Rationally designed hypoallergenic mutant variants of the house dust mite allergen Der p 21 - Santos, Sara P.O.; Lisboa, Ayrton B.P.; Silva, Filipe S.R.; Tiwari, Sandeep; Azevedo, Vasco; Cruz, Álvaro A.; Silva, Eduardo S.; Pinheiro, Carina S.; Alcantara-Neves, Neuza M.; Pacheco, Luis G.C. (Biochimica et biophysica acta. General subjects, 2022)
Keywords: Allergen engineering; Allergen-specific immunotherapy; allergens; Allergens - genetics; amino acids; Animals; Antigens, Dermatophagoides - chemistry; Antigens, Dermatophagoides - genetics; Arthropod Proteins - genetics; computer simulation; Der p 21; Dermatophagoides pteronyssinus; dust mites; epitopes; Humans; Hypersensitivity - genetics; immune response; Immunoglobulin E - genetics; Immunoinformatics; immunotherapy; mutagenesis; mutants; Pyroglyphidae - genetics; Pyroglyphidae - metabolism; Recombinant hypoallergen; Der p 21; Allergen-specific immunotherapy; Recombinant hypoallergen; Allergen engineering; Dermatophagoides pteronyssinus; Immunoinformatics