The unrecognized prevalence of chronic kidney disease in diabetes
Background. Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this s...
Saved in:
Published in | Nephrology, dialysis, transplantation Vol. 21; no. 1; pp. 88 - 92 |
---|---|
Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Oxford University Press
01.01.2006
Oxford Publishing Limited (England) |
Subjects | |
Online Access | Get full text |
ISSN | 0931-0509 1460-2385 |
DOI | 10.1093/ndt/gfi163 |
Cover
Abstract | Background. Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods. All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR <60 ml/min/1.73 m2. Results. Creatinine and albuminuria were measured in the preceding 2 years in 82.3 and 55.2% of subjects, respectively. In patients with CKD, normoalbuminuria was present in 48.8%, and serum creatinine was normal (≤120 µmol/l) in 54.7%. An abnormal serum creatinine (≥120 µmol/l) had a sensitivity and specificity of 45.3 and 100%, respectively, to identify CKD. The combination of abnormal creatinine and albuminuria had an improved performance but still failed to detect a large number with CKD (sensitivity 82.4%, specificity 75.4%). Serum creatinine failed to identify CKD more often in females (OR 8.22, CI 6.56–10.29). Conclusions. Undiagnosed CKD is common in diabetes. Current screening strategies, based on creatinine or albuminuria, fail to identify a considerable number of subjects with CKD. Incorporating eGFR into screening for CKD would identify individuals earlier in the natural history of the disease and enable early effective treatment to delay progression of CKD. |
---|---|
AbstractList | Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR).
All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n=7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR <60 ml/min/1.73 m(2).
Creatinine and albuminuria were measured in the preceding 2 years in 82.3 and 55.2% of subjects, respectively. In patients with CKD, normoalbuminuria was present in 48.8%, and serum creatinine was normal (<or=120 micromol/l) in 54.7%. An abnormal serum creatinine (>or=120 micromol/l) had a sensitivity and specificity of 45.3 and 100%, respectively, to identify CKD. The combination of abnormal creatinine and albuminuria had an improved performance but still failed to detect a large number with CKD (sensitivity 82.4%, specificity 75.4%). Serum creatinine failed to identify CKD more often in females (OR 8.22, CI 6.56-10.29).
Undiagnosed CKD is common in diabetes. Current screening strategies, based on creatinine or albuminuria, fail to identify a considerable number of subjects with CKD. Incorporating eGFR into screening for CKD would identify individuals earlier in the natural history of the disease and enable early effective treatment to delay progression of CKD. Background. Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR). Methods. All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n = 7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR <60 ml/min/1.73 m2. Results. Creatinine and albuminuria were measured in the preceding 2 years in 82.3 and 55.2% of subjects, respectively. In patients with CKD, normoalbuminuria was present in 48.8%, and serum creatinine was normal (≤120 µmol/l) in 54.7%. An abnormal serum creatinine (≥120 µmol/l) had a sensitivity and specificity of 45.3 and 100%, respectively, to identify CKD. The combination of abnormal creatinine and albuminuria had an improved performance but still failed to detect a large number with CKD (sensitivity 82.4%, specificity 75.4%). Serum creatinine failed to identify CKD more often in females (OR 8.22, CI 6.56-10.29). Conclusions. Undiagnosed CKD is common in diabetes. Current screening strategies, based on creatinine or albuminuria, fail to identify a considerable number of subjects with CKD. Incorporating eGFR into screening for CKD would identify individuals earlier in the natural history of the disease and enable early effective treatment to delay progression of CKD. Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR).BACKGROUNDDiabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the UK recommend annual urinary albumin and serum creatinine determinations to screen for diabetic kidney disease. The aim of this study was to estimate the burden of CKD in patients with diabetes and examine the ability of serum creatinine and albuminuria to detect clinically meaningful CKD compared with estimated glomerular filtration rate (eGFR).All adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n=7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR <60 ml/min/1.73 m(2).METHODSAll adults known to have diabetes in primary and secondary care in Salford, UK, alive with independent renal function on 1 January 2004 were included in this observational study (n=7596). Demographic and laboratory parameters were obtained from the Electronic Patient Record. eGFR was determined using the 4-variable modification of diet in renal disease (MDRD) formula. Clinically meaningful CKD was defined as an eGFR <60 ml/min/1.73 m(2).Creatinine and albuminuria were measured in the preceding 2 years in 82.3 and 55.2% of subjects, respectively. In patients with CKD, normoalbuminuria was present in 48.8%, and serum creatinine was normal (<or=120 micromol/l) in 54.7%. An abnormal serum creatinine (>or=120 micromol/l) had a sensitivity and specificity of 45.3 and 100%, respectively, to identify CKD. The combination of abnormal creatinine and albuminuria had an improved performance but still failed to detect a large number with CKD (sensitivity 82.4%, specificity 75.4%). Serum creatinine failed to identify CKD more often in females (OR 8.22, CI 6.56-10.29).RESULTSCreatinine and albuminuria were measured in the preceding 2 years in 82.3 and 55.2% of subjects, respectively. In patients with CKD, normoalbuminuria was present in 48.8%, and serum creatinine was normal (<or=120 micromol/l) in 54.7%. An abnormal serum creatinine (>or=120 micromol/l) had a sensitivity and specificity of 45.3 and 100%, respectively, to identify CKD. The combination of abnormal creatinine and albuminuria had an improved performance but still failed to detect a large number with CKD (sensitivity 82.4%, specificity 75.4%). Serum creatinine failed to identify CKD more often in females (OR 8.22, CI 6.56-10.29).Undiagnosed CKD is common in diabetes. Current screening strategies, based on creatinine or albuminuria, fail to identify a considerable number of subjects with CKD. Incorporating eGFR into screening for CKD would identify individuals earlier in the natural history of the disease and enable early effective treatment to delay progression of CKD.CONCLUSIONSUndiagnosed CKD is common in diabetes. Current screening strategies, based on creatinine or albuminuria, fail to identify a considerable number of subjects with CKD. Incorporating eGFR into screening for CKD would identify individuals earlier in the natural history of the disease and enable early effective treatment to delay progression of CKD. |
Author | McElduff, Patrick Foley, Robert N. O'Donoghue, Donal J. Hegarty, Janet Kalra, Philip A. New, John P. Middleton, Rachel J. Gibson, J. Martin Cheung, Ching M. |
Author_xml | – sequence: 1 givenname: Rachel J. surname: Middleton fullname: Middleton, Rachel J. organization: Department of Renal Medicine, Hope Hospital, Salford, UK – sequence: 2 givenname: Robert N. surname: Foley fullname: Foley, Robert N. organization: Chronic Disease Research Group and University of Minnesota, USA – sequence: 3 givenname: Janet surname: Hegarty fullname: Hegarty, Janet organization: Department of Renal Medicine, Hope Hospital, Salford, UK – sequence: 4 givenname: Ching M. surname: Cheung fullname: Cheung, Ching M. organization: Department of Renal Medicine, Hope Hospital, Salford, UK – sequence: 5 givenname: Patrick surname: McElduff fullname: McElduff, Patrick organization: Evidence of Public Health Unit, School of Epidemiology and Health Sciences, University of Manchester, UK and – sequence: 6 givenname: J. Martin surname: Gibson fullname: Gibson, J. Martin organization: Department of Diabetes and Endocrinology, Hope Hospital, Salford, UK – sequence: 7 givenname: Philip A. surname: Kalra fullname: Kalra, Philip A. organization: Department of Renal Medicine, Hope Hospital, Salford, UK – sequence: 8 givenname: Donal J. surname: O'Donoghue fullname: O'Donoghue, Donal J. organization: Department of Renal Medicine, Hope Hospital, Salford, UK – sequence: 9 givenname: John P. surname: New fullname: New, John P. organization: Department of Diabetes and Endocrinology, Hope Hospital, Salford, UK |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17447493$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/16221715$$D View this record in MEDLINE/PubMed |
BookMark | eNpt0UFLHDEUB_BQLHW1vfQDlKFgD4XRZDKTTI6ytCoqveyheAlvkheNzibbZKbUfvqm7FZBekogv_d4L_8DshdiQELeM3rMqOInwU4nt84zwV-RBWsFrRved3tkUR5ZTTuq9slBzveUUtVI-YbsM9E0TLJuQU5Xd1jNIaGJt8H_RlttEv6EEYPBKrrK3KUYvKkevA34WFmfETJWPpQrDDhhfkteOxgzvtudh2T19ctqeV5ffTu7WJ5e1Yb3dKq7tufMAO-lZRKGoWW8AdoZjsrKRg28Ey0zSolhAAFODs4q5wy1EsuwwA_Jp23bTYo_ZsyTXvtscBwhYJyzFrJTvWxEgR9fwPs4p1BG0w3rWUuZkAV92KF5WKPVm-TXkB71v48p4GgHIBsYXYJgfH52sm1lq3hxn7fOpJhzQvdMqP6bji7p6G06BdMX2PgJJh_DlMCP_y-ptyU-T_jrqTmkh7Ixl50-_36jz_g1X95cXmrJ_wCK6qFl |
CODEN | NDTREA |
CitedBy_id | crossref_primary_10_1111_j_1464_5491_2007_02023_x crossref_primary_10_1136_bmj_l1516 crossref_primary_10_1152_ajprenal_00507_2009 crossref_primary_10_2337_dc13_2855 crossref_primary_10_1080_14737167_2019_1650024 crossref_primary_10_1186_s12882_019_1309_y crossref_primary_10_2337_diaclin_25_3_90 crossref_primary_10_1038_hr_2014_9 crossref_primary_10_1186_s12882_020_01768_y crossref_primary_10_1186_s12933_015_0204_5 crossref_primary_10_1016_j_jdiacomp_2007_08_001 crossref_primary_10_1155_2012_749812 crossref_primary_10_1016_j_diabres_2011_05_032 crossref_primary_10_34172_aim_31194 crossref_primary_10_2337_dc07_0140 crossref_primary_10_1093_ndt_gfv093 crossref_primary_10_1186_1471_2369_10_25 crossref_primary_10_1016_j_diabet_2008_03_004 crossref_primary_10_1016_j_clinthera_2016_07_006 crossref_primary_10_1016_j_diabet_2012_08_004 crossref_primary_10_3810_pgm_2011_05_2289 crossref_primary_10_1016_j_jsps_2013_08_004 crossref_primary_10_1016_S0025_7753_08_72242_5 crossref_primary_10_1016_j_ekir_2024_04_005 crossref_primary_10_1038_s41598_021_84464_7 crossref_primary_10_1149_2_018206jes crossref_primary_10_5551_jat_16261 crossref_primary_10_1016_j_diabet_2011_05_002 crossref_primary_10_1016_j_jcjd_2017_11_004 crossref_primary_10_1186_s12882_024_03764_y crossref_primary_10_1111_j_1464_5491_2006_01954_x crossref_primary_10_1111_j_1532_5415_2007_01196_x crossref_primary_10_1002_dmrr_2793 crossref_primary_10_1111_dom_12630 crossref_primary_10_1016_j_nephro_2011_07_410 crossref_primary_10_1016_j_jdiacomp_2023_108403 crossref_primary_10_1080_22201009_2012_10872277 crossref_primary_10_1016_j_pcd_2014_05_001 crossref_primary_10_1007_s00125_007_0796_8 crossref_primary_10_1111_bcp_15484 crossref_primary_10_1186_1471_2369_13_87 crossref_primary_10_1111_rssa_12682 crossref_primary_10_1016_S1885_5857_09_73531_5 crossref_primary_10_3390_jcm4071348 crossref_primary_10_1001_jamanetworkopen_2018_7896 crossref_primary_10_1371_journal_pone_0194330 crossref_primary_10_1093_ndt_gfp579 crossref_primary_10_4065_83_12_1373 crossref_primary_10_1371_journal_pone_0055580 crossref_primary_10_1016_j_dsx_2017_11_002 crossref_primary_10_1080_22201009_2012_10872287 crossref_primary_10_1186_1471_2369_14_198 crossref_primary_10_1111_j_1464_5491_2006_01995_x crossref_primary_10_1517_17425255_2012_658771 crossref_primary_10_1016_j_ijcard_2017_01_038 crossref_primary_10_1007_s40262_017_0528_2 crossref_primary_10_15829_1728_8800_2024_3996 crossref_primary_10_1590_S0004_27302010000300002 crossref_primary_10_1016_j_jcjd_2015_09_089 crossref_primary_10_1002_pdi_881 crossref_primary_10_2337_db08_0866 crossref_primary_10_1097_MAJ_0b013e318181288e crossref_primary_10_1093_bmb_lds030 crossref_primary_10_3892_mco_2018_1554 crossref_primary_10_1111_j_1440_1797_2006_00709_x crossref_primary_10_1007_s12325_015_0261_x crossref_primary_10_1109_ACCESS_2025_3535692 crossref_primary_10_1186_1471_2369_15_86 crossref_primary_10_3390_ijms241713636 crossref_primary_10_1007_s40262_013_0113_2 crossref_primary_10_5582_bst_2017_01104 crossref_primary_10_1080_13543784_2019_1592156 crossref_primary_10_1093_ndt_gfn692 crossref_primary_10_1007_s00508_013_0374_7 crossref_primary_10_1016_j_cegh_2024_101641 crossref_primary_10_1210_clinem_dgaa894 crossref_primary_10_1517_14656566_8_15_2543 crossref_primary_10_1007_s40264_014_0247_7 crossref_primary_10_1007_s40200_020_00680_4 crossref_primary_10_1016_j_jcjd_2014_07_221 crossref_primary_10_1016_S2211_9477_12_70008_0 crossref_primary_10_1016_S0300_8932_09_73122_7 crossref_primary_10_1016_j_jcjd_2013_01_037 crossref_primary_10_1016_j_ejcdt_2016_09_002 crossref_primary_10_1093_ndt_gfl180 crossref_primary_10_13005_bbra_2618 crossref_primary_10_1016_j_nephro_2010_04_006 crossref_primary_10_1093_ndt_gfl181 crossref_primary_10_1038_nrneph_2010_84 crossref_primary_10_1016_S0828_282X_07_70806_1 crossref_primary_10_1378_chest_09_1710 crossref_primary_10_3803_EnM_2016_31_4_533 crossref_primary_10_1002_14651858_CD007374_pub2 crossref_primary_10_1002_14651858_CD007374_pub3 crossref_primary_10_1016_j_refiri_2017_03_003 crossref_primary_10_11124_JBISRIR_2016_003011 crossref_primary_10_1007_s40620_018_00563_1 crossref_primary_10_1007_s10792_022_02332_3 crossref_primary_10_1093_ndt_gfv073 crossref_primary_10_1055_s_0040_1721665 crossref_primary_10_1093_qjmed_hct182 crossref_primary_10_2215_CJN_00780110 crossref_primary_10_1186_1471_2369_15_198 crossref_primary_10_3389_fendo_2024_1324782 crossref_primary_10_1093_ndt_gfx375 crossref_primary_10_1016_j_jcjd_2013_07_026 crossref_primary_10_3109_0886022X_2011_615969 crossref_primary_10_1002_14651858_CD006800_pub2 crossref_primary_10_2215_CJN_04080320 |
Cites_doi | 10.1093/clinchem/38.10.1933 10.2337/diacare.27.2007.S15 10.1681/ASN.2004070539 10.1681/ASN.2004060447 10.1056/NEJMoa041031 10.2337/diacare.26.6.1806 10.1093/ndt/17.7.1252 10.1681/ASN.V7122627 10.2337/diacare.28.4.838 10.1046/j.1523-1755.2003.00712.x 10.1016/S0140-6736(98)07368-1 10.1177/14746514020020041401 10.2337/diacare.27.5.1047 10.1046/j.1523-1755.64.s87.5.x 10.1053/ajkd.2003.50007 10.1016/j.ajkd.2003.07.006 |
ContentType | Journal Article |
Copyright | 2006 INIST-CNRS Copyright Oxford University Press(England) Jan 20, 2006 |
Copyright_xml | – notice: 2006 INIST-CNRS – notice: Copyright Oxford University Press(England) Jan 20, 2006 |
DBID | BSCLL AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7QP 7T5 H94 K9. 7X8 |
DOI | 10.1093/ndt/gfi163 |
DatabaseName | Istex CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Calcium & Calcified Tissue Abstracts Immunology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Immunology Abstracts Calcium & Calcified Tissue Abstracts MEDLINE - Academic |
DatabaseTitleList | MEDLINE AIDS and Cancer Research Abstracts MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1460-2385 |
EndPage | 92 |
ExternalDocumentID | 958471671 16221715 17447493 10_1093_ndt_gfi163 ark_67375_HXZ_G3M3CZKK_7 |
Genre | Journal Article Comparative Study |
GroupedDBID | --- -E4 .2P .55 .GJ .I3 .XZ .ZR 0R~ 123 18M 1TH 29M 2WC 4.4 482 48X 53G 5RE 5VS 5WA 5WD 70D AABZA AACZT AAHTB AAJKP AAJQQ AAMDB AAMVS AAOGV AAPGJ AAPNW AAPQZ AAPXW AARHZ AAUAY AAUQX AAVAP AAWDT ABDFA ABEJV ABEUO ABGNP ABIXL ABKDP ABNGD ABNHQ ABNKS ABOCM ABPEJ ABPQP ABPTD ABQLI ABQNK ABSMQ ABVGC ABWST ABXVV ABZBJ ACFRR ACGFO ACGFS ACPQN ACPRK ACUFI ACUKT ACUTJ ACUTO ACVCV ACYHN ACZBC ADBBV ADEYI ADEZT ADGZP ADHKW ADHZD ADIPN ADMTO ADNBA ADOCK ADQBN ADRTK ADVEK ADYVW ADZXQ AEGPL AEGXH AEHUL AEJOX AEKPW AEKSI AEMDU AEMQT AENEX AENZO AEPUE AETBJ AEWNT AFFQV AFFZL AFIYH AFOFC AFSHK AFXAL AFYAG AGINJ AGKEF AGKRT AGMDO AGQPQ AGQXC AGSYK AGUTN AHGBF AHMBA AHMMS AHXPO AIAGR AIJHB AJBYB AJDVS AJEEA AJNCP AKWXX ALMA_UNASSIGNED_HOLDINGS ALUQC ALXQX APIBT APJGH APWMN AQDSO AQKUS ASPBG ATGXG ATTQO AVNTJ AVWKF AXUDD AZFZN BAWUL BAYMD BCRHZ BEYMZ BHONS BSCLL BTRTY BVRKM BZKNY C45 CAG CDBKE COF CS3 CZ4 DAKXR DIK DILTD DU5 D~K E3Z EBS EE~ EIHJH EJD ENERS F5P F9B FECEO FEDTE FLUFQ FOEOM FOTVD FQBLK GAUVT GJXCC GX1 H13 H5~ HAR HVGLF HW0 HZ~ IOX J21 JXSIZ KAQDR KBUDW KOP KQ8 KSI KSN M-Z MBLQV MHKGH ML0 N9A NGC NOMLY NOYVH NTWIH NU- NVLIB O0~ O9- OAUYM OAWHX OBFPC OCZFY ODMLO OHH OJQWA OJZSN OK1 OPAEJ OVD OWPYF O~Y P2P P6G PAFKI PB- PEELM PQQKQ Q1. Q5Y QBD R44 RD5 RNI ROL ROX ROZ RUSNO RW1 RXO RZF RZO SDH TCURE TEORI TJX TMA TR2 W8F WH7 WOQ X7H X7M YAYTL YKOAZ YXANX ZGI ZKX ZXP ~91 AAYXX CITATION AGORE IQODW 6.Y ABQTQ ABSAR ADJQC ADRIX AFXEN CGR CUY CVF ECM EIF M49 NPM 7QP 7T5 H94 K9. 7X8 |
ID | FETCH-LOGICAL-c380t-54831ca387d17abb4132a05c3e9d729b35641c996bba6af7bfd9ffc0d7e622a3 |
ISSN | 0931-0509 |
IngestDate | Fri Jul 11 14:01:59 EDT 2025 Mon Jun 30 05:53:02 EDT 2025 Wed Feb 19 01:42:18 EST 2025 Mon Jul 21 09:13:42 EDT 2025 Wed Oct 01 03:11:55 EDT 2025 Thu Apr 24 23:07:05 EDT 2025 Sat Sep 20 11:02:52 EDT 2025 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 1 |
Keywords | Endocrinopathy Kidney disease Creatinine diabetic kidney disease Urinary system disease Glomerular filtration Prevalence estimated glomerular filtration rate Hemodialysis Diabetes mellitus serum creatinine Extrarenal dialysis Renal failure sensitivity modification of diet in renal disease (MDRD) study equation |
Language | English |
License | CC BY 4.0 |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c380t-54831ca387d17abb4132a05c3e9d729b35641c996bba6af7bfd9ffc0d7e622a3 |
Notes | local:gfi163 Corresponding and offprint requests to: Rachel J. Middleton, Specialist Registrar in Nephrology, Department of Renal Medicine, Hope Hospital, Stott Lane, Salford M6 8HD, UK. Email: Rachel.middleton@srht.nhs.uk istex:9E0849B6BB4EEAFB3B32A6F7C3AC59474DE3AC14 ark:/67375/HXZ-G3M3CZKK-7 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 |
PMID | 16221715 |
PQID | 218140167 |
PQPubID | 30216 |
PageCount | 5 |
ParticipantIDs | proquest_miscellaneous_67598726 proquest_journals_218140167 pubmed_primary_16221715 pascalfrancis_primary_17447493 crossref_primary_10_1093_ndt_gfi163 crossref_citationtrail_10_1093_ndt_gfi163 istex_primary_ark_67375_HXZ_G3M3CZKK_7 |
ProviderPackageCode | CITATION AAYXX |
PublicationCentury | 2000 |
PublicationDate | 2006-01-01 |
PublicationDateYYYYMMDD | 2006-01-01 |
PublicationDate_xml | – month: 01 year: 2006 text: 2006-01-01 day: 01 |
PublicationDecade | 2000 |
PublicationPlace | Oxford |
PublicationPlace_xml | – name: Oxford – name: England – name: Eynsham |
PublicationTitle | Nephrology, dialysis, transplantation |
PublicationTitleAlternate | Nephrol. Dial. Transplant |
PublicationYear | 2006 |
Publisher | Oxford University Press Oxford Publishing Limited (England) |
Publisher_xml | – name: Oxford University Press – name: Oxford Publishing Limited (England) |
References | key 20171012195120_BIB18 key 20171012195120_BIB19 key 20171012195120_BIB16 key 20171012195120_BIB17 key 20171012195120_BIB10 key 20171012195120_BIB11 key 20171012195120_BIB20 key 20171012195120_BIB14 key 20171012195120_BIB15 key 20171012195120_BIB1 key 20171012195120_BIB12 key 20171012195120_BIB2 key 20171012195120_BIB13 key 20171012195120_BIB3 key 20171012195120_BIB4 key 20171012195120_BIB5 key 20171012195120_BIB6 key 20171012195120_BIB7 key 20171012195120_BIB8 key 20171012195120_BIB9 16611676 - Nephrol Dial Transplant. 2006 Jun;21(6):1732-3; author reply 1733-4 |
References_xml | – ident: key 20171012195120_BIB5 doi: 10.1093/clinchem/38.10.1933 – ident: key 20171012195120_BIB7 doi: 10.2337/diacare.27.2007.S15 – ident: key 20171012195120_BIB15 doi: 10.1681/ASN.2004070539 – ident: key 20171012195120_BIB4 – ident: key 20171012195120_BIB6 doi: 10.1681/ASN.2004060447 – ident: key 20171012195120_BIB2 – ident: key 20171012195120_BIB8 doi: 10.1056/NEJMoa041031 – ident: key 20171012195120_BIB10 doi: 10.2337/diacare.26.6.1806 – ident: key 20171012195120_BIB14 doi: 10.1093/ndt/17.7.1252 – ident: key 20171012195120_BIB9 – ident: key 20171012195120_BIB11 doi: 10.1681/ASN.V7122627 – ident: key 20171012195120_BIB18 doi: 10.2337/diacare.28.4.838 – ident: key 20171012195120_BIB16 doi: 10.1046/j.1523-1755.2003.00712.x – ident: key 20171012195120_BIB12 doi: 10.1016/S0140-6736(98)07368-1 – ident: key 20171012195120_BIB3 doi: 10.1177/14746514020020041401 – ident: key 20171012195120_BIB1 doi: 10.2337/diacare.27.5.1047 – ident: key 20171012195120_BIB17 doi: 10.1046/j.1523-1755.64.s87.5.x – ident: key 20171012195120_BIB19 – ident: key 20171012195120_BIB20 doi: 10.1053/ajkd.2003.50007 – ident: key 20171012195120_BIB13 doi: 10.1016/j.ajkd.2003.07.006 – reference: 16611676 - Nephrol Dial Transplant. 2006 Jun;21(6):1732-3; author reply 1733-4 |
SSID | ssj0009277 |
Score | 2.2390828 |
Snippet | Background. Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes... Diabetes mellitus and chronic kidney disease (CKD) are common and exhibit synergistic associations with premature mortality. Current diabetes guidelines in the... |
SourceID | proquest pubmed pascalfrancis crossref istex |
SourceType | Aggregation Database Index Database Enrichment Source Publisher |
StartPage | 88 |
SubjectTerms | Adult Age Distribution Analysis of Variance Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Associated diseases and complications Biological and medical sciences Blood Glucose - analysis Cohort Studies Comorbidity Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes. Impaired glucose tolerance diabetic kidney disease Diabetic Nephropathies - diagnosis Diabetic Nephropathies - epidemiology Emergency and intensive care: renal failure. Dialysis management Endocrine pancreas. Apud cells (diseases) Endocrinopathies estimated glomerular filtration rate Female Glomerular Filtration Rate Humans Intensive care medicine Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - epidemiology Kidney Function Tests Kidneys Logistic Models Male Medical sciences Middle Aged modification of diet in renal disease (MDRD) study equation Nephrology. Urinary tract diseases Prevalence Probability Prognosis Risk Assessment sensitivity serum creatinine Severity of Illness Index Sex Distribution Tumors of the urinary system United Kingdom - epidemiology |
Title | The unrecognized prevalence of chronic kidney disease in diabetes |
URI | https://api.istex.fr/ark:/67375/HXZ-G3M3CZKK-7/fulltext.pdf https://www.ncbi.nlm.nih.gov/pubmed/16221715 https://www.proquest.com/docview/218140167 https://www.proquest.com/docview/67598726 |
Volume | 21 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 1460-2385 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0009277 issn: 0931-0509 databaseCode: KQ8 dateStart: 19960101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 1460-2385 dateEnd: 20241001 omitProxy: true ssIdentifier: ssj0009277 issn: 0931-0509 databaseCode: DIK dateStart: 19960101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVFQY databaseName: GFMER Free Medical Journals customDbUrl: eissn: 1460-2385 dateEnd: 20241001 omitProxy: true ssIdentifier: ssj0009277 issn: 0931-0509 databaseCode: GX1 dateStart: 19960101 isFulltext: true titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php providerName: Geneva Foundation for Medical Education and Research |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1da9swUGQtjL2MfS_r1hk2CmN4tS1Zih5LaBrWpoORQuiLkGypCw1O1yQw-rP2C3f6iB2zrmx7MUYWZ1t3Ot33IfSe5wkuQKyPC8LLmBjMYs60jktJOTEME1Za08DolA7PyOdJPul0fm5ELa2W6lNxc2teyf9gFcYArzZL9h8wWwOFAbgH_MIVMAzXv8bxqgoxQDfaZfwDfLdZbbi4L3z78XJaVrD1gy_Gxb8Gi-umaHqqAa917orNJ7HFSuz90hVAn8mq7bYfOdtGCL__agtDzxon02AejOE-dLvx-Az1BfyJ75Msqyb9uv9NB77Td0ax0Z32iJDnuGFEC5laVmIOjUnWRo5giMQAIE_8kPZsmNAkBmEi3-TTPpO6RY-e6fq-gL-dBb5OVlXCYTa4MNM0MNJWye3TL2JwdnIixoeTcfupO-K5dSKnlKV7V99j26nMevRD25Z7aDtjlNquGUeTJqyIZ67bZ_1X65K4HO_Dp-z7D2kJQdt2P_-wQblyAfvS-IYqf9Z4nOQzfoQeBpUlOvD09xh1dPUE3R-FoIyn6ADIMNokw6ghw2huokCGkSfDKJBhNK2iNRk-Q-PB4bg_jENnjrjAvWQZg5qL00LiHitTJpUCSSiTSV5gzUvQ1hTOKUkLUKWVklQapkzJjSmSkmmaZRI_R1vVvNIvUWRUT0ne01qBYitNoljJ04JybhihJsFd9GG9UqIIVett85SZ8NETWMCqCr-qXfSunnvla7XcOmvPLXg9RV5f2uhGlovh5Fwc4RHunx8fC9ZFuy2MNDAZIYxwgLSzRpEIXGEhrMhMbG5PF72tnwLLtn442FXz1QJelvMey2gXvfB4bSDD6qQszV_dCXkHPWg23mu0tbxe6TcgGi_VrqPFX8h9vts |
linkProvider | Geneva Foundation for Medical Education and Research |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+unrecognized+prevalence+of+chronic+kidney+disease+in+diabetes&rft.jtitle=Nephrology%2C+dialysis%2C+transplantation&rft.au=Middleton%2C+Rachel+J&rft.au=Foley%2C+Robert+N&rft.au=Hegarty%2C+Janet&rft.au=Cheung%2C+Ching+M&rft.date=2006-01-01&rft.pub=Oxford+Publishing+Limited+%28England%29&rft.issn=0931-0509&rft.eissn=1460-2385&rft.volume=21&rft.issue=1&rft.spage=88&rft_id=info:doi/10.1093%2Fndt%2Fgfi163&rft.externalDBID=NO_FULL_TEXT&rft.externalDocID=958471671 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0931-0509&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0931-0509&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0931-0509&client=summon |