LI-RADS treatment response lexicon: review, refresh and resolve with emerging data

• Published in: Abdominal imaging Vol. 46; no. 8; pp. 3549 - 3557
• Main Authors: Ram, Roopa, Kampalath, Rony, Shenoy-Bhangle, Anuradha S., Arora, Sandeep, Kielar, Ania Z., Mendiratta-Lala, Mishal
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2021; Springer Nature B.V
• Subjects: Algorithms; Carcinoma, Hepatocellular - diagnostic imaging; Carcinoma, Hepatocellular - therapy; Cross-Sectional Studies; Evolutionary algorithms; Gastroenterology; Hepatocellular carcinoma; Hepatology; Humans; Imaging; Liver cancer; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - therapy; Magnetic Resonance Imaging; Medicine; Medicine & Public Health; Radiology; Special Section: HCC Treatment; Tomography, X-Ray Computed; Radioembolization; Hepatocellular carcinoma; Treatment response
• ISSN: 2366-004X; 2366-0058; 2366-0058
• DOI: 10.1007/s00261-021-03149-x

The imaging findings after loco regional treatment of hepatocellular carcinoma are variable based on the type of treatment used, the timing interval of imaging after treatment, and the cross-sectional modality used for treatment response assessment. Liver Imaging Reporting and Data System (LI-RADS) Treatment Response Algorithm (TRA) is a relatively new standardized method of evaluating treatment response after loco regional therapy to hepatocellular carcinoma. In this article, we provide an overview of the evolution of the treatment response algorithm, its current applicability and its outlook for the future. We will review current guidelines and discuss proposed changes to the algorithm as a means to continually improve LI-RADS TRA as an assessment tool post-loco regional treatment of hepatocellular carcinoma.