Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron‐induced hepatotoxicity - Xiong, Hui; Zhang, Chunze; Han, Lifeng; Xu, Tong; Saeed, Khawar; Han, Jing; Liu, Jing; Klaassen, Curtis D.; Gonzalez, Frank J.; Lu, Yuanfu; Zhang, Youcai (Hepatology (Baltimore, Md.), 2022)
Keywords: Agonists; Ammonium; Bile; Bile acids; Blood diseases; Dextran; Diet; Fatty liver; Ferrous sulfate; Fibroblast growth factors; Hepatocytes; Hepatology; Hepatotoxicity; Homeostasis; Iron; Iron deficiency; Liver diseases; Metabolic syndrome; Nutrient deficiency; Oral administration; Regulatory proteins; Serum levels; Steatosis; Thalassemia