Ocular Syphilis: An Update
This review aims to provide an update on the clinical presentation, diagnosis, and treatment of ocular syphilis. While ocular syphilis is not a new phenomenon, recent resurgence in the incidence of overall syphilis, particularly among HIV-positive individuals, has sparked a new interest in an old di...
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| Published in | Ocular immunology and inflammation Vol. 27; no. 1; pp. 117 - 125 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Taylor & Francis
02.01.2019
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0927-3948 1744-5078 1744-5078 |
| DOI | 10.1080/09273948.2017.1371765 |
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| Abstract | This review aims to provide an update on the clinical presentation, diagnosis, and treatment of ocular syphilis. While ocular syphilis is not a new phenomenon, recent resurgence in the incidence of overall syphilis, particularly among HIV-positive individuals, has sparked a new interest in an old disease. The challenge of ocular syphilis is manifold: firstly, it manifests in a spectrum of ways that can occur at any stage of the disease, with the most common finding being panuveitis. It may occur as early as 6 weeks after transmission and may be the only presenting feature of systemic syphilis; secondly, the relationship between HIV and syphilis has been established, as primary syphilis facilitates HIV transmission and HIV may modify the natural course of syphilis, increasing the propensity of the disease to progress to neurosyphilis. The authors present the latest updates to the changing landscape of ocular syphilis. |
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| AbstractList | This review aims to provide an update on the clinical presentation, diagnosis, and treatment of ocular syphilis. While ocular syphilis is not a new phenomenon, recent resurgence in the incidence of overall syphilis, particularly among HIV-positive individuals, has sparked a new interest in an old disease. The challenge of ocular syphilis is manifold: firstly, it manifests in a spectrum of ways that can occur at any stage of the disease, with the most common finding being panuveitis. It may occur as early as 6 weeks after transmission and may be the only presenting feature of systemic syphilis; secondly, the relationship between HIV and syphilis has been established, as primary syphilis facilitates HIV transmission and HIV may modify the natural course of syphilis, increasing the propensity of the disease to progress to neurosyphilis. The authors present the latest updates to the changing landscape of ocular syphilis. This review aims to provide an update on the clinical presentation, diagnosis, and treatment of ocular syphilis. While ocular syphilis is not a new phenomenon, recent resurgence in the incidence of overall syphilis, particularly among HIV-positive individuals, has sparked a new interest in an old disease. The challenge of ocular syphilis is manifold: firstly, it manifests in a spectrum of ways that can occur at any stage of the disease, with the most common finding being panuveitis. It may occur as early as 6 weeks after transmission and may be the only presenting feature of systemic syphilis; secondly, the relationship between HIV and syphilis has been established, as primary syphilis facilitates HIV transmission and HIV may modify the natural course of syphilis, increasing the propensity of the disease to progress to neurosyphilis. The authors present the latest updates to the changing landscape of ocular syphilis.This review aims to provide an update on the clinical presentation, diagnosis, and treatment of ocular syphilis. While ocular syphilis is not a new phenomenon, recent resurgence in the incidence of overall syphilis, particularly among HIV-positive individuals, has sparked a new interest in an old disease. The challenge of ocular syphilis is manifold: firstly, it manifests in a spectrum of ways that can occur at any stage of the disease, with the most common finding being panuveitis. It may occur as early as 6 weeks after transmission and may be the only presenting feature of systemic syphilis; secondly, the relationship between HIV and syphilis has been established, as primary syphilis facilitates HIV transmission and HIV may modify the natural course of syphilis, increasing the propensity of the disease to progress to neurosyphilis. The authors present the latest updates to the changing landscape of ocular syphilis. |
| Author | Pavesio, Carlos Ching Wen Ho, Dawn See Yin, Leo Agrawal, Rupesh Shah, Janika Biswas, Jyotirmay Gupta, Vishali Chen, Elizabeth J. Dutta Majumder, Parthopratim |
| Author_xml | – sequence: 1 givenname: Parthopratim surname: Dutta Majumder fullname: Dutta Majumder, Parthopratim organization: Sankara Nethralaya, Medical Research Foundation – sequence: 2 givenname: Elizabeth J. surname: Chen fullname: Chen, Elizabeth J. organization: Yong Loo Lin School of Medicine, National University of Singapore – sequence: 3 givenname: Janika surname: Shah fullname: Shah, Janika organization: Singapore National Eye Centre – sequence: 4 givenname: Dawn surname: Ching Wen Ho fullname: Ching Wen Ho, Dawn organization: Yong Loo Lin School of Medicine, National University of Singapore – sequence: 5 givenname: Jyotirmay surname: Biswas fullname: Biswas, Jyotirmay organization: Sankara Nethralaya, Medical Research Foundation – sequence: 6 givenname: Leo surname: See Yin fullname: See Yin, Leo organization: Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital – sequence: 7 givenname: Vishali surname: Gupta fullname: Gupta, Vishali organization: Postgraduate Institute of Medical Education and Research – sequence: 8 givenname: Carlos surname: Pavesio fullname: Pavesio, Carlos organization: Moorfields Eye Hospital, NHS Foundation Trust – sequence: 9 givenname: Rupesh surname: Agrawal fullname: Agrawal, Rupesh email: rupeshttsh@gmail.com organization: National Healthcare Group Eye Institute, Tan Tock Seng Hospital |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29020491$$D View this record in MEDLINE/PubMed |
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| Title | Ocular Syphilis: An Update |
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