Effect of Radiotherapy Alone vs Radiotherapy With Concurrent Chemoradiotherapy on Survival Without Disease Relapse in Patients With Low-risk Nasopharyngeal Carcinoma: A Randomized Clinical Trial - Tang, Ling-Long; Guo, Rui; Zhang, Ning; Deng, Bin; Chen, Lei; Cheng, Zhi-Bin; Huang, Jing; Hu, Wei-Han; Huang, Shao Hui; Luo, Wei-Jun; Liang, Jin-Hui; Zheng, Yu-Ming; et al. (JAMA : the journal of the American Medical Association, 2022)
Keywords: Adult; Adverse events; Anorexia; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Appetite loss; Body weight loss; Cancer; Chemoradiotherapy; Chemoradiotherapy - adverse effects; Chemoradiotherapy - methods; Chemotherapy; Cisplatin; Cisplatin - administration & dosage; Cisplatin - adverse effects; Clinical trials; Constipation; DNA viruses; Epstein-Barr virus; Epstein-Barr Virus Infections - complications; Female; Global health; Health services; Herpesvirus 4, Human; Humans; Insomnia; Leukopenia; Male; Metastases; Metastasis; Middle Aged; Mucositis; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - drug therapy; Nasopharyngeal Carcinoma - etiology; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Carcinoma - radiotherapy; Nasopharyngeal Neoplasms - drug therapy; Nasopharyngeal Neoplasms - etiology; Nasopharyngeal Neoplasms - pathology; Nasopharyngeal Neoplasms - radiotherapy; Nausea; Neutropenia; Nodes; Original Investigation; Pain; Patients; Public health; Quality of Life; Radiation; Radiation therapy; Radiotherapy, Intensity-Modulated - adverse effects; Radiotherapy, Intensity-Modulated - methods; Randomization; Risk; Signs and symptoms; Sleep disorders; Survival; Throat cancer; Toxicity; Vomiting; Weight loss