Renal transplantation and polyomavirus infection: recent clinical facts and controversies

• Published in: Transplant infectious disease Vol. 5; no. 2; pp. 65 - 71
• Main Authors: Kazory, A., Ducloux, D.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Munksgaard International Publishers 01.06.2003; Blackwell
• Subjects: Animals; Biological and medical sciences; BK virus; BK Virus - isolation & purification; Child; Humans; JC virus; JC Virus - isolation & purification; Kidney Transplantation - adverse effects; Medical sciences; nephropathy; Polyomavirus; Polyomavirus - classification; Polyomavirus - isolation & purification; Polyomavirus Infections - virology; Risk Factors; Simian virus 40; simian virus 40 (SV40); Simian virus 40 - isolation & purification; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the urinary system; transplantation; Tumor Virus Infections - virology; Human; Pathogenesis; Polyomavirus; Transplantation; BK virus; Papovaviridae; Homotransplantation; Simian virus 40; Kidney; Virus; Symptomatology; Treatment; JC virus; Surgery; Graft; Bibliographic review
• ISSN: 1398-2273; 1399-3062
• DOI: 10.1034/j.1399-3062.2003.00017.x

: Although many articles have been published on polyomavirus‐induced pathologies in transplant recipients, our knowledge regarding their clinical aspects remains relatively limited. In fact, the number of questions and controversies on the subject seems even to be increasing as new publications continue to appear. This article presents some of these controversies through a brief review of recent clinical facts about the three polyomaviruses that infect humans – JC virus, simian virus 40, and BK virus – as they relate to renal transplantation.