Gene Expression Profiling and Response Signatures Associated With Differential Responses to Infliximab Treatment in Ulcerative Colitis - Toedter, Gary; Li, Katherine; Marano, Colleen; Ma, Keying; Sague, Sarah; Huang, Chris C; Song, Xiao-Yu; Rutgeerts, Paul; Baribaud, Frédéric (The American journal of gastroenterology, 2011)
Keywords: Adult; Antibodies, Monoclonal - administration & dosage; Antibodies, Monoclonal - pharmacology; Biological and medical sciences; Biopsy; Bones, joints and connective tissue. Antiinflammatory agents; Clinical trials; Colitis, Ulcerative - drug therapy; Colitis, Ulcerative - genetics; Down-Regulation - drug effects; Female; Gastroenterology; Gastroenterology. Liver. Pancreas. Abdomen; Gastrointestinal Agents - administration & dosage; Gastrointestinal Agents - pharmacology; Gene expression; Gene Expression Profiling; Genomes; Helper cells; Humans; Immune response (cell-mediated); Immunomodulators; Inflammation; Infliximab; Intestinal Mucosa - metabolism; Lymphocytes T; Male; Medical sciences; Middle Aged; Molecular modelling; Monoclonal antibodies; Mucosa; Other diseases. Semiology; Pharmacology. Drug treatments; Remission; Retrospective Studies; RNA, Messenger - metabolism; Signal transduction; Signal Transduction - genetics; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Th1 Cells - drug effects; Th17 Cells - drug effects; Th2 Cells - drug effects; Tumor necrosis factor- alpha; Ulcerative colitis; Up-Regulation - drug effects; Cytokine; Antipsoriatic agent; Monoclonal antibody; Gene expression; Anti-Tumor Necrosis Factor-alpha; Inflammatory disease; Immunomodulator; Treatment; Infliximab; Anticytokine; Gastroenterology; Digestive diseases; Intestinal disease; Antirheumatic agent; Immunosuppressive agent; Tumor necrosis factor α; Ulcerative colitis