The role of frataxin in fission yeast iron metabolism: Implications for Friedreich's ataxia - Wang, Yu; Wang, Yiwei; Marcus, S.; Busenlehner, L.S. (Biochimica et biophysica acta, 2014)
Keywords: ataxia (disorder); biogenesis; cell respiration; enzymes; Frataxin; Friedreich Ataxia - genetics; Friedreich Ataxia - metabolism; Friedreich's ataxia; Fungal Proteins - genetics; Fungal Proteins - metabolism; gene overexpression; iron; Iron - metabolism; iron absorption; Iron homeostasis; Iron-Binding Proteins - biosynthesis; Iron-Binding Proteins - genetics; Iron–sulfur cluster; mitochondria; mitochondrial membrane; Mitochondrial Membranes - metabolism; neurodegenerative diseases; oxidative stress; Oxidative Stress - genetics; phenotype; plasmids; Schizosaccharomyces - genetics; Schizosaccharomyces - metabolism; Schizosaccharomyces pombe; Sequence Homology, Amino Acid; stress response; thiamin; Up-Regulation; Isd11; Isu1; BPS; Fxn1Δ2–11; Frp1; DFO; CyaY; nmt1; NADP+/NADPH; Iron–sulfur cluster; Nfs1; Frataxin; Fe–S; Yfh1; SDH2; Iron homeostasis; BCA; DTPA; hFxn; EMM; MALDI-TOF; qRT-PCR; SOD; Friedreich's ataxia; TCA; PMS; ROS; DCIP; FA; sdh2-GFP