Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer - Xie, Lin; Jiang, Feng-Chao; Zhang, Li-Min; He, Wen-Tao; Liu, Jian-Hua; Li, Ming-Qiang; Zhang, Xue; Xing, Shuai; Guo, Hui; Zhou, Ping (JNCI : Journal of the National Cancer Institute, 2016)
Keywords: Animals; Antineoplastic Agents - pharmacology; Chemokines - antagonists & inhibitors; Colitis - complications; Colorectal Neoplasms - etiology; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - prevention & control; Cytokines - antagonists & inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy - methods; Myeloid Differentiation Factor 88 - antagonists & inhibitors; Myeloid Differentiation Factor 88 - metabolism; Piperazines - pharmacology; Protein Multimerization - drug effects; Real-Time Polymerase Chain Reaction; Signal Transduction; Thiazoles - pharmacology