Longitudinal study of a cohort of MSA-C patients in South Italy: survival and clinical features
Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95%...
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| Published in | Neurological sciences Vol. 40; no. 10; pp. 2105 - 2109 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cham
Springer International Publishing
01.10.2019
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1590-1874 1590-3478 1590-3478 |
| DOI | 10.1007/s10072-019-03948-7 |
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| Abstract | Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4–6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7–8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8–10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03–1.11;
p
= 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02–1.06;
p
= 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01–1.06;
p
= 0.021). No predictor of time to death was found. |
|---|---|
| AbstractList | Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4–6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7–8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8–10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03–1.11;
p
= 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02–1.06;
p
= 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01–1.06;
p
= 0.021). No predictor of time to death was found. Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4-6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7-8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8-10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03-1.11; p = 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02-1.06; p = 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01-1.06; p = 0.021). No predictor of time to death was found.Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4-6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7-8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8-10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03-1.11; p = 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02-1.06; p = 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01-1.06; p = 0.021). No predictor of time to death was found. Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4–6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7–8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8–10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03–1.11; p = 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02–1.06; p = 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01–1.06; p = 0.021). No predictor of time to death was found. Sixty-six patients with possible or probable MSA (multiple system atrophy) cerebellar type, personally observed between 2006 and 2018 were retrospectively reviewed. The time point of data collection was January 1, 2019. Forty-nine patients lost independent walking after a median time of 5 years (95% C. I. 4-6). Thirty-two patients were confined to wheelchair after a median time of 7 years (95% C. I. 7-8). Twenty-seven patients were deceased after a median time of 9 years (95% C. I. 8-10). A later onset predicted an earlier loss of independent walking (HR 1.07; 95% C.I. 1.03-1.11; p = 0.001). Higher UMSARS score predicted shorter time to loss of independent walking (HR 1.04; 95% C.I. 1.02-1.06; p = 0.001) and to wheelchair (HR 1.03; 95% C.I. 1.01-1.06; p = 0.021). No predictor of time to death was found. |
| Author | Filla, Alessandro Bruzzese, Dario Saccà, Francesco Bellofatto, Marta Alfieri, Girolamo Antenora, Antonella Bilo, Leonilda De Michele, Giuseppe Roca, Alessandro Barbato, Stefano Lieto, Maria |
| Author_xml | – sequence: 1 givenname: Maria surname: Lieto fullname: Lieto, Maria organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 2 givenname: Alessandro surname: Roca fullname: Roca, Alessandro organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 3 givenname: Dario surname: Bruzzese fullname: Bruzzese, Dario organization: Department of Public Health, Federico II University – sequence: 4 givenname: Antonella surname: Antenora fullname: Antenora, Antonella organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 5 givenname: Girolamo surname: Alfieri fullname: Alfieri, Girolamo organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 6 givenname: Francesco surname: Saccà fullname: Saccà, Francesco organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 7 givenname: Marta surname: Bellofatto fullname: Bellofatto, Marta organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 8 givenname: Leonilda surname: Bilo fullname: Bilo, Leonilda organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 9 givenname: Stefano surname: Barbato fullname: Barbato, Stefano organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 10 givenname: Giuseppe surname: De Michele fullname: De Michele, Giuseppe organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University – sequence: 11 givenname: Alessandro orcidid: 0000-0002-9753-5575 surname: Filla fullname: Filla, Alessandro email: alessandro.filla@unina.it organization: Department of Neuroscience, Reproductive and Odontostomatological Sciences, Federico II University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31152261$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1007_s00455_023_10619_5 crossref_primary_10_1016_j_parkreldis_2021_03_027 crossref_primary_10_1007_s00415_024_12623_7 crossref_primary_10_3233_JPD_212877 crossref_primary_10_1007_s00415_024_12561_4 crossref_primary_10_1007_s00415_024_12784_5 crossref_primary_10_1007_s10072_020_04287_8 crossref_primary_10_1016_j_neurol_2023_11_013 crossref_primary_10_1186_s12883_023_03131_8 crossref_primary_10_1016_j_prdoa_2023_100183 crossref_primary_10_1186_s12883_022_02583_8 crossref_primary_10_2139_ssrn_4071373 crossref_primary_10_1002_mds_28313 crossref_primary_10_1007_s00405_022_07410_x |
| Cites_doi | 10.1212/01.wnl.0000324625.00404.15 10.1093/brain/awn065 10.1016/S1474-4422(15)00058-7 10.1212/WNL.48.2.384 10.1093/brain/awf117 10.1016/S1474-4422(12)70327-7 10.1136/jnnp.57.9.1047 10.1007/s00702-013-1133-7 10.1002/mds.20255 10.1001/archneur.64.2.256 10.1093/brain/awv274 10.1016/S0140-6736(99)04137-9 10.1007/s00702-005-0381-6 10.1016/j.parkreldis.2018.04.016 10.1136/jnnp-2016-314956 10.1002/mds.25927 10.1002/mds.23192 10.1002/mds.23580 10.1017/S0317167100022873 |
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| References | Low, Reich, Jankovic, Shults, Stern, Novak, Tanner, Gilman, Marshall, Wooten, Racette, Chelimsky, Singer, Sletten, Sandroni, Mandrekar (CR7) 2015; 14 Watanabe, Saito, Terao, Ando, Kachi, Mukai, Aiba, Abe, Tamakoshi, Doyu, Hirayama, Sobue (CR4) 2002; 125 Ben-Shlomo, Wenning, Tison, Quinn (CR11) 1997; 48 Kim, Jeon, Lee, Yun (CR12) 2011; 26 Cao, Zhang, Zou, Wei, Ou, Chen, Shang (CR13) 2018; 54 Coon, Sletten, Suarez, Mandrekar, Ahlskog, Bower, Matsumoto, Silber, Benarroch, Fealey, Sandroni, Low, Singer (CR18) 2015; 138 O’Sullivan, Massey, Williams, Silveira-Moriyama, Kempster, Holton, Revesz, Lees (CR9) 2008; 131 Campanella, Filla, De Falco, Mansi, Durivage, Barbeau (CR16) 1980; 7 Tada, Onodera, Tada, Ozawa, Piao, Kakita, Takahashi, Nishizawa (CR10) 2007; 64 Wenning, Geser, Krismer, Seppi, Duerr, Boesch, Köllensperger, Goebel, Pfeiffer, Barone, Pellecchia, Quinn, Koukouni, Fowler, Schrag, Mathias, Giladi, Gurevich, Dupont, Ostergaard, Nilsson, Widner, Oertel, Eggert, Albanese, del Sorbo, Tolosa, Cardozo, Deuschl, Hellriegel, Klockgether, Dodel, Sampaio, Coelho, Djaldetti, Melamed, Gasser, Kamm, Meco, Colosimo, Rascol, Meissner, Tison, Poewe (CR6) 2013; 12 Gilman, Wenning, Low, Brooks, Mathias, Trojanowski, Wood, Colosimo, Dürr, Fowler, Kaufmann, Klockgether, Lees, Poewe, Quinn, Revesz, Robertson, Sandroni, Seppi, Vidailhet (CR15) 2008; 71 Wenning, Tison, Seppi, Sampaio, Diem, Yekhlef, Ghorayeb, Ory, Galitzky, Scaravilli, Bozi, Colosimo, Gilman, Shults, Quinn, Rascol, Poewe (CR17) 2004; 19 CR14 Glasmacher, Leigh, Saha (CR5) 2017; 88 Kollensperger, Geser, Ndayisaba, Boesch, Seppi, Ostergaard, Dupont, Cardozo, Tolosa, Abele, Klockgether, Yekhlef, Tison, Daniels, Deuschl, Coelho, Sampaio, Bozi, Quinn, Schrag, Mathias, Fowler, Nilsson, Widner, Schimke, Oertel, Del Sorbo, Albanese, Pellecchia, Barone, Djaldetti, Colosimo, Meco, Gonzalez-Mandly, Berciano, Gurevich, Giladi, Galitzky, Rascol, Kamm, Gasser, Siebert, Poewe, Wenning (CR3) 2010; 25 Gilman, May, Shults, Tanner, Kukull, Lee, Masliah, Low, Sandroni, Trojanowski, Ozelius, Foroud (CR2) 2005; 112 Figueroa, Singer, Parsaik, Benarroch, Ahlskog, Fealey, Parisi, Sandroni, Mandrekar, Iodice, Low, Bower (CR19) 2014; 29 Roncevic, Palma, Martinez, Goulding, Norcliffe-Kaufmann, Kaufmann (CR20) 2014; 121 Schrag, Ben-Shlomo, Quinn (CR1) 1999; 354 Schulz, Klockgether, Petersen, Jauch, Müller-Schauenburg, Spieker, Voigt, Dichgans (CR8) 1994; 57 A Schrag (3948_CR1) 1999; 354 D Roncevic (3948_CR20) 2014; 121 S Gilman (3948_CR2) 2005; 112 GK Wenning (3948_CR17) 2004; 19 EA Coon (3948_CR18) 2015; 138 M Tada (3948_CR10) 2007; 64 HJ Kim (3948_CR12) 2011; 26 PA Low (3948_CR7) 2015; 14 SA Glasmacher (3948_CR5) 2017; 88 B Cao (3948_CR13) 2018; 54 H Watanabe (3948_CR4) 2002; 125 JJ Figueroa (3948_CR19) 2014; 29 G Campanella (3948_CR16) 1980; 7 3948_CR14 S Gilman (3948_CR15) 2008; 71 SS O’Sullivan (3948_CR9) 2008; 131 GK Wenning (3948_CR6) 2013; 12 JB Schulz (3948_CR8) 1994; 57 M Kollensperger (3948_CR3) 2010; 25 Y Ben-Shlomo (3948_CR11) 1997; 48 |
| References_xml | – volume: 71 start-page: 670 year: 2008 end-page: 676 ident: CR15 article-title: Second consensus statement on the diagnosis of multiple system atrophy publication-title: Neurology doi: 10.1212/01.wnl.0000324625.00404.15 – volume: 131 start-page: 1362 year: 2008 end-page: 1372 ident: CR9 article-title: Clinical outcomes of progressive supranuclear palsy and multiple system atrophy publication-title: Brain doi: 10.1093/brain/awn065 – volume: 14 start-page: 710 year: 2015 end-page: 719 ident: CR7 article-title: Natural history of multiple system atrophy in the USA: a prospective cohort study publication-title: Lancet Neurol doi: 10.1016/S1474-4422(15)00058-7 – volume: 48 start-page: 384 year: 1997 end-page: 393 ident: CR11 article-title: Survival of patients with pathologically proven multiple system atrophy: a meta-analysis publication-title: Neurology doi: 10.1212/WNL.48.2.384 – volume: 125 start-page: 1070 year: 2002 end-page: 1083 ident: CR4 article-title: Progression and prognosis in multiple system atrophy: an analysis of 230 Japanese patients publication-title: Brain doi: 10.1093/brain/awf117 – volume: 12 start-page: 264 year: 2013 end-page: 274 ident: CR6 article-title: The natural history of multiple system atrophy: a prospective European cohort study publication-title: Lancet Neurol doi: 10.1016/S1474-4422(12)70327-7 – volume: 57 start-page: 1047 issue: 9 year: 1994 end-page: 1056 ident: CR8 article-title: Multiple system atrophy: natural history, MRI morphology and dopamine receptor imaging with 123IBZM-SPECT publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.57.9.1047 – volume: 121 start-page: 507 year: 2014 end-page: 512 ident: CR20 article-title: Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival publication-title: J Neural Transm doi: 10.1007/s00702-013-1133-7 – ident: CR14 – volume: 19 start-page: 1391 issue: 12 year: 2004 end-page: 1402 ident: CR17 article-title: Multiple System Atrophy Study Group. Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS) publication-title: Mov Disord doi: 10.1002/mds.20255 – volume: 64 start-page: 256 issue: 2 year: 2007 end-page: 260 ident: CR10 article-title: Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy publication-title: Arch Neurol doi: 10.1001/archneur.64.2.256 – volume: 138 start-page: 3623 year: 2015 end-page: 3631 ident: CR18 article-title: Clinical features and autonomic testing predict survival in multiple system atrophy publication-title: Brain doi: 10.1093/brain/awv274 – volume: 354 start-page: 1771 year: 1999 end-page: 1775 ident: CR1 article-title: Prevalence of progressive supranuclear palsy and multiple system atrophy: a cross- sectional study publication-title: Lancet doi: 10.1016/S0140-6736(99)04137-9 – volume: 112 start-page: 1687 year: 2005 end-page: 1694 ident: CR2 article-title: The North American multiple system atrophy study group publication-title: J Neural Transm doi: 10.1007/s00702-005-0381-6 – volume: 54 start-page: 68 year: 2018 end-page: 73 ident: CR13 article-title: Survival analysis and prognostic nomogram model for multiple system atrophy publication-title: Parkinsonism Relat Disord doi: 10.1016/j.parkreldis.2018.04.016 – volume: 88 start-page: 402 year: 2017 end-page: 4114 ident: CR5 article-title: Predictors of survival in progressive supranuclear palsy and multiple system atrophy: a systematic review and meta-analysis publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp-2016-314956 – volume: 29 start-page: 1151 year: 2014 end-page: 1157 ident: CR19 article-title: Multiple system atrophy: prognostic indicators of survival publication-title: Mov Disord doi: 10.1002/mds.25927 – volume: 25 start-page: 2604 year: 2010 end-page: 2612 ident: CR3 article-title: Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry publication-title: Mov Disord doi: 10.1002/mds.23192 – volume: 26 start-page: 909 year: 2011 end-page: 912 ident: CR12 article-title: Survival of Korean patients with multiple system atrophy publication-title: Mov Disord doi: 10.1002/mds.23580 – volume: 7 start-page: 351 year: 1980 end-page: 357 ident: CR16 article-title: Friedreich’s ataxia in south of Italy: a clinical and biochemical survey of 23 patients publication-title: Can J Neurol Sci doi: 10.1017/S0317167100022873 – volume: 14 start-page: 710 year: 2015 ident: 3948_CR7 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(15)00058-7 – volume: 138 start-page: 3623 year: 2015 ident: 3948_CR18 publication-title: Brain doi: 10.1093/brain/awv274 – volume: 25 start-page: 2604 year: 2010 ident: 3948_CR3 publication-title: Mov Disord doi: 10.1002/mds.23192 – volume: 48 start-page: 384 year: 1997 ident: 3948_CR11 publication-title: Neurology doi: 10.1212/WNL.48.2.384 – volume: 125 start-page: 1070 year: 2002 ident: 3948_CR4 publication-title: Brain doi: 10.1093/brain/awf117 – volume: 29 start-page: 1151 year: 2014 ident: 3948_CR19 publication-title: Mov Disord doi: 10.1002/mds.25927 – volume: 112 start-page: 1687 year: 2005 ident: 3948_CR2 publication-title: J Neural Transm doi: 10.1007/s00702-005-0381-6 – volume: 121 start-page: 507 year: 2014 ident: 3948_CR20 publication-title: J Neural Transm doi: 10.1007/s00702-013-1133-7 – ident: 3948_CR14 – volume: 12 start-page: 264 year: 2013 ident: 3948_CR6 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(12)70327-7 – volume: 54 start-page: 68 year: 2018 ident: 3948_CR13 publication-title: Parkinsonism Relat Disord doi: 10.1016/j.parkreldis.2018.04.016 – volume: 19 start-page: 1391 issue: 12 year: 2004 ident: 3948_CR17 publication-title: Mov Disord doi: 10.1002/mds.20255 – volume: 26 start-page: 909 year: 2011 ident: 3948_CR12 publication-title: Mov Disord doi: 10.1002/mds.23580 – volume: 354 start-page: 1771 year: 1999 ident: 3948_CR1 publication-title: Lancet doi: 10.1016/S0140-6736(99)04137-9 – volume: 131 start-page: 1362 year: 2008 ident: 3948_CR9 publication-title: Brain doi: 10.1093/brain/awn065 – volume: 88 start-page: 402 year: 2017 ident: 3948_CR5 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp-2016-314956 – volume: 7 start-page: 351 year: 1980 ident: 3948_CR16 publication-title: Can J Neurol Sci doi: 10.1017/S0317167100022873 – volume: 57 start-page: 1047 issue: 9 year: 1994 ident: 3948_CR8 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.57.9.1047 – volume: 64 start-page: 256 issue: 2 year: 2007 ident: 3948_CR10 publication-title: Arch Neurol doi: 10.1001/archneur.64.2.256 – volume: 71 start-page: 670 year: 2008 ident: 3948_CR15 publication-title: Neurology doi: 10.1212/01.wnl.0000324625.00404.15 |
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| SubjectTerms | Aged Atrophy Baby supplies Cerebellum Cohort Studies Disease Progression Female Humans Italy Longitudinal Studies Male Medicine Medicine & Public Health Middle Aged Multiple System Atrophy - complications Multiple System Atrophy - mortality Neurology Neuroradiology Neurosciences Neurosurgery Original Article Psychiatry |
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| Title | Longitudinal study of a cohort of MSA-C patients in South Italy: survival and clinical features |
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