Peroxisome proliferator-activated receptor α activation attenuates the inflammatory response to protect the liver from acute failure by promoting the autophagy pathway - Jiao, M; Ren, F; Zhou, L; Zhang, X; Zhang, L; Wen, T; Wei, L; Wang, X; Shi, H; Bai, L; Zhang, X; Zheng, S; et al. (Cell death & disease, 2014)
Keywords: 631/250/256; 631/80/82/39; 631/80/86; 692/699/1503/1607; Acute Disease; Adenine - analogs & derivatives; Adenine - pharmacology; Adult; Animals; Antibodies; Autophagy - drug effects; Autophagy-Related Protein 7; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cells, Cultured; Chemokines - metabolism; Cytokines - metabolism; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases - metabolism; Female; Galactosamine - toxicity; Hepatitis B - complications; Hepatitis B - diagnosis; Hepatocytes - cytology; Hepatocytes - drug effects; Hepatocytes - metabolism; Humans; Immunology; Inflammation; JNK Mitogen-Activated Protein Kinases - metabolism; Life Sciences; Lipopolysaccharides - toxicity; Liver Failure - chemically induced; Liver Failure - drug therapy; Liver Failure - pathology; Macrophages - cytology; Macrophages - drug effects; Macrophages - metabolism; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins - antagonists & inhibitors; Microtubule-Associated Proteins - genetics; Microtubule-Associated Proteins - metabolism; Middle Aged; Original; original-article; Phosphorylation - drug effects; PPAR alpha - antagonists & inhibitors; PPAR alpha - genetics; PPAR alpha - metabolism; Protective Agents - pharmacology; Protective Agents - therapeutic use; Pyrimidines - pharmacology; Pyrimidines - therapeutic use; RNA Interference; RNA, Small Interfering - metabolism; Toll-Like Receptor 4 - metabolism; Transcription Factor RelA - metabolism