Crystal structure and substrate specificity of ExoY, a unique T3SS mediated secreted nucleotidyl cyclase toxin from Pseudomonas aeruginosa - Khanppnavar, Basavraj; Datta, Saumen (Biochimica et biophysica acta. General subjects, 2018)
Keywords: anthrax; Anthrax toxA family; Bacterial Proteins - chemistry; Bacterial Proteins - metabolism; Biological Transport; calorimetry; catalytic activity; chronic diseases; crystal structure; crystallization; Crystallography, X-Ray; cyclic AMP; cyclic GMP; Cyclic GMP - metabolism; Glucosyltransferases - chemistry; Glucosyltransferases - metabolism; Non-canonical secondary messengers; Nucleotidyl cyclase toxins; One-metal-ion dependent catalysis; Protein Conformation; proteinases; proteolysis; Pseudomonas aeruginosa; Pseudomonas aeruginosa - growth & development; Pseudomonas aeruginosa - metabolism; Pseudomonas Infections - microbiology; second messengers; Signal Transduction; Substrate Specificity; T3SS; Toxins, Biological - chemistry; Toxins, Biological - metabolism; virulence; X-ray crystallography; cNMP; GTP; cIMP; cGMP; DLS; Anthrax toxA family; cAMP; cCMP; X-ray crystallography; UTP; Pa; TAK1; MD; T3SS; cUMP; RRCAT; Vv; EF; MR; Nucleotidyl cyclase toxins; RMSD; AA-NC; SEC; SDS-PAGE; IPTG; ITC; One-metal-ion dependent catalysis; NTA; Non-canonical secondary messengers; ExoY; ATP; CTP