Marrow infarction in sickle cell anemia: Correlation with marrow type and distribution by MRI
Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlat...
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| Published in | Magnetic resonance imaging Vol. 7; no. 1; pp. 39 - 44 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York, NY
Elsevier Inc
1989
Elsevier Science |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0730-725X 1873-5894 |
| DOI | 10.1016/0730-725X(89)90322-6 |
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| Abstract | Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlate the distribution and appearance of marrow infarction with the type of marrow. While the hematopoietic marrow predominated in metaphyseal and diaphyseal regions of femurs and tibias, the fatty or mixed marrow was the most common pattern in epiphyses. Infarcts occurred in fatty as well as hematopoietic marrow. Marrow infarcts were isointense or minimally hyperintense on
T
1 weighted images with the hematopoietic marrow and therefore difficult to detect. On
T
2 weighted images, the infarcts showed very high signal.
T
2 weighted images are essential for detection of marrow infarction. Soft tissue changes seen as low signal on
T
1 and high signal on
T
2, may be secondary to intramuscular injections of analgesics or muscle ischemicia occurring during sickle crisis. |
|---|---|
| AbstractList | Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlate the distribution and appearance of marrow infarction with the type of marrow. While the hematopoietic marrow predominated in metaphyseal and diaphyseal regions of femurs and tibias, the fatty or mixed marrow was the most common pattern in epiphyses. Infarcts occurred in fatty as well as hematopoietic marrow. Marrow infarcts were isointense or minimally hyperintense on T1 weighted images with the hematopoietic marrow and therefore difficult to detect. On T2 weighted images, the infarcts showed very high signal. T2 weighted images are essential for detection of marrow infarction. Soft tissue changes seen as low signal on T1 and high signal on T2, may be secondary to intramuscular injections of analgesics or muscle ischemia occurring during sickle crisis. Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlate the distribution and appearance of marrow infarction with the type of marrow. While the hematopoietic marrow predominated in metaphyseal and diaphyseal regions of femurs and tibias, the fatty or mixed marrow was the most common pattern in epiphyses. Infarcts occurred in fatty as well as hematopoietic marrow. Marrow infarcts were isointense or minimally hyperintense on T1 weighted images with the hematopoietic marrow and therefore difficult to detect. On T2 weighted images, the infarcts showed very high signal. T2 weighted images are essential for detection of marrow infarction. Soft tissue changes seen as low signal on T1 and high signal on T2, may be secondary to intramuscular injections of analgesics or muscle ischemia occurring during sickle crisis.Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlate the distribution and appearance of marrow infarction with the type of marrow. While the hematopoietic marrow predominated in metaphyseal and diaphyseal regions of femurs and tibias, the fatty or mixed marrow was the most common pattern in epiphyses. Infarcts occurred in fatty as well as hematopoietic marrow. Marrow infarcts were isointense or minimally hyperintense on T1 weighted images with the hematopoietic marrow and therefore difficult to detect. On T2 weighted images, the infarcts showed very high signal. T2 weighted images are essential for detection of marrow infarction. Soft tissue changes seen as low signal on T1 and high signal on T2, may be secondary to intramuscular injections of analgesics or muscle ischemia occurring during sickle crisis. Ischemic necrosis of bone is believed to occur exclusively in areas of predominantly fatty marrow. Sickle cell disease is unusual in that marrow infarction occurs in areas of active hematopoiesis. MR images of long bone obtained in ten patients with sickle cell anemia (SCA) were analyzed to correlate the distribution and appearance of marrow infarction with the type of marrow. While the hematopoietic marrow predominated in metaphyseal and diaphyseal regions of femurs and tibias, the fatty or mixed marrow was the most common pattern in epiphyses. Infarcts occurred in fatty as well as hematopoietic marrow. Marrow infarcts were isointense or minimally hyperintense on T 1 weighted images with the hematopoietic marrow and therefore difficult to detect. On T 2 weighted images, the infarcts showed very high signal. T 2 weighted images are essential for detection of marrow infarction. Soft tissue changes seen as low signal on T 1 and high signal on T 2, may be secondary to intramuscular injections of analgesics or muscle ischemicia occurring during sickle crisis. |
| Author | Rifkin, Matthew D. Rao, Vijay M. Levy, David Burk, D.Lawrence Mitchell, Donald G. Steiner, Robert M. Ballas, Samir K. |
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| Cites_doi | 10.1148/radiology.162.3.3809484 10.1148/radiology.166.1.3336680 10.2214/ajr.143.6.1273 10.1016/S0033-8389(22)01074-0 10.1016/0730-725X(88)90090-2 10.1016/0730-725X(85)90350-9 10.1097/00003086-198605000-00016 10.1007/BF00350542 10.2214/ajr.146.2.353 10.1148/radiology.161.1.3763869 10.1016/S0033-8389(22)01076-4 |
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| Keywords | SCA Marrow infarction Bone infarction Bone marrow Hemoglobinopathy Hemopathy Sickle cell anemia Infarct Nuclear magnetic resonance imaging |
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| References | Sweet, Madewell (BIB9) 1981 Berquist, Brown, Fitzgerald, May (BIB15) 1985; 3 (in press). Huber, Sumers, Klein (BIB16) 1987; 16 Powers (BIB2) 1986; 206 Mitchell, Rao, Dalinka (BIB6) 1987; 162 Mitchell, Kundal, Steinberg, Kressel, Alavi, Axel (BIB7) 1984; 143 Porter, Shields, Olson (BIB1) 1986; 24 Bohrer (BIB10) 1981 Tang, Gold, Bassett, Seeger (BIB13) 1988; 166 Rao, Fishman, Mitchell (BIB3) 1986; 161 Totty, Murphy, Ganz, Kumar, Daum, Siegel (BIB5) 1984; 143 Modic, Pflanze, Feiglin, Belhobek (BIB14) 1986; 24 Moore, Gooding, Ehman (BIB8) August 1985 Bohrer (BIB11) 1987; 22 Rao, V.M., Mitchell, D.G., Steiner, R.M., Rifkin, M.D., Levy, D., Ballas, S. Femoral head avascular necrosis in sickle cell anemia: MRI characteristics. Daffner, Lupetin, Dash, Deeb, Sefczek, Shapiro (BIB4) 1986; 146 Bohrer (10.1016/0730-725X(89)90322-6_BIB11) 1987; 22 Tang (10.1016/0730-725X(89)90322-6_BIB13) 1988; 166 Totty (10.1016/0730-725X(89)90322-6_BIB5) 1984; 143 Bohrer (10.1016/0730-725X(89)90322-6_BIB10) 1981 Powers (10.1016/0730-725X(89)90322-6_BIB2) 1986; 206 Rao (10.1016/0730-725X(89)90322-6_BIB3) 1986; 161 Mitchell (10.1016/0730-725X(89)90322-6_BIB6) 1987; 162 Moore (10.1016/0730-725X(89)90322-6_BIB8) 1985 Modic (10.1016/0730-725X(89)90322-6_BIB14) 1986; 24 Sweet (10.1016/0730-725X(89)90322-6_BIB9) 1981 Berquist (10.1016/0730-725X(89)90322-6_BIB15) 1985; 3 10.1016/0730-725X(89)90322-6_BIB12 Porter (10.1016/0730-725X(89)90322-6_BIB1) 1986; 24 Mitchell (10.1016/0730-725X(89)90322-6_BIB7) 1984; 143 Daffner (10.1016/0730-725X(89)90322-6_BIB4) 1986; 146 Huber (10.1016/0730-725X(89)90322-6_BIB16) 1987; 16 |
| References_xml | – volume: 161 start-page: 211 year: 1986 end-page: 215 ident: BIB3 article-title: Painful sickle cell crisis: Bone marrow patterns observed with MR imaging publication-title: Radiology – year: 1981 ident: BIB10 publication-title: Bone Ischemia and Infarction in Sickle Cell Disease – start-page: 2780 year: 1981 end-page: 2831 ident: BIB9 article-title: Pathogenesis of osteonecrosis publication-title: Diagnosis of Bone and Joint Disorders – reference: (in press). – volume: 143 start-page: 1273 year: 1984 end-page: 1280 ident: BIB5 article-title: Magnetic resonance imaging of the normal and ischemic femoral head publication-title: AJR – volume: 24 start-page: 247 year: 1986 end-page: 258 ident: BIB14 article-title: Magnetic resonance imaging of musculoskeletal infections publication-title: Radiol. Clin. North Am. – volume: 3 start-page: 219 year: 1985 end-page: 230 ident: BIB15 article-title: Magnetic resonance imaging: Application in musculoskeletal infection publication-title: Magn. Reson. Imaging – volume: 16 start-page: 469 year: 1987 end-page: 473 ident: BIB16 article-title: Soft tissue pseudotumor following intramuscular injection of “DPT”: A pitfall in magnetic resonance imaging publication-title: Skeletal Radiol. – volume: 24 start-page: 269 year: 1986 end-page: 289 ident: BIB1 article-title: Magnetic imaging of bone marrow disorders publication-title: Radiol. Clin. North Am. – year: August 1985 ident: BIB8 article-title: Intensity measurements of marrow in patients with acute lymphocyte leukemia publication-title: Presented at the Annual Meeting of the Society of Magnetic Resonance in Medicine – volume: 162 start-page: 709 year: 1987 end-page: 715 ident: BIB6 article-title: Femoral head avascular necrosis: Correlation of MR imaging. Radiographic staging; radionuclide imaging; and clinical findings publication-title: Radiology – reference: Rao, V.M., Mitchell, D.G., Steiner, R.M., Rifkin, M.D., Levy, D., Ballas, S. Femoral head avascular necrosis in sickle cell anemia: MRI characteristics. – volume: 22 start-page: 176 year: 1987 end-page: 185 ident: BIB11 article-title: Bone changes in the extremities in sickle cell anemia publication-title: Seminar Roentgen – volume: 166 start-page: 205 year: 1988 end-page: 209 ident: BIB13 article-title: Musculoskeletal infection of the extremities: Evaluation with MR imaging publication-title: Radiology – volume: 143 start-page: 1273 year: 1984 end-page: 1280 ident: BIB7 article-title: Avascular necrosis of the hip: Comparison of MR, CT and scintigraphy publication-title: AJR – volume: 206 start-page: 79 year: 1986 end-page: 85 ident: BIB2 article-title: Magnetic resonance imaging in marrow diseases publication-title: Clin. Orthop. – volume: 146 start-page: 353 year: 1986 end-page: 358 ident: BIB4 article-title: MRI in detection of malignant infiltration of bone marrow publication-title: AJR – volume: 162 start-page: 709 year: 1987 ident: 10.1016/0730-725X(89)90322-6_BIB6 article-title: Femoral head avascular necrosis: Correlation of MR imaging. Radiographic staging; radionuclide imaging; and clinical findings publication-title: Radiology doi: 10.1148/radiology.162.3.3809484 – volume: 166 start-page: 205 year: 1988 ident: 10.1016/0730-725X(89)90322-6_BIB13 article-title: Musculoskeletal infection of the extremities: Evaluation with MR imaging publication-title: Radiology doi: 10.1148/radiology.166.1.3336680 – volume: 143 start-page: 1273 year: 1984 ident: 10.1016/0730-725X(89)90322-6_BIB5 article-title: Magnetic resonance imaging of the normal and ischemic femoral head publication-title: AJR doi: 10.2214/ajr.143.6.1273 – start-page: 2780 year: 1981 ident: 10.1016/0730-725X(89)90322-6_BIB9 article-title: Pathogenesis of osteonecrosis – volume: 24 start-page: 247 year: 1986 ident: 10.1016/0730-725X(89)90322-6_BIB14 article-title: Magnetic resonance imaging of musculoskeletal infections publication-title: Radiol. Clin. North Am. doi: 10.1016/S0033-8389(22)01074-0 – volume: 22 start-page: 176 year: 1987 ident: 10.1016/0730-725X(89)90322-6_BIB11 article-title: Bone changes in the extremities in sickle cell anemia – year: 1981 ident: 10.1016/0730-725X(89)90322-6_BIB10 – volume: 143 start-page: 1273 year: 1984 ident: 10.1016/0730-725X(89)90322-6_BIB7 article-title: Avascular necrosis of the hip: Comparison of MR, CT and scintigraphy publication-title: AJR – ident: 10.1016/0730-725X(89)90322-6_BIB12 doi: 10.1016/0730-725X(88)90090-2 – volume: 3 start-page: 219 year: 1985 ident: 10.1016/0730-725X(89)90322-6_BIB15 article-title: Magnetic resonance imaging: Application in musculoskeletal infection publication-title: Magn. Reson. Imaging doi: 10.1016/0730-725X(85)90350-9 – volume: 206 start-page: 79 year: 1986 ident: 10.1016/0730-725X(89)90322-6_BIB2 article-title: Magnetic resonance imaging in marrow diseases publication-title: Clin. Orthop. doi: 10.1097/00003086-198605000-00016 – year: 1985 ident: 10.1016/0730-725X(89)90322-6_BIB8 article-title: Intensity measurements of marrow in patients with acute lymphocyte leukemia – volume: 16 start-page: 469 year: 1987 ident: 10.1016/0730-725X(89)90322-6_BIB16 article-title: Soft tissue pseudotumor following intramuscular injection of “DPT”: A pitfall in magnetic resonance imaging publication-title: Skeletal Radiol. doi: 10.1007/BF00350542 – volume: 146 start-page: 353 year: 1986 ident: 10.1016/0730-725X(89)90322-6_BIB4 article-title: MRI in detection of malignant infiltration of bone marrow publication-title: AJR doi: 10.2214/ajr.146.2.353 – volume: 161 start-page: 211 year: 1986 ident: 10.1016/0730-725X(89)90322-6_BIB3 article-title: Painful sickle cell crisis: Bone marrow patterns observed with MR imaging publication-title: Radiology doi: 10.1148/radiology.161.1.3763869 – volume: 24 start-page: 269 year: 1986 ident: 10.1016/0730-725X(89)90322-6_BIB1 article-title: Magnetic imaging of bone marrow disorders publication-title: Radiol. Clin. North Am. doi: 10.1016/S0033-8389(22)01076-4 |
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| SubjectTerms | Adult Anemia, Sickle Cell - pathology Anemias. Hemoglobinopathies Biological and medical sciences Bone and Bones - pathology Bone infarction Bone Marrow - blood supply Diseases of red blood cells Female Hematologic and hematopoietic diseases Humans Infarction - diagnosis Magnetic Resonance Imaging Male Marrow infarction Medical sciences SCA |
| Title | Marrow infarction in sickle cell anemia: Correlation with marrow type and distribution by MRI |
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