Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells - KIM, SI HYOUNG; CHO, YUN KYUNG; HUH, JI HYE; KANG, JUN GOO; IHM, SUNG-HEE; CHOI, MOON GI; LEE, SEONG JIN (Anticancer research, 2020)
Keywords: Adenine - analogs & derivatives; Adenine - pharmacology; AKT protein; Antibodies; Apoptosis; Apoptosis - drug effects; Bcl-2 protein; Bcl-2-Like Protein 11 - metabolism; Benzamides - pharmacology; BIM protein; Cancer; Cancer therapies; Caspase-3; Cell death; Cell Line, Tumor; Cell survival; Cell Survival - drug effects; Cell viability; Cholecystokinin; Cytotoxicity; Drug dosages; Experiments; Extracellular signal-regulated kinase; Extracellular Signal-Regulated MAP Kinases - metabolism; Flow cytometry; Heat; Heat shock proteins; HSP90 Heat-Shock Proteins - antagonists & inhibitors; HSP90 Heat-Shock Proteins - metabolism; Hsp90 protein; Humans; Indazoles - pharmacology; Inhibitors; Isoxazoles - pharmacology; Kinases; Medical prognosis; Metastasis; Penicillin; Proto-Oncogene Proteins c-akt - metabolism; Pyridines - pharmacology; Resorcinols - pharmacology; Signal Transduction - drug effects; Software; Survival; Thyroid; Thyroid cancer; Thyroid carcinoma; Thyroid Neoplasms - enzymology; Thyroid Neoplasms - pathology; Toxicity; United States--US; South Korea; SNX5422; HSP90 inhibitor; AUY922; Bim; BIIB021; Thyroid carcinoma