Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging
We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of 30 mm 2 ( i.e. , 6.4 mm 4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing 122 grams with dimensions of 4 cm 4 cm 1...
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| Published in | Lab on a chip Vol. 12; no. 7; pp. 1242 - 1245 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
07.04.2012
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1473-0197 1473-0189 1473-0189 |
| DOI | 10.1039/c2lc21072j |
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| Abstract | We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of 30 mm
2
(
i.e.
, 6.4 mm 4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing 122 grams with dimensions of 4 cm 4 cm 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image,
i.e.
, >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of
e.g.
, 10 to 80 m. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 25 planes), phase and amplitude images of dense samples can be recovered
without
the need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for
e.g.
, pathology needs in resource limited settings.
We present a field-portable and cost-effective lensfree pixel super-resolution microscope that offers sub-micron resolution over a field-of-view of 30 mm
2
for imaging of dense and connected specimens on a chip. |
|---|---|
| AbstractList | We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of similar to 30 mm super(2) (i.e., similar to 6.4 mm similar to 4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing similar to 122 grams with dimensions of 4 cm 4 cm 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image, i.e., >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of e.g., similar to 10 to 80 mu m. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 2-5 planes), phase and amplitude images of dense samples can be recovered withoutthe need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g., pathology needs in resource limited settings. We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of 30 mm 2 ( i.e. , 6.4 mm 4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing 122 grams with dimensions of 4 cm 4 cm 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image, i.e. , >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of e.g. , 10 to 80 m. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 25 planes), phase and amplitude images of dense samples can be recovered without the need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g. , pathology needs in resource limited settings. We present a field-portable and cost-effective lensfree pixel super-resolution microscope that offers sub-micron resolution over a field-of-view of 30 mm 2 for imaging of dense and connected specimens on a chip. We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of ~30 mm(2) (i.e., ~6.4 mm × ~4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing ~122 grams with dimensions of 4 cm × 4 cm × 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image, i.e., >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of e.g., ~10 to 80 μm. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 2-5 planes), phase and amplitude images of dense samples can be recovered without the need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g., pathology needs in resource limited settings. We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of ~30 mm(2) (i.e., ~6.4 mm × ~4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing ~122 grams with dimensions of 4 cm × 4 cm × 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image, i.e., >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of e.g., ~10 to 80 μm. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 2-5 planes), phase and amplitude images of dense samples can be recovered without the need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g., pathology needs in resource limited settings.We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of ~30 mm(2) (i.e., ~6.4 mm × ~4.6 mm) using pixel super-resolution and iterative phase recovery techniques. Weighing ~122 grams with dimensions of 4 cm × 4 cm × 15 cm, this microscope records lensfree in-line holograms of specimens onto an opto-electronic sensor-array using partially coherent illumination. To reconstruct the phase and amplitude images of dense samples (with >0.3 billion pixels in each image, i.e., >0.6 billion pixels total), we employ a multi-height imaging approach, where by using a mechanical interface the sensor-to-sample distance is dynamically changed by random discrete steps of e.g., ~10 to 80 μm. By digitally propagating back and forth between these multi-height super-resolved holograms (corresponding to typically 2-5 planes), phase and amplitude images of dense samples can be recovered without the need for any spatial masks or filtering. We demonstrate the performance of this field-portable multi-height lensfree microscope by imaging Papanicolaou smears (also known as Pap tests). Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g., pathology needs in resource limited settings. |
| Author | Ozcan, Aydogan Sikora, Uzair Greenbaum, Alon |
| AuthorAffiliation | UCLA Bioengineering Department California NanoSystems Institute (CNSI) University of California UCLA Electrical Engineering Department |
| AuthorAffiliation_xml | – name: California NanoSystems Institute (CNSI) – name: University of California – name: UCLA Bioengineering Department – name: UCLA Electrical Engineering Department |
| Author_xml | – sequence: 1 givenname: Alon surname: Greenbaum fullname: Greenbaum, Alon – sequence: 2 givenname: Uzair surname: Sikora fullname: Sikora, Uzair – sequence: 3 givenname: Aydogan surname: Ozcan fullname: Ozcan, Aydogan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22334329$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1371/journal.pone.0006320 10.1039/c004829a 10.1364/OL.3.000027 10.1364/JOSAA.10.000423 10.1371/journal.pone.0011890 10.1002/dc.10158 10.1371/journal.pmed.0020182 10.1364/AO.41.004489 10.1364/OL.31.001211 10.1039/B604676B 10.1073/pnas.1015638108 10.1159/000326278 10.1039/C0LC00358A 10.1186/1758-3284-2-10 10.14219/jada.archive.2006.0180 10.1117/1.601623 10.1002/cncr.20599 10.1364/OE.17.013040 10.1364/OE.18.011181 10.1039/c0lc00431f 10.1364/JOSAA.3.001897 10.1364/OPEX.13.008693 10.1021/ac801729t 10.1002/cyto.a.20205 10.1039/C0LC00340A 10.1073/pnas.191361398 10.1364/OE.20.003129 10.1016/j.virol.2010.06.025 10.1016/j.addr.2009.11.015 10.1016/S0030-4018(01)01556-5 10.2174/1874285801004010030 10.1111/j.1365-2303.2006.00340.x 10.1364/OE.18.004717 10.1364/OL.29.001132 10.1364/OE.19.008179 10.1039/c000453g 10.1039/c0lc00684j |
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| References | Fienup (c2lc21072j-(cit27)/*[position()=1]) 1978; 3 Sass (c2lc21072j-(cit35)/*[position()=1]) 2004; 48 Baker (c2lc21072j-(cit36)/*[position()=1]) 2002; 27 Pedrini (c2lc21072j-(cit15)/*[position()=1]) 2002; 41 Greenbaum (c2lc21072j-(cit31)/*[position()=1]) 2012; 20 Heng (c2lc21072j-(cit20)/*[position()=1]) 2006; 6 Brady (c2lc21072j-(cit19)/*[position()=1]) 2009; 17 Isikman (c2lc21072j-(cit21)/*[position()=1]) 2011; 108 Oh (c2lc21072j-(cit23)/*[position()=1]) 2010; 18 Fremont-Smith (c2lc21072j-(cit34)/*[position()=1]) 2004; 102 Rodriguez (c2lc21072j-(cit1)/*[position()=1]) 2005; 2 Desai (c2lc21072j-(cit10)/*[position()=1]) 2011; 11 Mudanyali (c2lc21072j-(cit24)/*[position()=1]) 2010; 10 Rahman (c2lc21072j-(cit2)/*[position()=1]) 2010; 2 Vannahme (c2lc21072j-(cit7)/*[position()=1]) 2011; 19 Balsam (c2lc21072j-(cit3)/*[position()=1]) 2011; 11 Mann (c2lc21072j-(cit17)/*[position()=1]) 2005; 13 Garcia-Sucerquia (c2lc21072j-(cit18)/*[position()=1]) 2006; 31 Duggan (c2lc21072j-(cit37)/*[position()=1]) 2006; 17 Hauck (c2lc21072j-(cit5)/*[position()=1]) 2010; 62 Hardie (c2lc21072j-(cit33)/*[position()=1]) 1998; 37 Fienup (c2lc21072j-(cit29)/*[position()=1]) 1986; 3 Breslauer (c2lc21072j-(cit4)/*[position()=1]) 2003; 4 Li (c2lc21072j-(cit6)/*[position()=1]) 2008; 80 Goddard (c2lc21072j-(cit11)/*[position()=1]) 2006; 69 Repetto (c2lc21072j-(cit16)/*[position()=1]) 2004; 29 Kuhn (c2lc21072j-(cit12)/*[position()=1]) 2010; 4 Bishara (c2lc21072j-(cit25)/*[position()=1]) 2010; 18 Hu (c2lc21072j-(cit38)/*[position()=1]) 2010; 405 Xu (c2lc21072j-(cit14)/*[position()=1]) 2001; 98 Bishara (c2lc21072j-(cit26)/*[position()=1]) 2011; 11 Zhu (c2lc21072j-(cit13)/*[position()=1]) 2011; 11 Miller (c2lc21072j-(cit8)/*[position()=1]) 2010; 5 Mudanyali (c2lc21072j-(cit22)/*[position()=1]) 2010; 10 Koren (c2lc21072j-(cit28)/*[position()=1]) 1993; 10 Allen (c2lc21072j-(cit30)/*[position()=1]) 2001; 199 Wong (c2lc21072j-(cit9)/*[position()=1]) 2010; 137 |
| References_xml | – issn: 2003 issue: vol. 20 end-page: p 2136 publication-title: IEEE Signal Processing Magazine doi: Park Park Kang – volume: 4 start-page: e6320 year: 2003 ident: c2lc21072j-(cit4)/*[position()=1] publication-title: PLoS One doi: 10.1371/journal.pone.0006320 – volume: 10 start-page: 2419 year: 2010 ident: c2lc21072j-(cit24)/*[position()=1] publication-title: Lab Chip doi: 10.1039/c004829a – volume: 3 start-page: 27 year: 1978 ident: c2lc21072j-(cit27)/*[position()=1] publication-title: Opt. Lett. doi: 10.1364/OL.3.000027 – volume: 10 start-page: 423 year: 1993 ident: c2lc21072j-(cit28)/*[position()=1] publication-title: J. Opt. Soc. Am. A doi: 10.1364/JOSAA.10.000423 – volume: 5 start-page: e11890 year: 2010 ident: c2lc21072j-(cit8)/*[position()=1] publication-title: PLoS One doi: 10.1371/journal.pone.0011890 – volume: 27 start-page: 185 year: 2002 ident: c2lc21072j-(cit36)/*[position()=1] publication-title: Diagn. Cytopathol. doi: 10.1002/dc.10158 – volume: 2 start-page: e182 year: 2005 ident: c2lc21072j-(cit1)/*[position()=1] publication-title: PLoS Med. doi: 10.1371/journal.pmed.0020182 – volume: 41 start-page: 4489 year: 2002 ident: c2lc21072j-(cit15)/*[position()=1] publication-title: Appl. Opt. doi: 10.1364/AO.41.004489 – volume: 31 start-page: 1211 year: 2006 ident: c2lc21072j-(cit18)/*[position()=1] publication-title: Opt. Lett. doi: 10.1364/OL.31.001211 – volume: 6 start-page: 1274 year: 2006 ident: c2lc21072j-(cit20)/*[position()=1] publication-title: Lab Chip doi: 10.1039/B604676B – volume: 108 start-page: 7296 year: 2011 ident: c2lc21072j-(cit21)/*[position()=1] publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.1015638108 – volume: 48 start-page: 17 year: 2004 ident: c2lc21072j-(cit35)/*[position()=1] publication-title: Acta Cytol. doi: 10.1159/000326278 – volume: 11 start-page: 315 year: 2011 ident: c2lc21072j-(cit13)/*[position()=1] publication-title: Lab Chip doi: 10.1039/C0LC00358A – volume: 2 start-page: 10 year: 2010 ident: c2lc21072j-(cit2)/*[position()=1] publication-title: Head Neck Oncol. doi: 10.1186/1758-3284-2-10 – volume: 137 start-page: 313 year: 2010 ident: c2lc21072j-(cit9)/*[position()=1] publication-title: J. Am. Dent. Assoc., JADA doi: 10.14219/jada.archive.2006.0180 – volume: 37 start-page: 247 year: 1998 ident: c2lc21072j-(cit33)/*[position()=1] publication-title: Opt. Eng. doi: 10.1117/1.601623 – volume: 102 start-page: 269 year: 2004 ident: c2lc21072j-(cit34)/*[position()=1] publication-title: Cancer Cytopathol. doi: 10.1002/cncr.20599 – volume: 17 start-page: 13040 year: 2009 ident: c2lc21072j-(cit19)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OE.17.013040 – volume: 18 start-page: 11181 year: 2010 ident: c2lc21072j-(cit25)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OE.18.011181 – volume: 11 start-page: 941 year: 2011 ident: c2lc21072j-(cit3)/*[position()=1] publication-title: Lab Chip doi: 10.1039/c0lc00431f – volume: 3 start-page: 1897 year: 1986 ident: c2lc21072j-(cit29)/*[position()=1] publication-title: J. Opt. Soc. Am. A doi: 10.1364/JOSAA.3.001897 – volume: 13 start-page: 8693 year: 2005 ident: c2lc21072j-(cit17)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OPEX.13.008693 – volume: 80 start-page: 9131 year: 2008 ident: c2lc21072j-(cit6)/*[position()=1] publication-title: Anal. Chem. doi: 10.1021/ac801729t – volume: 69 start-page: 66 year: 2006 ident: c2lc21072j-(cit11)/*[position()=1] publication-title: Cytometry, Part A doi: 10.1002/cyto.a.20205 – volume: 11 start-page: 194 year: 2011 ident: c2lc21072j-(cit10)/*[position()=1] publication-title: Lab Chip doi: 10.1039/C0LC00340A – volume: 98 start-page: 11301 year: 2001 ident: c2lc21072j-(cit14)/*[position()=1] publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.191361398 – volume: 20 start-page: 3129 year: 2012 ident: c2lc21072j-(cit31)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OE.20.003129 – volume: 405 start-page: 342 year: 2010 ident: c2lc21072j-(cit38)/*[position()=1] publication-title: Virology doi: 10.1016/j.virol.2010.06.025 – volume: 62 start-page: 438 year: 2010 ident: c2lc21072j-(cit5)/*[position()=1] publication-title: Adv. Drug Delivery Rev. doi: 10.1016/j.addr.2009.11.015 – volume: 199 start-page: 65 year: 2001 ident: c2lc21072j-(cit30)/*[position()=1] publication-title: Opt. Commun. doi: 10.1016/S0030-4018(01)01556-5 – volume: 4 start-page: 30 year: 2010 ident: c2lc21072j-(cit12)/*[position()=1] publication-title: Open Microbiol. J. doi: 10.2174/1874285801004010030 – volume: 17 start-page: 73 year: 2006 ident: c2lc21072j-(cit37)/*[position()=1] publication-title: Cytopathology doi: 10.1111/j.1365-2303.2006.00340.x – volume: 18 start-page: 4717 year: 2010 ident: c2lc21072j-(cit23)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OE.18.004717 – volume: 29 start-page: 1132 year: 2004 ident: c2lc21072j-(cit16)/*[position()=1] publication-title: Opt. Lett. doi: 10.1364/OL.29.001132 – volume: 19 start-page: 8179 year: 2011 ident: c2lc21072j-(cit7)/*[position()=1] publication-title: Opt. Express doi: 10.1364/OE.19.008179 – volume: 10 start-page: 1417 year: 2010 ident: c2lc21072j-(cit22)/*[position()=1] publication-title: Lab Chip doi: 10.1039/c000453g – volume: 11 start-page: 1276 year: 2011 ident: c2lc21072j-(cit26)/*[position()=1] publication-title: Lab Chip doi: 10.1039/c0lc00684j |
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| Snippet | We report a field-portable lensfree microscope that can image dense and connected specimens with sub-micron resolution over a large field-of-view of 30 mm
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| SubjectTerms | Algorithms Amplitudes Female Holograms Holography Humans Imaging Lenses Microscopes Microscopy Papanicolaou Test Pixels Uterine Cervical Neoplasms - diagnosis Vaginal Smears |
| Title | Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging |
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