Understanding the Mechanism of Bacterial Biofilms Resistance to Antimicrobial Agents

A biofilm is a group of microorganisms, that causes health problems for the patients with indwelling medical devices via attachment of cells to the surface matrix. It increases the resistance of a microorganism for antimicrobial agents and developed the human infection. Current strategies are remove...

Full description

Saved in:
Bibliographic Details
Published inThe open microbiology journal Vol. 11; no. 1; pp. 53 - 62
Main Authors Singh, Shriti, Singh, Santosh Kumar, Chowdhury, Indrajit, Singh, Rajesh
Format Journal Article
LanguageEnglish
Published United Arab Emirates Bentham Open 28.04.2017
Subjects
Resistance
Biofilm
Heterogeneity
Quorum sensing
Efflux pump
Online AccessGet full text
ISSN1874-2858
1874-2858
DOI10.2174/1874285801711010053

Cover

More Information
Summary:A biofilm is a group of microorganisms, that causes health problems for the patients with indwelling medical devices via attachment of cells to the surface matrix. It increases the resistance of a microorganism for antimicrobial agents and developed the human infection. Current strategies are removed or prevent the microbial colonies from the medical devices, which are attached to the surfaces. This will improve the clinical outcomes in favor of the patients suffering from serious infectious diseases. Moreover, the identification and inhibition of genes, which have the major role in biofilm formation, could be the effective approach for health care systems. In a current review article, we are highlighting the biofilm matrix and molecular mechanism of antimicrobial resistance in bacterial biofilms.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1874-2858
1874-2858
DOI:10.2174/1874285801711010053