Bilateral Masculine Mastoplasia Associated with Imatinib Mesylate： A Case Report and Literature Review
1 CASE REPORT In June 2009, a 29-year-old Chinese male was diagnosed as having Philadelphia chromosome-positive chronic myeloid leukemia （chronic phase）; other than a high white blood cell count in peripheral blood （WBC, 254.00×10^9/L） and splenomegaly, the patient exhibited no abnormal physical sig...
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| Published in | Journal of Huazhong University of Science and Technology. Medical sciences Vol. 31; no. 1; pp. 145 - 146 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Heidelberg
Huazhong University of Science and Technology
01.02.2011
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-0733 1993-1352 |
| DOI | 10.1007/s11596-011-0167-z |
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| Abstract | 1 CASE REPORT
In June 2009, a 29-year-old Chinese male was diagnosed as having Philadelphia chromosome-positive chronic myeloid leukemia （chronic phase）; other than a high white blood cell count in peripheral blood （WBC, 254.00×10^9/L） and splenomegaly, the patient exhibited no abnormal physical signs in mammary glands. He was given hydroxyurea for several days before he received treatment with 400 mg of imatinib mesylate daily. |
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| AbstractList | 1 CASE REPORT
In June 2009, a 29-year-old Chinese male was diagnosed as having Philadelphia chromosome-positive chronic myeloid leukemia （chronic phase）; other than a high white blood cell count in peripheral blood （WBC, 254.00×10^9/L） and splenomegaly, the patient exhibited no abnormal physical signs in mammary glands. He was given hydroxyurea for several days before he received treatment with 400 mg of imatinib mesylate daily. |
| Author | 赵丹 王高翔 李春蕊 孟力 |
| AuthorAffiliation | Department of Hemotology, Tongji Hospital, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan 430030, China |
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| Cites_doi | 10.1016/S0140-6736(03)13554-4 10.3949/ccjm.71.6.511 10.1182/blood-2006-02-005686 10.3346/jkms.2005.20.3.512 10.1210/jc.87.5.2310 10.1177/0009922806294800 10.1056/NEJMoa011573 10.1517/14740330802442382 |
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| Notes | masculine mastoplasia; imatinib mesylate; side effect 1 CASE REPORT In June 2009, a 29-year-old Chinese male was diagnosed as having Philadelphia chromosome-positive chronic myeloid leukemia （chronic phase）; other than a high white blood cell count in peripheral blood （WBC, 254.00×10^9/L） and splenomegaly, the patient exhibited no abnormal physical signs in mammary glands. He was given hydroxyurea for several days before he received treatment with 400 mg of imatinib mesylate daily. 42-1679/R Dan ZHAO , Gaoxiang WANG , Chunrui LI , Li MENG （1 Department of Hemotology, Tongji Hospital, Tongji Medical College, Huangzhong University of Science and Technology, Wuhan 430030, China） ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Review-5 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
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| References | Kim, Chang, Ryu (CR4) 2005; 20 Baccarani, Saglio, Goldman (CR1) 2006; 108 Eckman, Dobs (CR6) 2008; 7 Asciani, Mariani, Arizzi (CR8) 2002; 87 Gambacorti-Passerini, Tornaghi, Cavagnini (CR3) 2003; 361 Goldman (CR9) 2010; 56 Cakan, Kamat (CR5) 2007; 46 Antarjian, Sawyers, Hochhaus (CR2) 2002; 346 Bembo, Carlson (CR7) 2004; 71 C. Gambacorti-Passerini (167_CR3) 2003; 361 N. Cakan (167_CR5) 2007; 46 H. Antarjian (167_CR2) 2002; 346 S. Asciani (167_CR8) 2002; 87 M. Baccarani (167_CR1) 2006; 108 H. Kim (167_CR4) 2005; 20 A. Eckman (167_CR6) 2008; 7 R.D. Goldman (167_CR9) 2010; 56 S.A. Bembo (167_CR7) 2004; 71 18983216 - Expert Opin Drug Saf. 2008 Nov;7(6):691-702 20393092 - Can Fam Physician. 2010 Apr;56(4):344-5 11994382 - J Clin Endocrinol Metab. 2002 May;87(5):2310-9 16709930 - Blood. 2006 Sep 15;108(6):1809-20 15242307 - Cleve Clin J Med. 2004 Jun;71(6):511-7 17579100 - Clin Pediatr (Phila). 2007 Jul;46(6):487-90 15953881 - J Korean Med Sci. 2005 Jun;20(3):512-5 12801741 - Lancet. 2003 Jun 7;361(9373):1954-6 11870241 - N Engl J Med. 2002 Feb 28;346(9):645-52 |
| References_xml | – volume: 361 start-page: 1954 issue: 9373 year: 2003 end-page: 1956 ident: CR3 article-title: Gynaecomastia in men with chronic myeloid leukaemia after imatinib publication-title: Lancet doi: 10.1016/S0140-6736(03)13554-4 – volume: 71 start-page: 511 issue: 6 year: 2004 end-page: 517 ident: CR7 article-title: Gynecomastia: its features, and when and how to treat it publication-title: Cleve Clin J Med doi: 10.3949/ccjm.71.6.511 – volume: 108 start-page: 1809 issue: 6 year: 2006 end-page: 1820 ident: CR1 article-title: Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet publication-title: Blood doi: 10.1182/blood-2006-02-005686 – volume: 56 start-page: 344 issue: 4 year: 2010 end-page: 345 ident: CR9 article-title: Drug-induced gynecomastia in children and adolescents publication-title: Can Fam Physician – volume: 20 start-page: 512 issue: 3 year: 2005 end-page: 515 ident: CR4 article-title: Concurrent male gynecomastia and testicular hydrocele after imatinib mesylate treatment of a gastrointestinal stromal tumor publication-title: J Korean Med Sci doi: 10.3346/jkms.2005.20.3.512 – volume: 87 start-page: 2310 issue: 5 year: 2002 end-page: 2319 ident: CR8 article-title: Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-alpha and -beta during human testicular development and disease publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.87.5.2310 – volume: 46 start-page: 487 issue: 6 year: 2007 end-page: 490 ident: CR5 article-title: Gynecomastia: evaluation and treatment recommendations for primary care providers publication-title: Clin Pediatr (Phila) doi: 10.1177/0009922806294800 – volume: 346 start-page: 645 issue: 9 year: 2002 end-page: 652 ident: CR2 article-title: Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia publication-title: N Engl J Med doi: 10.1056/NEJMoa011573 – volume: 7 start-page: 691 issue: 6 year: 2008 end-page: 702 ident: CR6 article-title: Drug-induced gynecomastia publication-title: Expert Opin Drug Saf doi: 10.1517/14740330802442382 – volume: 46 start-page: 487 issue: 6 year: 2007 ident: 167_CR5 publication-title: Clin Pediatr (Phila) doi: 10.1177/0009922806294800 – volume: 7 start-page: 691 issue: 6 year: 2008 ident: 167_CR6 publication-title: Expert Opin Drug Saf doi: 10.1517/14740330802442382 – volume: 361 start-page: 1954 issue: 9373 year: 2003 ident: 167_CR3 publication-title: Lancet doi: 10.1016/S0140-6736(03)13554-4 – volume: 87 start-page: 2310 issue: 5 year: 2002 ident: 167_CR8 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.87.5.2310 – volume: 108 start-page: 1809 issue: 6 year: 2006 ident: 167_CR1 publication-title: Blood doi: 10.1182/blood-2006-02-005686 – volume: 56 start-page: 344 issue: 4 year: 2010 ident: 167_CR9 publication-title: Can Fam Physician – volume: 71 start-page: 511 issue: 6 year: 2004 ident: 167_CR7 publication-title: Cleve Clin J Med doi: 10.3949/ccjm.71.6.511 – volume: 346 start-page: 645 issue: 9 year: 2002 ident: 167_CR2 publication-title: N Engl J Med doi: 10.1056/NEJMoa011573 – volume: 20 start-page: 512 issue: 3 year: 2005 ident: 167_CR4 publication-title: J Korean Med Sci doi: 10.3346/jkms.2005.20.3.512 – reference: 20393092 - Can Fam Physician. 2010 Apr;56(4):344-5 – reference: 11870241 - N Engl J Med. 2002 Feb 28;346(9):645-52 – reference: 17579100 - Clin Pediatr (Phila). 2007 Jul;46(6):487-90 – reference: 18983216 - Expert Opin Drug Saf. 2008 Nov;7(6):691-702 – reference: 16709930 - Blood. 2006 Sep 15;108(6):1809-20 – reference: 15242307 - Cleve Clin J Med. 2004 Jun;71(6):511-7 – reference: 11994382 - J Clin Endocrinol Metab. 2002 May;87(5):2310-9 – reference: 12801741 - Lancet. 2003 Jun 7;361(9373):1954-6 – reference: 15953881 - J Korean Med Sci. 2005 Jun;20(3):512-5 |
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In June 2009, a 29-year-old Chinese male was diagnosed as having Philadelphia chromosome-positive chronic myeloid leukemia （chronic phase）;... |
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| SubjectTerms | Adult Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Benzamides Gynecomastia - chemically induced Humans Imatinib Mesylate Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Male Medicine Medicine & Public Health Piperazines - adverse effects Piperazines - therapeutic use Pyrimidines - adverse effects Pyrimidines - therapeutic use 乳腺增生 双边 外周血白细胞 文献 甲磺酸 病例报告 白血病 细胞计数 |
| Title | Bilateral Masculine Mastoplasia Associated with Imatinib Mesylate： A Case Report and Literature Review |
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