Metabonomic study of biochemical changes in urinary of type 2 diabetes mellitus patients after the treatment of sulfonylurea antidiabetic drugs based on ultra-performance liquid chromatography/mass spectrometry - Huo, Taoguang; Xiong, Zhili; Lu, Xiumei; Cai, Shuang (Biomedical chromatography, 2015)
Keywords: Aged; Biomarkers - urine; Chromatography, High Pressure Liquid - methods; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - urine; Humans; Hypoglycemic Agents - administration & dosage; Male; Mass Spectrometry - methods; metabolite profiles; Metabolome - drug effects; Metabolomics; Middle Aged; Multivariate Analysis; Principal Component Analysis; Reproducibility of Results; sulfonylurea; Sulfonylurea Compounds - administration & dosage; type 2 diabetes mellitus; UPLC/MS; UPLC/MS; type 2 diabetes mellitus; sulfonylurea; metabolite profiles