Knockout of hexokinase 2 regulates mitochondrial dysfunction and activates the NLRP3 signal pathway in the rumen epithelial cells of dairy cows - Yang, Tianyu; Lu, Zhiqi; Song, Han; Chen, Yuhang; Jiang, Maocheng; Zhan, Kang; Zhao, Guoqi (International journal of biological macromolecules, 2025)
Keywords: Animals; Cattle; Epithelial Cells - metabolism; Female; Gene Knockout Techniques; Hexokinase - deficiency; Hexokinase - genetics; Hexokinase - metabolism; Hexokinase 2; High-concentrate diet; Mitochondria - genetics; Mitochondria - metabolism; Mitochondria - pathology; Mitochondrial function; NLR Family, Pyrin Domain-Containing 3 Protein - metabolism; NLRP3 signaling pathway; Oxidative Stress; Reactive Oxygen Species - metabolism; Rumen - cytology; Rumen - metabolism; Ruminal epithelium; Signal Transduction; NLRP3 signaling pathway; Hexokinase 2; Mitochondrial function; Ruminal epithelium; High-concentrate diet