Comparative study of Scleromitrion diffusum and Oldenlandia corymbosa: Microscopy, TLC, HPLC, and antioxidant activity
Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This stud...
Saved in:
| Published in | Microscopy research and technique Vol. 87; no. 10; pp. 2371 - 2384 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Hoboken, USA
John Wiley & Sons, Inc
01.10.2024
Wiley Subscription Services, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1059-910X 1097-0029 1097-0029 |
| DOI | 10.1002/jemt.24611 |
Cover
| Abstract | Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin‐layer chromatography (TLC), and high‐pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenging effect, 2,2′‐azino‐bis 3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS•+) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market.
Research Highlights
The study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa – a common adulterant species of S. diffusum on the Taiwan markets.
Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa.
Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS•+ scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa.
Comparative study of Scleromitrion diffusum and Oldenlandia corymbosa: microscopy, TLC, HPLC and antioxidant activity. |
|---|---|
| AbstractList | Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin‐layer chromatography (TLC), and high‐pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenging effect, 2,2′‐azino‐bis 3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS•+) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market.
Research Highlights
The study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa – a common adulterant species of S. diffusum on the Taiwan markets.
Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa.
Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS•+ scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa.
Comparative study of Scleromitrion diffusum and Oldenlandia corymbosa: microscopy, TLC, HPLC and antioxidant activity. Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin-layer chromatography (TLC), and high-pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging effect, 2,2'-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market. RESEARCH HIGHLIGHTS: The study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa - a common adulterant species of S. diffusum on the Taiwan markets. Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa. Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS•+ scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa.Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin-layer chromatography (TLC), and high-pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging effect, 2,2'-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market. RESEARCH HIGHLIGHTS: The study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa - a common adulterant species of S. diffusum on the Taiwan markets. Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa. Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS•+ scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa. Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin‐layer chromatography (TLC), and high‐pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenging effect, 2,2′‐azino‐bis 3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS•+) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market.Research HighlightsThe study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa – a common adulterant species of S. diffusum on the Taiwan markets.Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa.Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS•+ scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa. Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which can affect efficacy or cause toxicity. Scleromitrion diffusum is a common herb, yet it is often mistaken for Oldenlandia corymbosa. This study analyzed the morphology, microscopy, thin-layer chromatography (TLC), and high-pressure liquid chromatography (HPLC) using two markers, asperuloside and scandoside methyl ester, to distinguish between S. diffusum and O. corymbosa with the analysis included 10 samples of S. diffusum and 10 samples of O. corymbosa collected from the Taiwan market. By quantifying the total polyphenols and flavonoids, we investigated the antioxidant activity, including the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging effect, 2,2'-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS ) scavenging effect, and reducing power to further elucidate the biological effects of the two herbs. The results of this study revealed notable differences in microscopy and suggested a TLC method for distinguishing between the two herbs in the market. In HPLC, the ratios of asperuloside and scandoside methyl ester differed between the two herbs. S. diffusum contained a higher asperuloside content. In contrast, O. corymbosa contained higher concentrations of scandoside methyl esters. With more total polyphenols and flavonoids in S. diffusum than those in O. corymbosa, the antioxidant activity of S. diffusum was superior to that of O. corymbosa. This study provides a comprehensive understanding for the identification and quality evaluation of S. diffusum in the market. RESEARCH HIGHLIGHTS: The study consolidates and clarifies the morphological and microscopic differences between Scleromitrion diffusum and Oldenlandia corymbosa - a common adulterant species of S. diffusum on the Taiwan markets. Using Asperuloside and Scandoside methyl ester as two chemical markers, the study proposes a TLC method for rapidly testing S. diffusum and O. corymbosa on the market. Through HPLC analysis, our results showed that S. diffusum and O. corymbosa had a clear difference in the ratio of two markers, Asperuloside and Scandoside methyl ester: Asperuloside/Scandoside methyl ester in S. diffusum is higher than that in O. corymbosa. Through phytochemicals contents, including total phenols content, flavonoids content, and antioxidant activity, including DPPH, ABTS scavenging activity, and reducing power, S. diffusum showed slightly higher levels of phenols and flavonoids as well as a better antioxidant activity than O. corymbosa. |
| Author | Chang, Yuan‐Shiun Au, Thanh‐Thuy‐Dung Ho, Yu‐Ling Wu, Kun‐Chang Wu, Hung‐Yi |
| Author_xml | – sequence: 1 givenname: Yu‐Ling surname: Ho fullname: Ho, Yu‐Ling organization: Hungkuang University – sequence: 2 givenname: Thanh‐Thuy‐Dung surname: Au fullname: Au, Thanh‐Thuy‐Dung organization: China Medical University – sequence: 3 givenname: Hung‐Yi surname: Wu fullname: Wu, Hung‐Yi organization: Min Tong Pharmaceutical Company – sequence: 4 givenname: Kun‐Chang surname: Wu fullname: Wu, Kun‐Chang organization: China Medical University – sequence: 5 givenname: Yuan‐Shiun orcidid: 0000-0002-8149-2638 surname: Chang fullname: Chang, Yuan‐Shiun email: yschang0404@mail.edu.tw organization: China Medical University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38808861$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kU9r3DAQxUVJaP60l36AIugllDiVLNmWeitL0qRsSKFb6E3I0hi02NZWkpP620fuJpdQetEM4vdmpPdO0MHoR0DoHSUXlJDy0xaGdFHymtJX6JgS2RT5Vh4sfSULScmvI3QS45YQSivKX6MjJgQRoqbH6H7lh50OOrl7wDFNdsa-wz9MD8EPLgXnR2xd101xGrAeLb7rLYx97pzGxod5aH3Un_GtM8FH43fzOd6sV-f4-vtyLgo9Juf_OJsr1iYvcml-gw473Ud4-1RP0c-ry83quljffb1ZfVkXhklGC1E2ttIdYSXU1OhKA2-Ethwkr0E0kjHZlmVnGCm1kMbotuG8laSmvBXALDtFZ_u5u-B_TxCTGlw00OcPgJ-iYhltBBNVndEPL9Ctn8KYX5cpKUvBq6rJ1PsnamoHsGoX3KDDrJ4dzQDZA4sfMUCnjEvZXj-moF2vKFFLaGoJTf0NLUs-vpA8T_0nTPfwg-th_g-pvl3ebvaaRw3Np1w |
| CitedBy_id | crossref_primary_10_1186_s13020_025_01061_w |
| Cites_doi | 10.1002/cbdv.202100685 10.11653/syfj2014010063 10.1016/j.foodchem.2007.02.023 10.1016/j.phymed.2022.154070 10.3109/13880209.2015.1056310 10.1016/j.isci.2020.101522 10.1016/j.phymed.2008.01.003 10.3892/ol.2017.7244 10.1007/s11418-007-0212-1 10.3389/fphar.2021.624296 10.1248/cpb.54.1131 10.3390/app11199073 10.1055/s-2007-990259 10.1006/abio.1996.0292 10.3390/antiox11020335 10.1016/j.jep.2019.01.004 10.3321/j.issn:1001-5213.2007.02.064 10.3389/fendo.2021.615446 10.1002/tax.12488 10.1016/j.phymed.2022.154319 10.3390/molecules21060710 10.1078/094471103321659898 10.1002/jemt.20312 10.1016/j.jep.2022.115597 10.1016/j.archoralbio.2021.105199 10.1016/j.bse.2015.06.028 10.3390/plants10010161 10.1002/jssc.201100780 10.1016/j.jep.2016.07.027 10.3390/molecules23071525 |
| ContentType | Journal Article |
| Copyright | 2024 The Authors. published by Wiley Periodicals LLC. 2024 The Authors. Microscopy Research and Technique published by Wiley Periodicals LLC. 2024. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2024 The Authors. published by Wiley Periodicals LLC. – notice: 2024 The Authors. Microscopy Research and Technique published by Wiley Periodicals LLC. – notice: 2024. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | 24P AAYXX CITATION NPM 7QF 7QO 7QP 7QQ 7SC 7SE 7SP 7SR 7SS 7TA 7TB 7U5 7U7 8BQ 8FD C1K F28 FR3 H8D H8G JG9 JQ2 K9. KR7 L7M L~C L~D P64 RC3 7X8 |
| DOI | 10.1002/jemt.24611 |
| DatabaseName | Wiley Online Library Open Access CrossRef PubMed Aluminium Industry Abstracts Biotechnology Research Abstracts Calcium & Calcified Tissue Abstracts Ceramic Abstracts Computer and Information Systems Abstracts Corrosion Abstracts Electronics & Communications Abstracts Engineered Materials Abstracts Entomology Abstracts (Full archive) Materials Business File Mechanical & Transportation Engineering Abstracts Solid State and Superconductivity Abstracts Toxicology Abstracts METADEX Technology Research Database Environmental Sciences and Pollution Management ANTE: Abstracts in New Technology & Engineering Engineering Research Database Aerospace Database Copper Technical Reference Library Materials Research Database ProQuest Computer Science Collection ProQuest Health & Medical Complete (Alumni) Civil Engineering Abstracts Advanced Technologies Database with Aerospace Computer and Information Systems Abstracts Academic Computer and Information Systems Abstracts Professional Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed Materials Research Database Technology Research Database Computer and Information Systems Abstracts – Academic Mechanical & Transportation Engineering Abstracts ProQuest Computer Science Collection Computer and Information Systems Abstracts ProQuest Health & Medical Complete (Alumni) Materials Business File Environmental Sciences and Pollution Management Aerospace Database Copper Technical Reference Library Engineered Materials Abstracts Genetics Abstracts Biotechnology Research Abstracts Advanced Technologies Database with Aerospace ANTE: Abstracts in New Technology & Engineering Civil Engineering Abstracts Aluminium Industry Abstracts Toxicology Abstracts Electronics & Communications Abstracts Ceramic Abstracts METADEX Biotechnology and BioEngineering Abstracts Computer and Information Systems Abstracts Professional Entomology Abstracts Solid State and Superconductivity Abstracts Engineering Research Database Calcium & Calcified Tissue Abstracts Corrosion Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic Materials Research Database PubMed |
| Database_xml | – sequence: 1 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1097-0029 |
| EndPage | 2384 |
| ExternalDocumentID | 38808861 10_1002_jemt_24611 JEMT24611 |
| Genre | researchArticle Journal Article |
| GeographicLocations | Taiwan |
| GeographicLocations_xml | – name: Taiwan |
| GrantInformation_xml | – fundername: Chinese Materia Medica Standard Office, Department of Health, Hong Kong, SAR Government |
| GroupedDBID | --- -~X .3N .55 .GA .GJ .Y3 05W 0R~ 10A 123 1L6 1OB 1OC 1ZS 24P 31~ 33P 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHHS AAHQN AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABEFU ABEML ABIJN ABJNI ABPVW ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACIWK ACNCT ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFPM AFGKR AFPWT AFRAH AFWVQ AFZJQ AHBTC AHMBA AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ATUGU AUFTA AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BQCPF BROTX BRXPI BY8 CS3 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRSTM EBD EBS EJD EMOBN F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HBH HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M56 MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- OIG P2P P2W P2X P4D PALCI PQQKQ Q.N Q11 QB0 QRW R.K RIWAO ROL RWI RWR RX1 RYL SAMSI SUPJJ SV3 TWZ UB1 V2E W8V W99 WBKPD WHWMO WIB WIH WIK WJL WOHZO WQJ WRC WVDHM WXSBR WYB X7M XG1 XPP XV2 ZZTAW ~02 ~IA ~WT AAYXX AETEA AEYWJ AGHNM AGQPQ AGYGG CITATION NPM 7QF 7QO 7QP 7QQ 7SC 7SE 7SP 7SR 7SS 7TA 7TB 7U5 7U7 8BQ 8FD AAMMB AEFGJ AGXDD AIDQK AIDYY C1K F28 FR3 H8D H8G JG9 JQ2 K9. KR7 L7M L~C L~D P64 RC3 7X8 |
| ID | FETCH-LOGICAL-c3931-827d5af032e61ca5ae478ad4e946e879339b22fc302a89ccab744b90614b8e3d3 |
| IEDL.DBID | DR2 |
| ISSN | 1059-910X 1097-0029 |
| IngestDate | Thu Jul 10 17:23:23 EDT 2025 Fri Sep 12 03:31:49 EDT 2025 Thu Apr 03 07:09:14 EDT 2025 Thu Apr 24 23:01:35 EDT 2025 Tue Jul 01 01:27:06 EDT 2025 Wed Jan 22 17:14:41 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 10 |
| Keywords | Scleromitrion diffusum comparative study scandoside methyl ester asperuloside Oldenlandia corymbosa |
| Language | English |
| License | Attribution-NonCommercial-NoDerivs 2024 The Authors. Microscopy Research and Technique published by Wiley Periodicals LLC. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3931-827d5af032e61ca5ae478ad4e946e879339b22fc302a89ccab744b90614b8e3d3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-8149-2638 |
| OpenAccessLink | https://proxy.k.utb.cz/login?url=https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fjemt.24611 |
| PMID | 38808861 |
| PQID | 3099284557 |
| PQPubID | 1016375 |
| PageCount | 14 |
| ParticipantIDs | proquest_miscellaneous_3061783856 proquest_journals_3099284557 pubmed_primary_38808861 crossref_citationtrail_10_1002_jemt_24611 crossref_primary_10_1002_jemt_24611 wiley_primary_10_1002_jemt_24611_JEMT24611 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | October 2024 2024-10-00 2024-Oct 20241001 |
| PublicationDateYYYYMMDD | 2024-10-01 |
| PublicationDate_xml | – month: 10 year: 2024 text: October 2024 |
| PublicationDecade | 2020 |
| PublicationPlace | Hoboken, USA |
| PublicationPlace_xml | – name: Hoboken, USA – name: United States – name: New York |
| PublicationTitle | Microscopy research and technique |
| PublicationTitleAlternate | Microsc Res Tech |
| PublicationYear | 2024 |
| Publisher | John Wiley & Sons, Inc Wiley Subscription Services, Inc |
| Publisher_xml | – name: John Wiley & Sons, Inc – name: Wiley Subscription Services, Inc |
| References | 2022; 298 2007; 104 2006; 54 2021; 129 2016; 54 2008; 15 2006 2007; 73 2018; 23 2012; 35 2003; 10 2021; 70 1999 2014; 20 2022; 101 2021; 10 2021; 12 2010; 47 2021; 11 2017; 14 2022 2015; 62 2006; 69 2016; 21 2017 2015 2020; 23 2022; 11 2013 2012; 6 2008; 62 2016; 192 2022; 104 1996; 239 2019; 233 2022; 19 2009; 17 2007; 27 e_1_2_10_23_1 e_1_2_10_24_1 Rui‐chao L. (e_1_2_10_28_1) 2013 e_1_2_10_22_1 e_1_2_10_20_1 e_1_2_10_41_1 e_1_2_10_40_1 Yan C. (e_1_2_10_38_1) 2012; 6 e_1_2_10_2_1 e_1_2_10_18_1 e_1_2_10_3_1 e_1_2_10_19_1 e_1_2_10_16_1 Sasikumar J. M. (e_1_2_10_29_1) 2010; 47 e_1_2_10_39_1 e_1_2_10_17_1 e_1_2_10_8_1 e_1_2_10_14_1 e_1_2_10_37_1 e_1_2_10_7_1 e_1_2_10_15_1 e_1_2_10_36_1 e_1_2_10_12_1 e_1_2_10_35_1 e_1_2_10_9_1 e_1_2_10_13_1 e_1_2_10_34_1 e_1_2_10_10_1 e_1_2_10_33_1 e_1_2_10_11_1 Liang Z. T. (e_1_2_10_21_1) 2009; 17 e_1_2_10_32_1 Chang X. (e_1_2_10_4_1) 2006 e_1_2_10_31_1 e_1_2_10_30_1 Chang Y. S. (e_1_2_10_5_1) 2015 Chang Y. S. (e_1_2_10_6_1) 2017 e_1_2_10_27_1 e_1_2_10_25_1 e_1_2_10_26_1 |
| References_xml | – volume: 17 start-page: 69 issue: 2 year: 2009 end-page: 77 article-title: Determination of Oleanolic acid and Ursolic acid in and its substitute using high performance liquid chromatography publication-title: Journal of Food and Drug Analysis – volume: 19 issue: 2 year: 2022 article-title: Phytochemical composition and anti‐aging activity of butanol extract of in Caenorhabditis elegans publication-title: Chemistry & Biodiversity – volume: 47 start-page: 49 issue: 1 year: 2010 end-page: 52 article-title: In vitro antioxidant activity of (L.) Lam. Aerial parts publication-title: Indian Journal of Biochemistry and Biophysics – volume: 233 start-page: 169 year: 2019 end-page: 178 article-title: Comparative analysis of sixteen active compounds and antioxidant and anti‐influenza properties of Gardenia jasminoides fruits at different times and application to the determination of the appropriate harvest period with hierarchical cluster analysis publication-title: Journal of Ethnopharmacology – volume: 14 start-page: 8197 issue: 6 year: 2017 end-page: 8205 article-title: Willd. Extract suppresses colorectal cancer growth through multiple cellular pathways publication-title: Oncology Letters – volume: 11 issue: 19 year: 2021 article-title: In vivo and in vitro evaluation of preventive activity of inflammation and free radical scavenging potential of plant extracts from L publication-title: Applied Science‐Basel – volume: 21 issue: 6 year: 2016 article-title: The Willd. (Rubiaceae): A review on Phytochemistry, pharmacology, quality control and pharmacokinetics publication-title: Molecules – volume: 69 start-page: 277 issue: 4 year: 2006 end-page: 282 article-title: Distinguishing the medicinal herb from similar species of the same genus using fluorescence microscopy publication-title: Microscopy Research and Technique – volume: 54 start-page: 1148 issue: 7 year: 2016 end-page: 1155 article-title: Effect of water extract on protecting human hepatocyte cells (LO ) from H O ‐induced cytotoxicity publication-title: Pharmaceutical Biology – volume: 239 start-page: 70 issue: 1 year: 1996 end-page: 76 article-title: The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP assay publication-title: Analytical Biochemistry – volume: 12 year: 2021 article-title: The analyses of chemical components from (DC.) hand.‐Mazz and anticancer effects in vitro publication-title: Frontiers in Pharmacology – volume: 11 issue: 2 year: 2022 article-title: Chemical constituents of and their anti‐inflammatory bioactivities publication-title: Antioxidants – volume: 23 issue: 9 year: 2020 article-title: Asperuloside improves obesity and type 2 diabetes through modulation of gut microbiota and metabolic signaling publication-title: iScience – start-page: 355 year: 2015 end-page: 357 article-title: Illustrations of commonly misused Chinese crude drug species in Taiwan publication-title: Ministry of Health and Welfare – volume: 62 start-page: 249 issue: 2 year: 2008 end-page: 250 article-title: Chemical constituents from L. of Thai origin publication-title: Journal of Natural Medicines – volume: 298 year: 2022 article-title: The anti‐inflammatory effects of Willd on SLE with STAT3 as a key target publication-title: Journal of Ethnopharmacology – volume: 129 year: 2021 article-title: Asperuloside ameliorates lipopolysaccharide‐induced primary human periodontal ligament cell injury by decreasing TLR4 expression and NF‐KB activation publication-title: Archives of Oral Biology – volume: 35 start-page: 263 issue: 2 year: 2012 end-page: 272 article-title: Characterization and identification of iridoid glucosides, flavonoids and anthraquinones in by high‐performance liquid chromatography/electrospray ionization tandem mass spectrometry publication-title: Journal of Separation Science – volume: 10 issue: 1 year: 2021 article-title: Differentiation of and common adulterants based on chloroplast genome sequencing and DNA barcoding markers publication-title: Plants – volume: 70 start-page: 443 issue: 2 year: 2021 end-page: 444 article-title: (2813) proposal to conserve the name ( ) (Rubiaceae) with a conserved type publication-title: Taxon – volume: 6 start-page: 886 year: 2012 end-page: 892 article-title: Study on HPLC fingerprint of publication-title: Journal of Chinese Medicinal Materials – volume: 54 start-page: 1131 issue: 8 year: 2006 end-page: 1137 article-title: Determination of Iridoid glucosides for quality assessment of Herba Oldenlandiae by high‐performance liquid chromatography publication-title: Chemical and Pharmaceutical Bulletin – volume: 23 issue: 7 year: 2018 article-title: Discovery of the potential biomarkers for discrimination between and by UPLC‐QTOF/MS metabolome analysis publication-title: Molecules – start-page: 11 year: 2017 article-title: Consise identification Mannual for Chinese Materia Medica publication-title: Ministry of Health and Welfare – year: 2006 – volume: 10 start-page: 170 issue: 2–3 year: 2003 end-page: 175 article-title: Free radical‐scavenging activity of Taiwanese native plants publication-title: Phytomedicine – year: 2022 – volume: 15 start-page: 259 issue: 4 year: 2008 end-page: 267 article-title: A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs and and a new valuation of their biological potential publication-title: Phytomedicine – volume: 104 start-page: 1464 issue: 4 year: 2007 end-page: 1471 article-title: Antioxidant properties of and its simple coumarins publication-title: Food Chemistry – volume: 192 start-page: 132 year: 2016 end-page: 139 article-title: The anti‐tumor effect and bioactive phytochemicals of willd on ovarian cancer cells publication-title: Journal of Ethnopharmacology – volume: 20 start-page: 63 issue: 1 year: 2014 end-page: 65 article-title: Quality standard of in Qingshen granule publication-title: Chinese Journal of Experimental Traditional Medical Formulae – volume: 12 year: 2021 article-title: Asperuloside enhances taste perception and prevents weight gain in high‐fat fed mice publication-title: Front Endocrinol – volume: 62 start-page: 173 year: 2015 end-page: 177 article-title: A chemotaxonomic study of phytochemicals in publication-title: Biochemical Systematics and Ecology – volume: 73 start-page: 1502 issue: 14 year: 2007 end-page: 1508 article-title: Comparative analysis of and its substitutes by high performance liquid chromatographic fingerprint and mass spectrometric analysis publication-title: Planta Medica – volume: 27 start-page: 278 issue: 2 year: 2007 end-page: 279 article-title: Pharmaconostical identification of . Adulterated as publication-title: Chinese Journal of El Hospital Pharmacy – volume: 101 year: 2022 article-title: Asperuloside inhibited epithelial‐mesenchymal transition in colitis associated cancer via activation of vitamin D receptor publication-title: Phytomedicine – year: 2017 – volume: 104 year: 2022 article-title: injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma publication-title: Phytomedicine – year: 1999 – year: 2013 – volume: 47 start-page: 49 issue: 1 year: 2010 ident: e_1_2_10_29_1 article-title: In vitro antioxidant activity of Hedyotis corymbosa (L.) Lam. Aerial parts publication-title: Indian Journal of Biochemistry and Biophysics – ident: e_1_2_10_33_1 – ident: e_1_2_10_18_1 doi: 10.1002/cbdv.202100685 – volume-title: Handbook of chemical reference substance of natural products year: 2013 ident: e_1_2_10_28_1 – ident: e_1_2_10_16_1 doi: 10.11653/syfj2014010063 – start-page: 11 year: 2017 ident: e_1_2_10_6_1 article-title: Consise identification Mannual for Chinese Materia Medica publication-title: Ministry of Health and Welfare – ident: e_1_2_10_32_1 – ident: e_1_2_10_35_1 doi: 10.1016/j.foodchem.2007.02.023 – volume-title: Chinese herbal medicine test method series (XIII) identification of easily confused and misused raw Materials of Chinese medicine (II) year: 2006 ident: e_1_2_10_4_1 – ident: e_1_2_10_25_1 doi: 10.1016/j.phymed.2022.154070 – start-page: 355 year: 2015 ident: e_1_2_10_5_1 article-title: Illustrations of commonly misused Chinese crude drug species in Taiwan publication-title: Ministry of Health and Welfare – ident: e_1_2_10_11_1 doi: 10.3109/13880209.2015.1056310 – ident: e_1_2_10_26_1 doi: 10.1016/j.isci.2020.101522 – ident: e_1_2_10_19_1 doi: 10.1016/j.phymed.2008.01.003 – ident: e_1_2_10_10_1 doi: 10.3892/ol.2017.7244 – ident: e_1_2_10_8_1 – ident: e_1_2_10_27_1 doi: 10.1007/s11418-007-0212-1 – ident: e_1_2_10_41_1 doi: 10.3389/fphar.2021.624296 – ident: e_1_2_10_23_1 doi: 10.1248/cpb.54.1131 – ident: e_1_2_10_2_1 doi: 10.3390/app11199073 – ident: e_1_2_10_20_1 doi: 10.1055/s-2007-990259 – ident: e_1_2_10_3_1 doi: 10.1006/abio.1996.0292 – ident: e_1_2_10_14_1 doi: 10.3390/antiox11020335 – ident: e_1_2_10_30_1 doi: 10.1016/j.jep.2019.01.004 – ident: e_1_2_10_37_1 doi: 10.3321/j.issn:1001-5213.2007.02.064 – ident: e_1_2_10_15_1 doi: 10.3389/fendo.2021.615446 – ident: e_1_2_10_31_1 doi: 10.1002/tax.12488 – ident: e_1_2_10_13_1 doi: 10.1016/j.phymed.2022.154319 – ident: e_1_2_10_7_1 doi: 10.3390/molecules21060710 – ident: e_1_2_10_12_1 doi: 10.1078/094471103321659898 – ident: e_1_2_10_22_1 doi: 10.1002/jemt.20312 – volume: 17 start-page: 69 issue: 2 year: 2009 ident: e_1_2_10_21_1 article-title: Determination of Oleanolic acid and Ursolic acid in Oldenlandia diffusa and its substitute using high performance liquid chromatography publication-title: Journal of Food and Drug Analysis – ident: e_1_2_10_36_1 doi: 10.1016/j.jep.2022.115597 – ident: e_1_2_10_9_1 doi: 10.1016/j.archoralbio.2021.105199 – ident: e_1_2_10_17_1 doi: 10.1016/j.bse.2015.06.028 – volume: 6 start-page: 886 year: 2012 ident: e_1_2_10_38_1 article-title: Study on HPLC fingerprint of Oldenlandia diffusa publication-title: Journal of Chinese Medicinal Materials – ident: e_1_2_10_39_1 doi: 10.3390/plants10010161 – ident: e_1_2_10_24_1 doi: 10.1002/jssc.201100780 – ident: e_1_2_10_40_1 doi: 10.1016/j.jep.2016.07.027 – ident: e_1_2_10_34_1 doi: 10.3390/molecules23071525 |
| SSID | ssj0011514 |
| Score | 2.4452667 |
| Snippet | Quality control of herbal medicines is crucial, especially the role of herbal drug identification. This is essential for preventing the misuse of herbs, which... |
| SourceID | proquest pubmed crossref wiley |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 2371 |
| SubjectTerms | Antioxidants asperuloside Biological effects Chromatography Cocoa Comparative studies comparative study Esters Flavonoids Free radicals Herbal medicine Herbs High-performance liquid chromatography Liquid chromatography Microscopy Morphology Oldenlandia corymbosa Phenols Polyphenols Quality assessment Quality control scandoside methyl ester Scavenging Scleromitrion diffusum Species diffusion Sulfonic acid Toxicity |
| Title | Comparative study of Scleromitrion diffusum and Oldenlandia corymbosa: Microscopy, TLC, HPLC, and antioxidant activity |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fjemt.24611 https://www.ncbi.nlm.nih.gov/pubmed/38808861 https://www.proquest.com/docview/3099284557 https://www.proquest.com/docview/3061783856 |
| Volume | 87 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-NSUi88P3RMSYjeAEtXeuP2EG8oLKpmihM0El9QZGd2FJhTaY2RZS_nrukTTVASPCSRMo5Tnx38c_J3e8AnnslnY9tHHmnkkjmLkQW57mIey6CNgiaA-U7j97Hw3N5OlGTHXi9yYVp-CHaD27kGfX7mhzcusXRljT0i59VXWJDo7VPX8REnP_2Y8sdhUinJvYm_IAe3Zu03KT8aNv06mz0G8S8iljrKefkFnze3GwTafK1u6xcN_vxC4_j_z7Nbbi5xqLsTWM8d2DHF3fhelOdcnUPvg22zOCspqFlZWCfUHRezqbVHDXKqL7KEo2Z2SJnHy7wJUaRklPLcFG7mrlyYV-xEcX8UfbL6pCN3w0O2fCMttTCUqzl92mOe0YZFlTI4j6cnxyPB8NoXaYhykQi-pHhOlc29AT3cT-zynqpjc2lT2TsDfq_SBznIRM9bk2CFuO0lC6hpagzXuTiAewWZeEfAXOINoXTNgTEaVp5p7lNjAm9gCtXp7MOvNioK83WHOZUSuMibdiXeUrjmNbj2IFnrexlw9zxR6n9jdbTtfcuUoGwGadtpXQHnran0e_oZ4otfLkkGUquFEbFHXjYWEvbDRHsGBPjxV_WOv9L_-np8WhcH-39i_BjuMERXTVRhfuwW82X_gmio8odwDUuzw5qX_gJlr4MdA |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9swELcQE9peNthnB2OetpchUoodxw5vUwUqrGVoFKlvkZ3YUjeaTG060f31u3NCKj40abwkkXKOFdtn_86--x0hn6wIjY10FFgj4iDMjAs0rHMBs4w7qQA0O4x3HpxGvYvwZCRGtW8OxsJU_BDNhhtqhp-vUcFxQ3pvyRr6w07KNtKhgfHzyB_QISb63rBHAdbx1N6IIECnO6OGnZTtLcveXI_ugMybmNUvOkfPqsyqM89ViL4mP9vz0rTTP7eYHB_8P-vkaQ1H6Zdq_GyQFZs_J2tVgsrFC_K7uyQHp56JlhaOnoPotJiMyyl0KsUUK3MYz1TnGf12CfMYOkuONQW7djExxUwf0AG6_WEAzGKXDvvdXdo7wyuW0OhueTXO4E4xyAJzWbwkF0eHw24vqDM1BCmP-X6gmMyEdh3ObLSfaqFtKJXOQhuHkVUwBfDYMOZS3mFaxTBojAxDE6M1apTlGX9FVvMit28INQA4uZHaOYBqUlgjmY6Vch0HxquRaYt8vu6vJK1pzDGbxmVSETCzBNsx8e3YIh8b2V8Vece9UlvX3Z7UCjxLOCBnWLmFkC3yoXkNqofnKTq3xRxlML6SKxG1yOtquDTVIMeOUhF8fMd3-j_qT04OB0P_9PZ_hN-Tx73hoJ_0j0-_bpInDMBW5WS4RVbL6dy-A7BUmm2vEn8BAUYPuw |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3da9swED9Kx8ZexrrPbG2nsb1s1GuiD0sufSlZQ9Y1XWAp5M1ItgQZjV3SZCz_fe_sxKF0DPZiG3yyQHcn_WTd_Q7go1fS-djGkXcqiWTuQmRxnYu45yJog6A5UL7z4CLuX8qzsRpvwfE6F6bmh2h-uJFnVPM1Ofh1Hg43pKG__HT-hdjQcO_zQKLhkX1zOWzOEDo1szcBCHTp9rghJ-WHm7Z3l6N7GPMuZK3WnN5TeLICi-yk1u4ObPniGTysy0cun8Pv7oa6m1U8sawM7CeKzsrpZD7DIWdUAGWB1sZskbMfVzjLUCjjxDLcdS6nrryxR2xAQXmUnrI8YKPz7gHrD-lKLSwFQ_6Z5HhnlAJBlSZewGXvdNTtR6s6ClEmEtGJDNe5sqEtuI87mVXWS21sLn0iY2_QQUXiOA-ZaHNrElSp01K6hPaKzniRi5ewXZSFfw3MIRwUTtsQEEhp5Z3mNjEmtANuLZ3OWvBpPZxptiIZp1oXV2lNj8xTGvq0GvoWfGhkr2tqjb9K7a61kq7c6yYViGtxXVVKt-B98xodg047bOHLBclQ9qMwKm7Bq1qbTTfEgGNMjB__XKn3H_2nZ6eDUfX05n-E38Gj4ddeev7t4vtbeMwRCdURgLuwPZ8t_B4imbnbrwz2FsX_7bs |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Comparative+study+of+Scleromitrion+diffusum+and+Oldenlandia+corymbosa%3A+Microscopy%2C+TLC%2C+HPLC%2C+and+antioxidant+activity&rft.jtitle=Microscopy+research+and+technique&rft.au=Yu%E2%80%90Ling+Ho&rft.au=Thanh%E2%80%90Thuy%E2%80%90Dung+Au&rft.au=Hung%E2%80%90Yi+Wu&rft.au=Kun%E2%80%90Chang+Wu&rft.date=2024-10-01&rft.pub=Wiley+Subscription+Services%2C+Inc&rft.issn=1059-910X&rft.eissn=1097-0029&rft.volume=87&rft.issue=10&rft.spage=2371&rft.epage=2384&rft_id=info:doi/10.1002%2Fjemt.24611&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1059-910X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1059-910X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1059-910X&client=summon |