Specific Metabolic Characteristics of Women With Former Gestational Diabetes: the Importance of Adipose Tissue

Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome later in life. The higher risk of these metabolic complications is closely associated with adipose tissue. In this review, the importance of ad...

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Published inPhysiological research Vol. 66; no. Suppl 3; pp. S349 - S356
Main Authors VEJRAZKOVA, D., VANKOVA, M., LUKASOVA, P., VCELAK, J., CIRMANOVA, V., HALUZIK, M., BENDLOVA, B.
Format Journal Article
LanguageEnglish
Published Czech Republic Institute of Physiology 26.09.2017
Subjects
Online AccessGet full text
ISSN0862-8408
1802-9973
1802-9973
DOI10.33549/physiolres.933726

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Abstract Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome later in life. The higher risk of these metabolic complications is closely associated with adipose tissue. In this review, the importance of adipose tissue is discussed in relation to GDM, focusing on both the quantity of fat deposits and the metabolic activity of adipose tissue in particular periods of life: neonatal age, childhood, adolescence, and pregnancy followed by nursing. Preventive measures based on body composition and lifestyle habits with special attention to the beneficial effects of breastfeeding are also discussed.
AbstractList Women with a positive history of gestational diabetes mellitus (GDM) face a higher risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome later in life. The higher risk of these metabolic complications is closely associated with adipose tissue. In this review, the importance of adipose tissue is discussed in relation to GDM, focusing on both the quantity of fat deposits and the metabolic activity of adipose tissue in particular periods of life: neonatal age, childhood, adolescence, and pregnancy followed by nursing. Preventive measures based on body composition and lifestyle habits with special attention to the beneficial effects of breastfeeding are also discussed.
Author VEJRAZKOVA, D.
CIRMANOVA, V.
VANKOVA, M.
VCELAK, J.
BENDLOVA, B.
HALUZIK, M.
LUKASOVA, P.
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SubjectTerms Adipose tissue
Adipose Tissue - metabolism
Adolescents
Age
Birth weight
Body composition
Body Composition - physiology
Body fat
Body mass index
Breast feeding
Breast Feeding - trends
Breastfeeding & lactation
Children
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - metabolism
Diabetes, Gestational - epidemiology
Diabetes, Gestational - metabolism
Families & family life
Female
Gestational diabetes
Health risk assessment
Humans
Insulin resistance
Metabolic syndrome
Metabolic Syndrome - epidemiology
Metabolic Syndrome - metabolism
Neonates
Nursing
Obesity
Obesity - epidemiology
Obesity - metabolism
Population
Preeclampsia
Pregnancy
Pregnancy complications
Risk Reduction Behavior
Studies
Tissues
Women
Womens health
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Title Specific Metabolic Characteristics of Women With Former Gestational Diabetes: the Importance of Adipose Tissue
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