Dependence of HSP27 cellular level on protein kinase CK2 discloses novel therapeutic strategies - Borgo, Christian; Vilardell, Jordi; Bosello-Travain, Valentina; Pinna, Lorenzo A.; Venerando, Andrea; Salvi, Mauro (Biochimica et biophysica acta. General subjects, 2018)
Keywords: ABC transporters; adenosine triphosphate; Animals; apoptosis; atherosclerosis; Cancer; Casein Kinase II - antagonists & inhibitors; Casein Kinase II - metabolism; Catalysis; Cell Line; cell lines; cystic fibrosis; drug resistance; drugs; enzyme inhibitors; fever; fluorescence microscopy; gene editing; HSP27 Heat-Shock Proteins - metabolism; HSP27, SMURF2; Humans; ischemia; metastasis; Mice; mothers against decapentaplegic homolog proteins; neoplasm cells; neoplasms; neurodegenerative diseases; precipitin tests; Protein kinase CK2; Protein Kinase Inhibitors - pharmacology; protein kinases; Proteomics; small interfering RNA; Substrate Specificity; therapeutics; Thermotherapy; ubiquitin-protein ligase; Ubiquitin-Protein Ligases - metabolism; Ubiquitination; CX-4945; HSF-1; Protein kinase CK2; HSP; SMURF2; BMP; PDCD5; QZ; siRNA; Thermotherapy; TDB; IC50; HSP27, SMURF2; TGF-β; EC50; CFTR; Cancer