Partial Primary Deficiency of Insulin-Like Growth Factor (IGF)-I Activity Associated with IGF1 Mutation Demonstrates Its Critical Role in Growth and Brain Development - Netchine, Irène; Azzi, Salah; Houang, Muriel; Seurin, Danielle; Perin, Laurence; Ricort, Jean-Marc; Daubas, Claudine; Legay, Christine; Mester, Jan; Herich, Robert; Godeau, François; Le Bouc, Yves (The journal of clinical endocrinology and metabolism, 2009)
Keywords: Arginine; Biological and medical sciences; Brain - growth & development; Brain - metabolism; Cell Proliferation; Child; DNA Mutational Analysis; DNA, Complementary - analysis; Endocrinopathies; Feeding. Feeding behavior; Female; Fetuses; Fundamental and applied biological sciences. Psychology; Gestational age; Glutamine; Growth hormones; Humans; Igf1 gene; Insulin-Like Growth Factor Binding Protein 3 - blood; Insulin-like growth factor I; Insulin-Like Growth Factor I - deficiency; Insulin-Like Growth Factor I - genetics; Insulin-Like Growth Factor I - metabolism; Insulin-like growth factor I receptors; Insulin-like growth factor-binding protein 3; Insulin-like growth factors; Male; Medical sciences; Mutation; Mutation, Missense; Pedigree; Peptides; Phenotypes; Phosphorylation; Postpartum period; Serum levels; Small for gestational age; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vertebrates: endocrinology; Brain; Obesity; Nutrition; Growth; Deficiency; Central nervous system; Nutrition disorder; Metabolic diseases; Insulin like growth factor 1; Biological activity; Encephalon; Insulin like growth factor; Association; Partial; Primary; Genetics; Mutation; Endocrinology; Nutritional status