Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening - Hernández-Abreu, Oswaldo; Castillo-España, Patricia; León-Rivera, Ismael; Ibarra-Barajas, Maximiliano; Villalobos-Molina, Rafael; González-Christen, Judith; Vergara-Galicia, Jorge; Estrada-Soto, Samuel (Biochemical pharmacology, 2009)
Keywords: Agastache - chemistry; Agastache mexicana; Antihypertensive; Antihypertensive Agents - therapeutic use; Biological and medical sciences; cGMP; Cyclic GMP - physiology; Dose-Response Relationship, Drug; Flavonoids - isolation & purification; Flavonoids - therapeutic use; Glycosides - isolation & purification; Glycosides - therapeutic use; Humans; Ion Channel Gating - drug effects; Medical sciences; Medicine, Traditional; Methanol; Mexico; Nitric oxide; Nitric Oxide - physiology; Pharmacology. Drug treatments; Plant Extracts - isolation & purification; Plant Extracts - pharmacology; Plants, Medicinal; Potassium Channels - drug effects; Potassium Channels - physiology; Tilianin; Vasodilator Agents - therapeutic use; Mexico; Antihypertensive; cGMP; Tilianin; Nitric oxide; Agastache mexicana; Vasodilator agent; Pharmacognosy; 3',5'-GMP; Ionic channel; Inorganic element; In vitro; Medicinal plant; Labiatae; Opening; Dicotyledones; Angiospermae; Antihypertensive agent; Spermatophyta; Potassium