Potential respiratory pathogens colonisation of the denture plaque of patients with chronic obstructive pulmonary disease

• Published in: Gerodontology Vol. 33; no. 3; pp. 322 - 327
• Main Authors: Przybyłowska, Dorota, Mierzwińska-Nastalska, Elżbieta, Swoboda-Kopeć, Ewa, Rubinsztajn, Renata, Chazan, Ryszarda
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.09.2016
• Subjects: Aged; Aged, 80 and over; Bacteria - growth & development; Bacteria - isolation & purification; Biofilms; Candida; Dental Plaque - microbiology; denture plaque; denture stomatitis; Dentures - microbiology; Female; Fungi - growth & development; Fungi - isolation & purification; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive - microbiology; respiratory pathogens; denture plaque; respiratory pathogens; Candida; denture stomatitis
• ISSN: 0734-0664; 1741-2358; 1741-2358
• DOI: 10.1111/ger.12156

Introduction The role of bacterial infections in acute exacerbations of chronic obstructive pulmonary disease (COPD) is widely examined. Denture plaque in patients with COPD is an example of bacterial and fungal biofilm, which is a reservoir of potentially pathogenic respiratory tract microorganisms. Poor denture hygiene might cause acute exacerbations of COPD. Objective Assessment of prevalence of respiratory tract pathogens in denture plaque in stable patients with COPD and it influence on oral ontocenoses depending upon the therapy. Materials and methods The study was based on the clinical assessment of oral mucosa and denture hygiene in 53 patients with COPD with mean age of 70 ± 18 years and 14 generally healthy participants with mean age of 65 ± 14 years. Microbiological and mycological tests were performed by culturing direct denture swabs. Results The study showcased the presence of potential pathogenic micro‐organisms in denture plaque of 48 patients with COPD (90%) and nine healthy subjects (64.3%). Yeast‐like fungi prevailed in denture surface swabs of 40 (75%) in patients with COPD and 8 (57%) in cases of control group. In 66% of patients, various degree of oral mucosa inflammation prevailed. Conclusions Denture plaque could be a potential source of bacterial and fungal infections in patients with COPD.