Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression - Deng, Ruyuan; Wu, Huo; Ran, Hui; Kong, Xiang; Hu, Lei; Wang, Xiao; Su, Qing (Biochimica et biophysica acta. General subjects, 2017)
Keywords: advanced glycation end products; AGEs; antibodies; blood serum; Caco-2 Cells; Cell Line, Tumor; Cell Movement - physiology; Chinese people; Colorectal cancer; colorectal neoplasms; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Diabetes Mellitus - metabolism; Diabetes Mellitus - pathology; diabetic complications; dose response; Female; Glucose - metabolism; Glycation End Products, Advanced - metabolism; HCT116 Cells; HT29 Cells; Humans; in vitro studies; Invasion; lymph nodes; Male; MAP Kinase Signaling System - physiology; Matrix Metalloproteinase 2 - metabolism; metastasis; Middle Aged; Migration; mitogen-activated protein kinase; Neoplasm Invasiveness - genetics; Neoplasm Invasiveness - pathology; patients; phosphorylation; Phosphorylation - physiology; RAGE; risk; RNA, Small Interfering - metabolism; small interfering RNA; Sp1; Sp1 Transcription Factor - metabolism; tissues; Up-Regulation - genetics; AGEs; RAGE; Sp1; Migration; Invasion; Colorectal cancer