Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer - Bhattacharjee, Mousumi; Upadhyay, Priyanka; Sarker, Sushmita; Basu, Arijita; Das, Shaswati; Ghosh, Avijit; Ghosh, Swatilekha; Adhikary, Arghya (Biochimica et biophysica acta. General subjects, 2020)
Keywords: antineoplastic activity; antineoplastic agents; Antineoplastic Agents - pharmacology; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Apoptosis; Apoptosis - drug effects; Benzoquinones - pharmacology; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - pathology; cell cycle checkpoints; cell movement; Cell Movement - drug effects; Cell Proliferation - drug effects; Combinatorial therapy; cytotoxicity; drug resistance; Drug Synergism; Emodin; Emodin - pharmacology; Female; flow cytometry; human cell lines; Humans; immunocytochemistry; MCF-7 Cells; Migration; mononuclear leukocytes; Neoplastic Stem Cells - drug effects; Neoplastic Stem Cells - pathology; patients; phytochemicals; Protein Kinase Inhibitors - pharmacology; regulatory proteins; remission; synergism; Thymoquinone; tissue repair; viability assays; xenotransplantation; Migration; CI; Emo; Thymoquinone; Cyt C; DAPI; Breast cancer; FACS; MTT; MFE; Emodin; Combinatorial therapy; ROS; SEM; TNBC; TRITC; TQ; Apoptosis; CSCs