Temporal pole epilepsy surgery—Sparing the hippocampus

• Published in: Epilepsia (Copenhagen) Vol. 61; no. 10; pp. e146 - e152
• Main Authors: Herlin, Bastien, Adam, Claude, Habert, Marie Odile, Mathon, Bertrand, Clemenceau, Stéphane, Navarro, Vincent, Dupont, Sophie
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.10.2020; Wiley
• Subjects: Adolescent; Adult; Convulsions & seizures; Drug Resistant Epilepsy - diagnostic imaging; Drug Resistant Epilepsy - surgery; Epilepsy; Epilepsy, Temporal Lobe - diagnostic imaging; Epilepsy, Temporal Lobe - surgery; Female; Hippocampus - diagnostic imaging; Humans; Life Sciences; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Middle Aged; Neurons and Cognition; Seizures; Surgery; Temporal lobe; Temporal Lobe - diagnostic imaging; Temporal Lobe - surgery; Young Adult
• ISSN: 0013-9580; 1528-1167; 1528-1167
• DOI: 10.1111/epi.16693

Temporal pole epilepsy (TPE) is a poorly known and difficult to individualize subtype of temporal lobe epilepsy. Consequently, in drug‐resistant TPE, there is still a debate on the need for a large surgical removal of the temporal pole and mesial temporal structures or a limited resection of the temporal pole. We reviewed all patients who underwent presurgical evaluation for drug‐resistant epilepsy over a 17‐year period, and report here 19 patients with proven drug‐resistant temporal pole epilepsy who underwent a selective temporal pole resection with respect to mesial structures. Most (15) TPE patients exhibited seizures resembling mesiotemporal seizures, whereas the others exhibited nocturnal hyperkinetic seizures or an association of both seizure types. MRI revealed a temporal pole lesion in 58% of patients. Long‐term postoperative outcome after a conservative surgery was excellent: 63% of patients were seizure‐free (International League Against Epilepsy [ILAE] 1) at 1‐year postsurgery and 78% at 5 years. These results show that TPE has no specific electroclinical features but is a distinct type of temporal lobe epilepsy allowing a conservative surgery. Respecting the mesiotemporal structures is a valid surgical approach for drug‐resistant temporal pole epilepsy.