of fouling layers and the operating conditions of the apparatus. Measures to enhance the technique's efficacy have been identified and are currently underway.
Author Chew, Y.M. John
Bird, Michael R.
Lewis, William J.T.
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Keywords CFD
NIR-NLOI
CFMF
Fouling
Yeast
DOTM
SSE
EPSRC
FDG
UTDR
Cleaning
Fluid dynamic gauging
Microfiltration
NMR
MF
SEM
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Snippet ► Cake thickness was measured in situ and in real time during microfiltration. ► FDG was used to estimate thickness and cohesive strength of yeast cakes. ►...
Fluid dynamic gauging (FDG) has been used to study cake fouling during cross-flow microfiltration of inactive Saccharomyces cerevisiae yeast suspensions...
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StartPage 113
SubjectTerms artificial membranes
cellulose
Cleaning
cohesion
deformation
Fluid dynamic gauging
Fouling
Microfiltration
porosity
Saccharomyces cerevisiae
shear stress
Yeast
yeasts
Title The application of fluid dynamic gauging in characterising cake deposition during the cross-flow microfiltration of a yeast suspension
URI https://dx.doi.org/10.1016/j.memsci.2012.02.065
https://www.proquest.com/docview/1028024580
https://www.proquest.com/docview/1803084156
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